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Cited by 170

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Oxidative Nanopeeling Chemistry-Based Synthesis and Photodynamic and Photothermal Therapeutic Applications of Plasmonic Core-Petal Nanostructures

Kumar, Amit, Kumar, Sumit, Rhim, Won-Kyu, Kim, Gyeong-Hwan, Nam, Jwa-Min·2014·Journal of the American Chemical Society

Abstract

The precise control of plasmonic nanostructures and their use for less invasive apoptotic pathway-based therapeutics are important but challenging. Here, we introduce a highly controlled synthetic strategy for plasmonic core-petal nanoparticles (CPNs) with massively branched and plasmonically coupled nanostructures. The formation of CPNs was facilitated by the gold chloride-induced oxidative disassembly and rupture of the polydopamine corona around Au nanoparticles and subsequent growth of Au nanopetals. We show that CPNs can act as multifunctional nanoprobes that induce dual photodynamic and photothermal therapeutic effects without a need for organic photosensitizers, coupled with the generation of reactive oxygen species (ROS), and allow for imaging and analyzing cells. Near-infrared laser-activated CPNs can optically monitor and efficiently kill cancer cells via apoptotic pathway by dual phototherapeutic effects and ROS-mediated oxidative intracellular damage with a relatively mild increase in temperature, low laser power, and short laser exposure time.

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Metadata

Authors
Kumar, A., Kumar, S., Rhim, W.-K., Kim, G.-H., & Nam, J.-M.
Venue
Journal of the American Chemical Society
Published
2014-11-11
Volume
136
Issue
46
Pages
16317-16325
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2318415498
Cited by
170
References
8
FWCI
8.11
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Oxidative Nanopeeling Chemistry-Based Synthesis and Photodynamic and Photothermal Therapeutic Applications of Plasmonic Core-Petal Nanostructures. https://app.cochat.ai/papers/10.1021/ja5085699
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Kumar, A., Kumar, S., Rhim, W.-K., Kim, G.-H., & Nam, J.-M. (2014). Oxidative Nanopeeling Chemistry-Based Synthesis and Photodynamic and Photothermal Therapeutic Applications of Plasmonic Core-Petal Nanostructures. Journal of the American Chemical Society. https://doi.org/10.1021/ja5085699

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