The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative
Abstract
By covalently connecting taxol with a motif that is prone to self-assemble, we successfully generate the precursor (5a), the hydrogelator (5b), and hydrogel of a taxol derivative without compromising the cytotoxic activity of the taxol. This approach promises a general method to create nanofibers of therapeutic molecules that have a dual role, as both the delivery vehicle and the drug itself.
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Cites
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Responsive Hydrogels from the Intramolecular Folding and Self-Assembly of a Designed Peptide
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Self-citation
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Soft Materials by Design: Unconventional Polymer Networks Give Extreme Properties
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Drug self-delivery systems for cancer therapy
Qin, S.-Y., Zhang, A.-Q., Cheng, S.-X., Rong, L., & Zhang, X.-Z. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2016.10.016 · Cited by 532
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Hydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems
Delgado-Pujol, E. J., Martínez, G., Casado-Jurado, D., Vázquez, J., León-Barberena, J., Rodríguez-Lucena, D., Torres, Y., Alcudia, A., & Begines, B. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17020215 · Cited by 216
Metadata
- Authors
- Gao, Y., Kuang, Y., Guo, Z.-F., Guo, Z., Krauss, I. J., & Xu, B.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-09-04
- Volume
- 131
- Issue
- 38
- Pages
- 13576-13577
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2013298034
- Cited by
- 403
- References
- 26
- FWCI
- 8.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gao, Y., Kuang, Y., Guo, Z.-F., Guo, Z., Krauss, I. J., & Xu, B. (2009). Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative. Journal of the American Chemical Society. https://doi.org/10.1021/ja904411z
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
