The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Pathogen Inhibition by Multivalent Ligand Architectures
Abstract
Interfacial multivalent interactions at pathogen-cell interfaces can be competitively inhibited by multivalent scaffolds that prevent pathogen adhesion to the cells during the initial stages of infection. The lack of understanding of complex biological systems makes the design of an efficient multivalent inhibitor a toilsome task. Therefore, we have highlighted the main issues and concerns associated with blocking pathogen at interfaces, which are dependent on the nature and properties of both multivalent inhibitors and pathogens, such as viruses and bacteria. The challenges associated with different cores or carrier scaffolds of multivalent inhibitors are concisely discussed with selected examples.
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Citations
Cites
Foreign body reaction to biomaterials
Anderson, J. M., Rodriguez, A., & Chang, D. T. (2008) · Seminars in Immunology · doi:10.1016/j.smim.2007.11.004 · Cited by 5,138
Longmire, M., Choyke, P. L., & Kobayashi, H. (2008) · Nanomedicine · doi:10.2217/17435889.3.5.703 · Cited by 2,149
Bacterial Adhesion and Entry into Host Cells
Pizarro-Cerdá, J., & Cossart, P. (2006) · Cell · doi:10.1016/j.cell.2006.02.012 · Cited by 977
A review on macrophage responses to biomaterials
Xia, Z., & Triffitt, J. T. (2006) · Biomedical Materials · doi:10.1088/1748-6041/1/1/r01 · Cited by 418
Serrano-Gómez, D., Domínguez-Soto, A., Ancochea, J., Jimenez-Heffernan, J. A., Leal, J. A., & Corbí, A. L. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.9.5635 · Cited by 218
Cited by
Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic
Weiss, C., Carriere, M., Fusco, L., Capua, I., Regla-Nava, J. A., Pasquali, M., Scott, J. A., Vitale, F., Unal, M. A., Mattevi, C., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c03697 · Cited by 601
Metadata
- Authors
- Bhatia, S., Camacho, L. C., & Haag, R.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-07-07
- Volume
- 138
- Issue
- 28
- Pages
- 8654-8666
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2465561675
- Cited by
- 194
- References
- 5
- FWCI
- 10.99
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bhatia, S., Camacho, L. C., & Haag, R. (2016). Pathogen Inhibition by Multivalent Ligand Architectures. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.5b12950
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
