The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A New Theranostic System Based on Gold Nanocages and Phase-Change Materials with Unique Features for Photoacoustic Imaging and Controlled Release
Open accessAbstract
This communication reports a new theranostic system with a combination of capabilities to both enhance the contrast of photoacoustic (PA) imaging and control the release of a chemical or biological effector by high-intensity focused ultrasound (HIFU). The fabrication of this system simply involves filling the hollow interiors of gold nanocages with a phase-change material (PCM) such as 1-tetradecanol that has a melting point of 38-39 °C. The PCM can be premixed and thus loaded with a dye, as well as other chemical or biological effectors. When exposed to direct heating or HIFU, the PCM will melt and escape from the interiors of nanocages through small pores on the surface, concurrently releasing the encapsulated molecules into the surrounding medium. We can control the release profile by varying the power of HIFU, the duration of exposure to HIFU, or both.
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Citations
Cites
Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems
Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J. S., Chin, S.-F., Sherry, A. D., Boothman, D. A., & Gao, J. (2006) · Nano Letters · doi:10.1021/nl061412u · Cited by 1,238
Cited by
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164
Synthesis, Properties, and Applications of Hollow Micro-/Nanostructures
Wang, X., Feng, J., Bai, Y., Zhang, Q., & Yin, Y. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00731 · Cited by 1,456
Gold Nanomaterials at Work in Biomedicine
Yang, X., Yang, M., Pang, B., Vara, M., & Xia, Y. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00193 · Cited by 1,162
Self-citationLee, H., Song, C., Hong, Y. S., Kim, M., Cho, H. R., Kang, T., Shin, K., Choi, S. H., Hyeon, T., & Kim, D.-H. (2017) · Science Advances · doi:10.1126/sciadv.1601314 · Cited by 1,118
Self-citationXia, X., Wang, Y., Ruditskiy, A., & Xia, Y. (2013) · Advanced Materials · doi:10.1002/adma.201302820 · Cited by 1,019
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Metadata
- Authors
- Moon, G. D., Choi, S.-W., Cai, X., Li, W., Cho, E. C., Jeong, U., Wang, L. V., & Xia, Y.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-03-14
- Volume
- 133
- Issue
- 13
- Pages
- 4762-4765
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2042079908
- Cited by
- 405
- References
- 1
- FWCI
- 19.33
- Type
- journal article
- Language
- en
- Open access
- green
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- Moon, G. D., Choi, S.-W., Cai, X., Li, W., Cho, E. C., Jeong, U., Wang, L. V., & Xia, Y. (2011). A New Theranostic System Based on Gold Nanocages and Phase-Change Materials with Unique Features for Photoacoustic Imaging and Controlled Release. Journal of the American Chemical Society. https://doi.org/10.1021/ja200894u
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