The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
An Allosteric Dual-DNAzyme Unimolecular Probe for Colorimetric Detection of Copper(II)
Open accessAbstract
An effective dual-DNAzyme-based unimolecular probe design employing intramolecular signal transduction is demonstrated. The probe is composed of three domains: a DNA-cleaving DNAzyme, a substrate, and an HRP-mimicking DNAzyme. When the probe meets its target, cleavage of the substrate by the DNA-cleaving DNAzyme activates the HRP-mimicking DNAzyme, producing a colorimetric signal. The Cu(2+)-dependent DNAzyme engineered to demonstrate this design revealed a sensitivity corresponding to 65 ppb, which is sufficient to detect Cu(2+) in drinking water. The new probe has excellent selectivity toward Cu(2+). This three-component design is simple and easy to engineer. It may provide the basis for future development of other nucleic acid-based probes for toxicological and environmental monitoring.
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Cites
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A Colorimetric Lead Biosensor Using DNAzyme-Directed Assembly of Gold Nanoparticles
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Cited by
Photonic Nanosensor for Colorimetric Detection of Metal Ions
Yetisen, A. K., Montelongo, Y., Qasim, M. M., Butt, H., Wilkinson, T. D., Monteiro, M. J., & Yun, S. H. (2015) · Analytical Chemistry · doi:10.1021/ac504274q · Cited by 94
Metadata
- Authors
- Yin, B.-C., Ye, B.-C., Tan, W., Wang, H., & Xie, C.-C.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-09-29
- Volume
- 131
- Issue
- 41
- Pages
- 14624-14625
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2092654845
- Cited by
- 287
- References
- 17
- FWCI
- 7.32
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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