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Anti-Markovnikov Hydroamination of Alkenes Catalyzed by an Organic Photoredox System

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Nguyen, Tien M., Nicewicz, David A.·2013·Journal of the American Chemical Society

Abstract

Herein we report a metal-free method for the direct anti-Markovnikov hydroamination of unsaturated amines. Irradiation of the amine substrates with visible light in the presence of catalytic quantities of easily synthesized 9-mesityl-10-methylacridinium tetrafluoroborate and thiophenol as a hydrogen-atom donor furnished the nitrogen-containing heterocycles with complete regiocontrol. Two examples of intermolecular anti-Markovnikov alkene hydroamination are also disclosed.

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Metadata

Authors
Nguyen, T. M., & Nicewicz, D. A.
Venue
Journal of the American Chemical Society
Published
2013-06-19
Volume
135
Issue
26
Pages
9588-9591
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2074545790
Cited by
331
References
0
FWCI
14.01
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Anti-Markovnikov Hydroamination of Alkenes Catalyzed by an Organic Photoredox System. https://app.cochat.ai/papers/10.1021/ja4031616
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Nguyen, T. M., & Nicewicz, D. A. (2013). Anti-Markovnikov Hydroamination of Alkenes Catalyzed by an Organic Photoredox System. Journal of the American Chemical Society. https://doi.org/10.1021/ja4031616

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.