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Cited by 405

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

A New Theranostic System Based on Gold Nanocages and Phase-Change Materials with Unique Features for Photoacoustic Imaging and Controlled Release

Open access
Moon, Geon Dae, Choi, Sung-Wook, Cai, Xin, Li, Weiyang, Cho, Eun Chul, Jeong, Unyong, Wang, Lihong V., Xia, Younan·2011·Journal of the American Chemical Society

Abstract

This communication reports a new theranostic system with a combination of capabilities to both enhance the contrast of photoacoustic (PA) imaging and control the release of a chemical or biological effector by high-intensity focused ultrasound (HIFU). The fabrication of this system simply involves filling the hollow interiors of gold nanocages with a phase-change material (PCM) such as 1-tetradecanol that has a melting point of 38-39 °C. The PCM can be premixed and thus loaded with a dye, as well as other chemical or biological effectors. When exposed to direct heating or HIFU, the PCM will melt and escape from the interiors of nanocages through small pores on the surface, concurrently releasing the encapsulated molecules into the surrounding medium. We can control the release profile by varying the power of HIFU, the duration of exposure to HIFU, or both.

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Metadata

Authors
Moon, G. D., Choi, S.-W., Cai, X., Li, W., Cho, E. C., Jeong, U., Wang, L. V., & Xia, Y.
Venue
Journal of the American Chemical Society
Published
2011-03-14
Volume
133
Issue
13
Pages
4762-4765
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2042079908
Cited by
405
References
1
FWCI
19.33
Type
journal article
Language
en
Open access
green

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Moon, G. D., Choi, S.-W., Cai, X., Li, W., Cho, E. C., Jeong, U., Wang, L. V., & Xia, Y. (2011). A New Theranostic System Based on Gold Nanocages and Phase-Change Materials with Unique Features for Photoacoustic Imaging and Controlled Release. Journal of the American Chemical Society. https://doi.org/10.1021/ja200894u

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