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Cited by 431

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Photoredox α-Vinylation of α-Amino Acids and N-Aryl Amines

Open access
Noble, Adam, MacMillan, David W. C.·2014·Journal of the American Chemical Society

Abstract

A new coupling protocol has been developed that allows the union of vinyl sulfones with photoredox-generated α-amino radicals to provide allylic amines of broad diversity. Direct C-H vinylations of N-aryl tertiary amines, as well as decarboxylative vinylations of N-Boc α-amino acids, proceed in high yield and with excellent olefin geometry control. The utility of this new allyl amine forming reaction has been demonstrated via the syntheses of several natural products and a number of established pharmacophores.

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Crossref · 10.1021/ja506094d

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Metadata

Authors
Noble, A., & MacMillan, D. W. C.
Venue
Journal of the American Chemical Society
Published
2014-08-11
Volume
136
Issue
33
Pages
11602-11605
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2313377134
Cited by
431
References
1
FWCI
21.10
Type
journal article
Language
en
Open access
hybrid

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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