Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

Renal clearance of quantum dots

Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476 · see citing works

A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors

Hardman, R. C. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.8284 · Cited by 2,304 · see citing works

Nanoengineering of optical resonances

Oldenburg, S. J., Averitt, R. D., Westcott, S. L., & Halas, N. J. (1998) · Chemical Physics Letters · doi:10.1016/s0009-2614(98)00277-2 · Cited by 2,266 · see citing works

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

de Jong, W. H., Hagens, W. I., Krystek, P., Burger, M. C., Sips, A. J. A. M., & Geertsma, R. E. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2007.12.037 · Cited by 1,620 · see citing works

Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes)

Szoka, F. C., & Papahadjopoulos, D. (1980) · Annual Review of Biophysics and Bioengineering · doi:10.1146/annurev.bb.09.060180.002343 · Cited by 1,515 · see citing works

Recent advances in iron oxide nanocrystal technology for medical imaging☆

Corot, C., Robert, P., Idée, J., & Port, M. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.09.013 · Cited by 1,461 · see citing works

Gold nanoparticles: a new X-ray contrast agent

Hainfeld, J. F., Slatkin, D. N., Focella, T. M., & Smilowitz, H. M. (2006) · British Journal of Radiology · doi:10.1259/bjr/13169882 · Cited by 1,351 · see citing works

Dendrimers:

Malik, N., Wiwattanapatapee, R., Klopsch, R., Lorenz, K., Frey, H., Weener, J.-W., Meijer, E. W., Paulus, W., & Duncan, R. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00246-1 · Cited by 1,228 · see citing works

Noninvasive Imaging of Quantum Dots in Mice

Ballou, B. T., Lagerholm, B. C., Ernst, L. A., Bruchez, M. P., & Waggoner, A. S. (2003) · Bioconjugate Chemistry · doi:10.1021/bc034153y · Cited by 1,141 · see citing works

Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy

Liu, Z., Davis, C. R., Cai, W., He, L., Chen, X.-Y., & Dai, H. (2008) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.0707654105 · Cited by 1,097 · see citing works

Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers

Singh, R. N., Pantarotto, D., Lacerda, L., Pastorin, G., Klumpp, C., Prato, M., Bianco, A., & Kostarelos, K. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509009103 · Cited by 1,042 · see citing works

Gold Nanocages: Bioconjugation and Their Potential Use as Optical Imaging Contrast Agents

Chen, J., Saeki, F., Wiley, B. J., Cang, H., Cobb, M. J., Li, Z., Au, L., Zhang, H., Kimmey, M. B., Li, X. D., et al. (2005) · Nano Letters · doi:10.1021/nl047950t · Cited by 977 · see citing works

Fluorescence imaging in vivo: recent advances

Rao, J., Dragulescu‐Andrasi, A., & Yao, H. (2007) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2007.01.003 · Cited by 780 · see citing works

Dendrimer‐based metal chelates: A new class of magnetic resonance imaging contrast agents

Wiener, E. C., Brechbiel, M. W., Brothers, H. M., Magin, R. L., Gansow, O. A., Tomalia, D. A., & Lauterbur, P. C. (1994) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910310102 · Cited by 719 · see citing works

Biodistribution, Clearance, and Biocompatibility of Iron Oxide Magnetic Nanoparticles in Rats

Jain, T. K., Reddy, M. K., Morales, M. A., Leslie‐Pelecky, D. L., & Labhasetwar, V. D. (2008) · Molecular Pharmaceutics · doi:10.1021/mp7001285 · Cited by 709 · see citing works

Fate and behavior of liposomes in vivo: a review of controlling factors.

Senior, J. H. (1987) · PubMed · Cited by 592 · see citing works

Diffusion of Macromolecules and Virus-Like Particles in Human Cervical Mucus

Olmsted, S. S., Padgett, J. L., Yudin, A. I., Whaley, K. J., Moench, T. R., & Cone, R. A. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)75844-4 · Cited by 544 · see citing works

Metal Nanoshells

Hirsch, L. R., Gobin, A. M., Lowery, A. R., Tam, F., Drezek, R. A., Halas, N. J., & West, J. L. (2006) · Annals of Biomedical Engineering · doi:10.1007/s10439-005-9001-8 · Cited by 516 · see citing works

Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging

Tomalia, D. A., Reyna, L. A., & Svenson, S. (2007) · Biochemical Society Transactions · doi:10.1042/bst0350061 · Cited by 496 · see citing works

Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence

Cherukuri, P., Gannon, C. J., Leeuw, T. K., Schmidt, H., Smalley, R. E., Curley, S. A., & Weisman, R. B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609265103 · Cited by 490 · see citing works

Development of superparamagnetic nanoparticles for MRI: effect of particle size, charge and surface nature on biodistribution

Chouly, C., Pouliquen, D., Lucet, I., Jeune, J. J. L., & JALLET, P. (1996) · Journal of Microencapsulation · doi:10.3109/02652049609026013 · Cited by 468 · see citing works

What do we (need to) know about the kinetic properties of nanoparticles in the body?

Hagens, W. I., Oomen, A. G., de Jong, W. H., Cassee, F. R., & Sips, A. J. A. M. (2007) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2007.07.006 · Cited by 464 · see citing works

Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes.

Chonn, A., Semple, S. C., & Cullis, P. R. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)37026-7 · Cited by 461 · see citing works

Mesoporous Silica Nanospheres as Highly Efficient MRI Contrast Agents

Taylor-Pashow, K. M. L., Kim, J. S., Rieter, W. J., An, H., Lin, W., & Lin, W. (2008) · Journal of the American Chemical Society · doi:10.1021/ja710193c · Cited by 458 · see citing works

Nano-sized MRI contrast agents with dendrimer cores

Kobayashi, H., & Brechbiel, M. W. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.09.016 · Cited by 437 · see citing works

Structural determinants of glomerular permeability

Deen, W. M., Lazzara, M. J., & Myers, B. D. (2001) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.2001.281.4.f579 · Cited by 415 · see citing works

First Soluble M@C60 Derivatives Provide Enhanced Access to Metallofullerenes and Permit in Vivo Evaluation of Gd@C60[C(COOH)2]10 as a MRI Contrast Agent

Bolskar, R. D., Benedetto, A. F., Husebo, L. O., Price, R. E., Jackson, E. F., Wallace, S., Wilson, L. J., & Alford, J. M. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0340984 · Cited by 401 · see citing works

Gum Arabic as a Phytochemical Construct for the Stabilization of Gold Nanoparticles: In Vivo Pharmacokinetics and X‐ray‐Contrast‐Imaging Studies

Kattumuri, V., Katti, K. K., Bhaskaran, S., Boote, E., Casteel, S. W., Fent, G. M., Robertson, D. J., Chandrasekhar, M., Kannan, R., & Katti, K. V. (2007) · Small · doi:10.1002/smll.200600427 · Cited by 380 · see citing works

Superparamagnetic Agents in Magnetic Resonance Imaging: Physicochemical Characteristics and Clinical Applications A Review

Bonnemain, B. (1998) · Journal of drug targeting · doi:10.3109/10611869808997890 · Cited by 372 · see citing works

The role of surface charge in the activation of the classical and alternative pathways of complement by liposomes

Chonn, A., Cullis, P. R., & Devine, D. V. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.146.12.4234 · Cited by 367 · see citing works

Therapeutic antibody fragments with prolonged in vivo half-lives

Chapman, A. P., Antoniw, P., Spitali, M., West, S. M., Stephens, S., & King, D. (1999) · Nature Biotechnology · doi:10.1038/11717 · Cited by 350 · see citing works

Pharmacokinetics of Nanoscale Quantum Dots: In Vivo Distribution, Sequestration, and Clearance in the Rat

Fischer, H. C., Liu, L., Pang, K. S., & Chan, W. C. W. (2006) · Advanced Functional Materials · doi:10.1002/adfm.200500529 · Cited by 347 · see citing works

Sentinel Lymph Node Imaging Using Quantum Dots in Mouse Tumor Models

Ballou, B. T., Ernst, L. A., Andreko, S. K., Harper, T. F., Fitzpatrick, J. A. J., Waggoner, A. S., & Bruchez, M. P. (2007) · Bioconjugate Chemistry · doi:10.1021/bc060261j · Cited by 344 · see citing works

Water-Soluble Gadofullerenes: Toward High-Relaxivity, pH-Responsive MRI Contrast Agents

Tóth, É., Bolskar, R. D., Borel, A., González, G., Helm, L., Merbach, A. E., Sitharaman, B., & Wilson, L. J. (2004) · Journal of the American Chemical Society · doi:10.1021/ja044688h · Cited by 341 · see citing works

Preclinical Safety and Pharmacokinetic Profile of Ferumoxtran-10, an Ultrasmall Superparamagnetic Iron Oxide Magnetic Resonance Contrast Agent

Bourrinet, P., Bengele, H. H., Bonnemain, B., Dencausse, A., Idée, J., Jacobs, P. M., & Lewis, J. M. (2006) · Investigative Radiology · doi:10.1097/01.rli.0000197669.80475.dd · Cited by 340 · see citing works

Liposome Clearance

Ishida, T., Harashima, H., & Kiwada, H. (2002) · Bioscience Reports · doi:10.1023/a:1020134521778 · Cited by 329 · see citing works

Persistent Tissue Kinetics and Redistribution of Nanoparticles, Quantum Dot 705, in Mice: ICP-MS Quantitative Assessment

Yang, R. S. H., Chang, L. W., Wu, J.-P., Tsai, M., Wang, H., Kuo, Y.-C., Yeh, T., Yang, C. S., & Lin, P. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10290 · Cited by 314 · see citing works

In vivo studies of fullerene-based materials using endohedral metallofullerene radiotracers

Cagle, D. W., Kennel, S. J., Mirzadeh, S., Alford, J. M., & Wilson, L. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.9.5182 · Cited by 303 · see citing works

Pharmacokinetic Consequences of Pegylation

Hamidi, M., Azadi, A., & Rafiei, P. (2006) · Drug Delivery · doi:10.1080/10717540600814402 · Cited by 303 · see citing works

Enhanced Hepatic Uptake of Liposomes Through Complement Activation Depending on the Size of Liposomes

Harashima, H., Sakata, K., Funato, K., & Kiwada, H. (1994) · Pharmaceutical Research · doi:10.1023/a:1018965121222 · Cited by 285 · see citing works

Macromolecular MRI Contrast Agents with Small Dendrimers: Pharmacokinetic Differences between Sizes and Cores

Kobayashi, H., Kawamoto, S., Jo, S.-K., Bryant, H. L., Brechbiel, M. W., & Star, R. A. (2003) · Bioconjugate Chemistry · doi:10.1021/bc025633c · Cited by 262 · see citing works

Lanthanoid Endohedral Metallofullerenols for MRI Contrast Agents

Kato, H., Kanazawa, Y., Okumura, M., Taninaka, A., Yokawa, T., & Shinohara, H. (2003) · Journal of the American Chemical Society · doi:10.1021/ja027555+ · Cited by 261 · see citing works

Controlled synthesis and quantum-size effect in gold-coated nanoparticles

Zhou, H., Honma, I., Komiyama, H., & Haus, J. W. (1994) · Physical review. B, Condensed matter · doi:10.1103/physrevb.50.12052 · Cited by 251 · see citing works

Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent

Enochs, W. S., Harsh, G. R., Hochberg, F. H., & Weissleder, R. (1999) · Journal of Magnetic Resonance Imaging · doi:10.1002/(sici)1522-2586(199902)9:2 · Cited by 247 · see citing works

Hepatic cellular distribution and degradation of iron oxide nanoparticles following single intravenous injection in rats: implications for magnetic resonance imaging

Briley-Saebo, K. C., Bj�rnerud, A., Grant, D., Ahlstrom, H., Berg, T., & Kindberg, G. M. (2004) · Cell and Tissue Research · doi:10.1007/s00441-004-0884-8 · Cited by 235 · see citing works

In Vitro and in Vivo Imaging Studies of a New Endohedral Metallofullerene Nanoparticle

Fatouros, P. P., Corwin, F. D., Chen, Z., Broaddus, W. C., Tatum, J. L., Kettenmann, B., Ge, Z., Gibson, H. W., Russ, J. L., Leonard, A. P., et al. (2006) · Radiology · doi:10.1148/radiol.2403051341 · Cited by 208 · see citing works

microPET-Based Biodistribution of Quantum Dots in Living Mice

Schipper, M. L., Cheng, Z., Lee, S., Bentolila, L. A., Iyer, G., Rao, J., Chen, X. S., Wu, A. M., Weiss, S., & Gambhir, S. S. (2007) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.040071 · Cited by 203 · see citing works

FloDots: luminescent nanoparticles

Yao, G., Wang, L., Wu, Y., Smith, J., Xu, J., Zhao, W., Lee, E., & Tan, W. (2006) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-006-0452-z · Cited by 158 · see citing works

Imaging of the lymphatic system: new horizons

Barrett, T., Choyke, P. L., & Kobayashi, H. (2006) · Contrast Media & Molecular Imaging · doi:10.1002/cmmi.116 · Cited by 148 · see citing works

A gel-membrane model of glomerular charge and size selectivity in series

Ohlson, M., Sörensson, J., & Haraldsson, B. S. (2001) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.2001.280.3.f396 · Cited by 145 · see citing works

Dendrimer-Based Nanosized MRI Contrast Agents

Kobayashi, H., & Brechbiel, M. W. (2004) · Current Pharmaceutical Biotechnology · doi:10.2174/1389201043376571 · Cited by 142 · see citing works

Advances and challenges of nanotechnology-based drug delivery systems

Jiang, W., Kim, B. Y. S., Rutka, J. T., & Chan, W. C. W. (2007) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.4.6.621 · Cited by 139 · see citing works

Pharmacokinetics and enhancement patterns of macromolecular MR contrast agents with various sizes of polyamidoamine dendrimer cores

Sato, N., Kobayashi, H., Hiraga, A., Saga, T., Togashi, K., Konishi, J., & Brechbiel, M. W. (2001) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1314 · Cited by 130 · see citing works

Evaluation of the in Vivo Biodistribution of Indium-111 and Yttrium-88 Labeled Dendrimer-1B4M-DTPA and Its Conjugation with Anti-Tac Monoclonal Antibody

Kobayashi, H., Wu, C., Kim, M.-K., Paik, C. H., Carrasquillo, J. A., & Brechbiel, M. W. (1998) · Bioconjugate Chemistry · doi:10.1021/bc980091d · Cited by 120 · see citing works

Bio-Applications of Nanoparticles

Chan, W. C. W. (2007) · Advances in experimental medicine and biology · doi:10.1007/978-0-387-76713-0 · Cited by 117 · see citing works

Magnetic Resonance Angiography With Gadomer-17

Dong, Q., Hurst, D. R., WEINMANN, H. J., Chenevert, T. L., Londy, F. J., & Prince, M. R. (1998) · Investigative Radiology · doi:10.1097/00004424-199809000-00026 · Cited by 116 · see citing works

In Vivo Performance of a Liposomal Vascular Contrast Agent for CT and MR-Based Image Guidance Applications

Zheng, J., Liu, J., Dunne, M., Jaffray, D. A., & Allen, C. J. (2007) · Pharmaceutical Research · doi:10.1007/s11095-006-9220-1 · Cited by 115 · see citing works

Genetically engineered tetravalent single-chain Fv of the pancarcinoma monoclonal antibody CC49: improved biodistribution and potential for therapeutic application.

Goel, A., Colcher, D. M., Baranowska‐Kortylewicz, J., Augustine, S. C., Booth, B. J. M., Pavlínková, G., & Batra, S. K. (2000) · PubMed · Cited by 104 · see citing works

Contribution of complement system on destabilization of liposomes composed of hydrogenated egg phosphatidylcholine in rat fresh plasma

Funato, K., Yoda, R., & Kiwada, H. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90087-3 · Cited by 102 · see citing works

MR properties of rat sciatic nerve following trauma

Stanisz, G. J., Midha, R., Munro, C. A., & Henkelman, R. M. (2001) · Magnetic Resonance in Medicine · doi:10.1002/1522-2594(200103)45:3 · Cited by 95 · see citing works

Polyamine dendrimer‐based MRI contrast agents for functional kidney imaging to diagnose acute renal failure

Kobayashi, H., Jo, S., Kawamoto, S., Yasuda, H., Hu, X., Knopp, M. V., Brechbiel, M. W., Choyke, P. L., & Star, R. A. (2004) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.20147 · Cited by 89 · see citing works

The pharmacokinetic characteristics of glycolated humanized anti-Tac Fabs are determined by their isoelectric points.

Kobayashi, H., Le, N., Kim, I. S., Kim, M. K., Pie, J.-E., Drumm, D., Paik, D. S., Waldmann, T. A., Paik, C. H., & Carrasquillo, J. A. (1999) · PubMed · Cited by 73 · see citing works

Gadofullerenes as nanoscale magnetic labels for cellular MRI

Sitharaman, B., Tran, L. A., Pham, Q. P., Bolskar, R. D., Muthupillai, R., Flamm, S. D., Mikos, A. G., & Wilson, L. J. (2007) · Contrast Media & Molecular Imaging · doi:10.1002/cmmi.140 · Cited by 72 · see citing works

Gadolinium(III)-based blood-pool contrast agents for magnetic resonance imaging: status and clinical potential

Mohs, A. M., & Lu, Z. (2007) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.4.2.149 · Cited by 69 · see citing works

L-lysine effectively blocks renal uptake of 125I- or 99mTc-labeled anti-Tac disulfide-stabilized Fv fragment.

Kobayashi, H., Yoo, T. M., Kim, I. S., Kim, M.-K., Le, N., Webber, K. O., Pastan, I. H., Paik, C. H., Eckelman, W. C., & Carrasquillo, J. A. (1996) · PubMed · Cited by 66 · see citing works

Pharmacokinetic Behavior of Gadoteridol Injection

McLachlan, S. J., Eaton, S., & Simone, D. N. D. (1992) · Investigative Radiology · doi:10.1097/00004424-199208001-00004 · Cited by 66 · see citing works

Extracellular biodegradable macromolecular gadolinium(III) complexes for MRI

Lu, Z., Parker, D. L., Goodrich, K. C., Wang, X., Dalle, J. G., & Buswell, H. R. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10656 · Cited by 63 · see citing works

Regulation of vascular endothelial cell barrier function and cytoskeleton structure by protein phosphatases of the PPP family

Csoŕtos, C., Kolosova, I. A., & Verin, A. D. (2007) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00120.2007 · Cited by 62 · see citing works

Superparamagnetic agents: Physicochemical characteristics and preclinical imaging evaluation

Benderbous, S., Corot, C., Jacobs, P. M., & Bonnemain, B. (1996) · Academic Radiology · doi:10.1016/s1076-6332(96)80560-5 · Cited by 56 · see citing works

Contrast‐enhanced MRI with new biodegradable macromolecular Gd(III) complexes in tumor‐bearing mice

Zong, Y., Wang, X., Goodrich, K. C., Mohs, A. M., Parker, D. L., & Lu, Z. (2005) · Magnetic Resonance in Medicine · doi:10.1002/mrm.20402 · Cited by 55 · see citing works

Synergistic Effect Between Size and Cholesterol Content in the Enhanced Hepatic Uptake Clearance of Liposomes Through Complement Activation in Rats

Harashima, H., HUONG, T. M., Ishida, T., Manabe, Y., Matsuo, H., & Kiwada, H. (1996) · Pharmaceutical Research · doi:10.1023/a:1016401025747 · Cited by 50 · see citing works

Pharmacokinetics, Biodistribution and Contrast Enhanced MR Blood Pool Imaging of Gd-DTPA Cystine Copolymers and Gd-DTPA Cystine Diethyl Ester Copolymers in a Rat Model

Feng, Y., Zong, Y., Ke, T., Jeong, E., Parker, D. L., & Lu, Z. (2006) · Pharmaceutical Research · doi:10.1007/s11095-006-9028-z · Cited by 44 · see citing works

Hepatology, Principles and Practice: History, Morphology, Biochemistry, Diagnostics, Clinic, Therapy

Kuntz, E., & Kuntz, H.-D. (2001) · Springer eBooks · doi:10.1007/3-540-28977-1 · Cited by 36 · see citing works

SENTINEL NODE STAGING OF EARLY BREAST CANCER USING LYMPHOSCINTIGRAPHY AND THE INTRAOPERATIVE GAMMA DETECTING PROBE

Alazraki, N. P., Styblo, T. M., Grant, S. F., Cohen, C., Larsen, T., Waldrop, S. M., & Aarsvold, J. N. (2001) · Radiologic Clinics of North America · doi:10.1016/s0033-8389(05)70322-5 · Cited by 31 · see citing works

Plasma and renal clearance of iohexol–a study on the reproducibility of a method for the glomerular filtration rate

Arvidsson, A., & Hedman, A. (1990) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365519009091069 · Cited by 29 · see citing works

The concentration-dependent disposition and kinetics of inulin

Prescott, L. F., McAuslane, J. A. N., & Freestone, S. H. (1991) · European Journal of Clinical Pharmacology · doi:10.1007/bf00279982 · Cited by 28 · see citing works

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Blanco, E., Shen, H., & Ferrari, M. (2015) · Nature Biotechnology · doi:10.1038/nbt.3330 · Cited by 7,002 · see citing works

The golden age: gold nanoparticles for biomedicine

Dreaden, E. C., Alkilany, A. M., Huang, X., Murphy, C. J., & El‐Sayed, M. A. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15237h · Cited by 3,572 · see citing works

Delivering nanomedicine to solid tumors

Jain, R. K., & Stylianopoulos, T. (2010) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2010.139 · Cited by 3,196 · see citing works

Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery

Tang, F., Li, L., & Chen, D. (2012) · Advanced Materials · doi:10.1002/adma.201104763 · Cited by 2,843 · see citing works

Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics

Chen, G., Qiu, H., Prasad, P. N., & Chen, X. S. (2014) · Chemical Reviews · doi:10.1021/cr400425h · Cited by 2,704 · see citing works

New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging

Kobayashi, H., Ogawa, M., Alford, R. E., Choyke, P. L., & Urano, Y. (2009) · Chemical Reviews · doi:10.1021/cr900263j · Cited by 2,205 · see citing works

Engineered Nanoparticles for Drug Delivery in Cancer Therapy

Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164 · see citing works

Nanoparticles for photothermal therapies

Jaque, D., Maestro, L. M., del Rosal, B., Haro‐González, P., Benayas, A., Plaza, J., Rodríguez, E. M., & Solé, J. G. (2014) · Nanoscale · doi:10.1039/c4nr00708e · Cited by 1,947 · see citing works

Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging

Omid Veiseh, A., Gunn, J., & Zhang, M. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.002 · Cited by 1,836 · see citing works

Recent Progress in Rare Earth Micro/Nanocrystals: Soft Chemical Synthesis, Luminescent Properties, and Biomedical Applications

Gai, S., Li, C., Yang, P., & Lin, J. (2013) · Chemical Reviews · doi:10.1021/cr4001594 · Cited by 1,464 · see citing works

Progress in applications of magnetic nanoparticles in biomedicine

Pankhurst, Q. A., Thanh, N. T. K., Jones, S. K., & Dobson, J. (2009) · Journal of Physics D Applied Physics · doi:10.1088/0022-3727/42/22/224001 · Cited by 1,459 · see citing works

Nanoparticle uptake: The phagocyte problem

Gustafson, H. H., Holt‐Casper, D., Grainger, D. W., & Ghandehari, H. (2015) · Nano Today · doi:10.1016/j.nantod.2015.06.006 · Cited by 1,424 · see citing works

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

Zhang, Y.-N., Poon, W., Tavares, A. J., McGilvray, I. D., & Chan, W. C. W. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.01.020 · Cited by 1,358 · see citing works

Diverse Applications of Nanomedicine

Pelaz, B., Alexiou, C., Alvarez-Puebla, R. A., Alves, F., Andrews, A. M., Ashraf, S., Balogh, L. P., Ballerini, L., Bestetti, A., Brendel, C., et al. (2017) · ACS Nano · doi:10.1021/acsnano.6b06040 · Cited by 1,350 · see citing works

Gold Nanomaterials at Work in Biomedicine

Yang, X., Yang, M., Pang, B., Vara, M., & Younan Xia, A. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00193 · Cited by 1,169 · see citing works

A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications

James, M. L., & Gambhir, S. S. (2012) · Physiological Reviews · doi:10.1152/physrev.00049.2010 · Cited by 1,145 · see citing works

Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents

Sun, Z., Xie, H., Tang, S., Yu, X., Guo, Z., Shao, J., Zhang, H., Huang, H., Wang, H., & Chu, P. K.-H. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201506154 · Cited by 1,135 · see citing works

Targeting Strategies for Tissue-Specific Drug Delivery

Zhao, Z., Ukidve, A., Kim, J., & Mitragotri, S. (2020) · Cell · doi:10.1016/j.cell.2020.02.001 · Cited by 1,114 · see citing works

Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

Nakamura, Y., Mochida, A., Choyke, P. L., & Kobayashi, H. (2016) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.6b00437 · Cited by 1,107 · see citing works

The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy

Doane, T. L., & Burda, C. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15260f · Cited by 1,100 · see citing works

The Enhanced Permeability and Retention (EPR) Effect: The Significance of the Concept and Methods to Enhance Its Application

Wu, J. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11080771 · Cited by 1,030 · see citing works

Improving conventional enhanced permeability and retention (EPR) effects; what is the appropriate target?

Kobayashi, H., Watanabe, R., & Choyke, P. L. (2014) · Theranostics · doi:10.7150/thno.7193 · Cited by 996 · see citing works

Compound Copper Chalcogenide Nanocrystals

Coughlan, C., Ibáñez, M., Dobrozhan, O., Singh, A., Cabot, A., & Ryan, K. M. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00376 · Cited by 930 · see citing works

Nanoparticle vaccines

Zhao, L., Seth, A., Wibowo, N., Zhao, C., Mitter, N., Yu, C., & Middelberg, A. P. J. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.11.069 · Cited by 922 · see citing works

Gold Nanoparticles for Photothermal Cancer Therapy

Vines, J. B., Yoon, J.-H., Ryu, N.-E., Lim, D.-J., & Park, H. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00167 · Cited by 910 · see citing works

Toxicology of nanoparticles

Elsaesser, A., & Howard, C. V. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.09.001 · Cited by 904 · see citing works

Lanthanide-doped luminescent nanoprobes: controlled synthesis, optical spectroscopy, and bioapplications

Liu, Y., Tu, D., Zhu, H., & Chen, X. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60060b · Cited by 902 · see citing works

Clearance Pathways and Tumor Targeting of Imaging Nanoparticles

Yu, M., & Zheng, J. (2015) · ACS Nano · doi:10.1021/acsnano.5b01320 · Cited by 888 · see citing works

Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents

Sun, Z., Xie, H., Tang, S., Yu, X., Guo, Z., Shao, J., Zhang, H., Huang, H., Wang, H., & Chu, P. K.-H. (2015) · Angewandte Chemie · doi:10.1002/ange.201506154 · Cited by 881 · see citing works

In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles

Arami, H., Khandhar, A., Liggitt, D., & Krishnan, K. M. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00541h · Cited by 830 · see citing works

Functional Near Infrared-Emitting Cr 3+ /Pr 3+ Co-Doped Zinc Gallogermanate Persistent Luminescent Nanoparticles with Superlong Afterglow for in Vivo Targeted Bioimaging

Abdukayum, A., Chen, J., Zhao, Q., & Yan, X. (2013) · Journal of the American Chemical Society · doi:10.1021/ja404243v · Cited by 710 · see citing works

Application of zirconium MOFs in drug delivery and biomedicine

Lázaro, I. A., & Forgan, R. S. (2018) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2018.09.009 · Cited by 682 · see citing works

Nanomaterial cytotoxicity is composition, size, and cell type dependent

Sohaebuddin, S. K., Thevenot, P., Baker, D. W., Eaton, J. W., & Tang, L. (2010) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-7-22 · Cited by 676 · see citing works

Size Matters: Gold Nanoparticles in Targeted Cancer Drug Delivery

Dreaden, E. C., Austin, L. A., Mackey, M. A., & El‐Sayed, M. A. (2012) · Therapeutic Delivery · doi:10.4155/tde.12.21 · Cited by 656 · see citing works

Applications of nanoparticles in biomedical imaging

Han, X., Xu, K., Taratula, O. R., & Farsad, K. (2018) · Nanoscale · doi:10.1039/c8nr07769j · Cited by 638 · see citing works

Ultrasmall Monodisperse NaYF 4 :Yb 3+ /Tm 3+ Nanocrystals with Enhanced Near-Infrared to Near-Infrared Upconversion Photoluminescence

Chen, G., Ohulchanskyy, T. Y., Kumar, R., Ågren, H., & Prasad, P. N. (2010) · ACS Nano · doi:10.1021/nn100457j · Cited by 632 · see citing works

Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents

Busquets, M. A., Estelrich, J., & Sánchez‐Martín, M. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s76501 · Cited by 632 · see citing works

Lab on upconversion nanoparticles: optical properties and applications engineering via designed nanostructure

Li, X., Zhang, F., & Zhao, D. (2014) · Chemical Society Reviews · doi:10.1039/c4cs00163j · Cited by 617 · see citing works

Beating cancer in multiple ways using nanogold

Dreaden, E. C., Mackey, M. A., Huang, X., Kang, B., & El‐Sayed, M. A. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00180e · Cited by 607 · see citing works

Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics

Tang, W., Fan, W., Lau, J., Deng, L., Shen, Z., & Chen, X. S. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00805a · Cited by 606 · see citing works

Surface Engineering of Iron Oxide Nanoparticles for Targeted Cancer Therapy

Kievit, F. M., & Zhang, M. (2011) · Accounts of Chemical Research · doi:10.1021/ar2000277 · Cited by 606 · see citing works

Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies

Chauhan, V. P., Stylianopoulos, T., Boucher, Y., & Jain, R. K. (2011) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-061010-114300 · Cited by 597 · see citing works

Glomerular barrier behaves as an atomically precise bandpass filter in a sub-nanometre regime

Du, B., Jiang, X., Das, A., Zhou, Q., Yu, M., Jin, R. M., & Zheng, J. (2017) · Nature Nanotechnology · doi:10.1038/nnano.2017.170 · Cited by 591 · see citing works

Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice

Lasagna‐Reeves, C. A., Gonzalez-Romero, D., Barria, M. A., Olmedo, I., Clos, A. L., Ramanujam, V. M. S., Urayama, A., Vergara, L. A., Kogan, M. J., & Soto, C. A. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.02.046 · Cited by 584 · see citing works

In VivoBiodistribution of Nanoparticles

Almeida, J. P. M., Chen, A. L., Foster, A. E., & Drezek, R. A. (2011) · Nanomedicine · doi:10.2217/nnm.11.79 · Cited by 582 · see citing works

Surface Modifications of Nanoparticles for Stability in Biological Fluids

Guerrini, L., Álvarez‐Puebla, R. A., & Pérez, N. P. (2018) · Materials · doi:10.3390/ma11071154 · Cited by 577 · see citing works

Nanotechnology-based combinational drug delivery: an emerging approach for cancer therapy

Parhi, P., Mohanty, C., & Sahoo, S. K. (2012) · Drug Discovery Today · doi:10.1016/j.drudis.2012.05.010 · Cited by 573 · see citing works

Two-photon excitation nanoparticles for photodynamic therapy

Shen, Y., Shuhendler, A. J., Ye, D., Xu, J., & Chen, H. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00442c · Cited by 569 · see citing works

Emerging concepts in dendrimer‐based nanomedicine: from design principles to clinical applications

Kannan, R., Nance, E. A., Kannan, S., & Tomalia, D. A. (2014) · Journal of Internal Medicine · doi:10.1111/joim.12280 · Cited by 548 · see citing works

In Vivo Biodistribution and Toxicology of Carboxylated Graphene Quantum Dots

Nurunnabi, M., Khatun, Z., Huh, K. M., Park, S. Y., Lee, D. Y., Cho, K.-J., & Lee, Y.-K. (2013) · ACS Nano · doi:10.1021/nn402043c · Cited by 546 · see citing works

Ligand-targeted liposome design: challenges and fundamental considerations

Noble, G. T., Stefanick, J. F., Ashley, J. D., Kiziltepe, T., & Bilgiçer, B. (2013) · Trends in biotechnology · doi:10.1016/j.tibtech.2013.09.007 · Cited by 543 · see citing works

Metabolism of Nanomaterials in Vivo: Blood Circulation and Organ Clearance

Wang, B., He, X. B., Zhang, Z., Zhao, Y., & Feng, W. (2012) · Accounts of Chemical Research · doi:10.1021/ar2003336 · Cited by 534 · see citing works

Gold Nanoparticles for Nucleic Acid Delivery

Ding, Y., Jiang, Z., Saha, K., Kim, C. S., Kim, S. T., Landis, R. F., & Rotello, V. M. (2014) · Molecular Therapy · doi:10.1038/mt.2014.30 · Cited by 521 · see citing works

Mechanisms of drug release in nanotherapeutic delivery systems

Wong, P. T., & Choi, S. K. (2015) · Chemical Reviews · doi:10.1021/cr5004634 · Cited by 507 · see citing works

The Use of Alternative Strategies for Enhanced Nanoparticle Delivery to Solid Tumors

Izci, M., Maksoudian, C., Manshian, B. B., & Soenen, S. J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00779 · Cited by 506 · see citing works

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

Grossen, P., Witzigmann, D., Sieber, S., & Huwyler, J. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.05.028 · Cited by 503 · see citing works

Biodistribution of extracellular vesicles following administration into animals: A systematic review

Kang, M., Jordan, V., Blenkiron, C., & Chamley, L. (2021) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12085 · Cited by 498 · see citing works

Applications of nanoparticles for diagnosis and therapy of cancer

Baetke, S. C., Lammers, T., & Kiessling, F. M. (2015) · British Journal of Radiology · doi:10.1259/bjr.20150207 · Cited by 497 · see citing works

Anti-Stokes shift luminescent materials for bio-applications

Zhu, X., Su, Q., Feng, W., & Li, F. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00415f · Cited by 497 · see citing works

Luminescent Gold Nanoparticles with Efficient Renal Clearance

Zhou, C., Long, M., Qin, Y., Sun, X., & Zheng, J. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007321 · Cited by 491 · see citing works

Crossing the Blood-Brain Barrier: Advances in Nanoparticle Technology for Drug Delivery in Neuro-Oncology

Hersh, A. M., Alomari, S., & Tyler, B. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084153 · Cited by 478 · see citing works

Nanobodies as therapeutics: big opportunities for small antibodies

Steeland, S., Vandenbroucke, R. E., & Libert, C. (2016) · Drug Discovery Today · doi:10.1016/j.drudis.2016.04.003 · Cited by 470 · see citing works

Biodistribution, Clearance, and Long‐Term Fate of Clinically Relevant Nanomaterials

Bourquin, J., Milosevic, A. M., Hauser, D., Lehner, R., Blank, F., Petri‐Fink, A., & Rothen‐Rutishauser, B. (2018) · Advanced Materials · doi:10.1002/adma.201704307 · Cited by 470 · see citing works

Behavior and Toxicity of Graphene and Its Functionalized Derivatives in Biological Systems

Yang, K., Li, Y., Tan, X., Peng, R., & Liu, Z. (2012) · Small · doi:10.1002/smll.201201417 · Cited by 464 · see citing works

Magnetic Nanoparticles in Cancer Theranostics

Gobbo, O. L., Sjaastad, K., Radomski, M. W., Volkov, Y., & Prina‐Mello, A. (2015) · Theranostics · doi:10.7150/thno.11544 · Cited by 462 · see citing works

DNA Vaccines—How Far From Clinical Use?

Hobernik, D., & Bros, M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19113605 · Cited by 457 · see citing works

Nanoparticles for biomedical imaging

Nune, S. K., Gunda, P., Thallapally, P. K., Lin, Y., Forrest, M. L., & Berkland, C. J. (2009) · Expert Opinion on Drug Delivery · doi:10.1517/17425240903229031 · Cited by 450 · see citing works

Superparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challenges

Laurent, S., Saei, A. A., Behzadi, S., Panahifar, A., & Mahmoudi, M. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2014.924501 · Cited by 445 · see citing works

Gold nanoparticles for cancer radiotherapy: a review

Haume, K., Rosa, S., Grellet, S., Śmiałek, M. A., Butterworth, K. T., Solov’yov, A. V., Prise, K. M., Golding, J. P., & Mason, N. J. (2016) · Cancer Nanotechnology · doi:10.1186/s12645-016-0021-x · Cited by 446 · see citing works

Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy

Dong, Z., Feng, L., Chao, Y., Hao, Y., Chen, M., Gong, F., Han, X., Zhang, R., Cheng, L., & Liu, Z. (2018) · Nano Letters · doi:10.1021/acs.nanolett.8b03905 · Cited by 437 · see citing works

Photon‐Upconverting Nanoparticles for Optical Encoding and Multiplexing of Cells, Biomolecules, and Microspheres

Gorris, H. H., & Wolfbeis, O. S. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201208196 · Cited by 436 · see citing works

Magnetite nanoparticles for medical MR imaging

Stephen, Z. R., Kievit, F. M., & Zhang, M. (2011) · Materials Today · doi:10.1016/s1369-7021(11)70163-8 · Cited by 434 · see citing works

Paradoxical glomerular filtration of carbon nanotubes

Ruggiero, A., Villa, C. H., Bander, E. D., Rey, D. A., Bergkvist, M., Batt, C. A., Manova-Todorova, K. O., Deen, W. M., Scheinberg, D. A., & McDevitt, M. R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0913667107 · Cited by 426 · see citing works

Biomedical Applications of Photoacoustic Imaging with Exogenous Contrast Agents

Luke, G. P., Yeager, D., & Emelianov, S. (2011) · Annals of Biomedical Engineering · doi:10.1007/s10439-011-0449-4 · Cited by 418 · see citing works

Non-viral delivery systems for CRISPR/Cas9-based genome editing: challenges and opportunities

Li, L., Hu, S., & Chen, X. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.04.031 · Cited by 415 · see citing works

Advances in carbon dots: from the perspective of traditional quantum dots

Liu, Y., Huang, H., Cao, W., Mao, B., Liu, Y., & Kang, Z. (2020) · Materials Chemistry Frontiers · doi:10.1039/d0qm00090f · Cited by 415 · see citing works

Size-Tunable, Ultrasmall NaGdF4 Nanoparticles: Insights into Their T1 MRI Contrast Enhancement

Johnson, N. J. J., Oakden, W., Stanisz, G. J., Prosser, R. S., & van Veggel, F. C. J. M. (2011) · Chemistry of Materials · doi:10.1021/cm201297x · Cited by 414 · see citing works

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

Erdbrügger, U., Blijdorp, C. J., Bijnsdorp, I. V., Borràs, F. E., Burger, D. E., Bussolati, B., Byrd, J. B., Clayton, A., Dear, J. W., Falcón‐Pérez, J. M., et al. (2021) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12093 · Cited by 413 · see citing works

Supramolecular cancer nanotheranostics

Zhou, J., Rao, L., Yu, G., Cook, T. R., Chen, X., & Huang, F. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00011f · Cited by 411 · see citing works

Rational engineering of physicochemical properties of nanomaterials for biomedical applications with nanotoxicological perspectives

Navya, P. N., & Daima, H. K. (2016) · Nano Convergence · doi:10.1186/s40580-016-0064-z · Cited by 404 · see citing works

Noble Metal Nanomaterials for NIR‐Triggered Photothermal Therapy in Cancer

Lv, Z., He, S., Wang, Y., & Zhu, X. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202001806 · Cited by 399 · see citing works

A repertoire of biomedical applications of noble metal nanoparticles

Azharuddin, M., Zhu, G. H., Das, D., Özgür, E., Uzun, L., Turner, A. P. F., & Patra, H. K. (2019) · Chemical Communications · doi:10.1039/c9cc01741k · Cited by 397 · see citing works

Anti-oxidant effect of gold nanoparticles restrains hyperglycemic conditions in diabetic mice

BarathManiKanth, S., Kalishwaralal, K., Sriram, M. I., Pandian, S. R. K., Youn, H., Eom, S.-H., & Gurunathan, S. (2010) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-8-16 · Cited by 386 · see citing works

Nanoemulsions for drug delivery

Wilson, R. J., Li, Y., Yang, G., & Zhao, C. (2021) · Particuology · doi:10.1016/j.partic.2021.05.009 · Cited by 378 · see citing works

Tailored functionalization of iron oxide nanoparticles for MRI, drug delivery, magnetic separation and immobilization of biosubstances

Holá, K., Marková, Z., Zoppellaro, G., Tuček, J., & Zbořil, R. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.02.003 · Cited by 372 · see citing works

Magnetic Particle Imaging: A Novel in Vivo Imaging Platform for Cancer Detection

Yu, E. Y., Bishop, M. D., Zheng, B., Ferguson, R. M., Khandhar, A. P., Kemp, S. J., Krishnan, K. M., Goodwill, P. W., & Conolly, S. (2017) · Nano Letters · doi:10.1021/acs.nanolett.6b04865 · Cited by 371 · see citing works

Nanoparticles for Biomedical Imaging: Fundamentals of Clinical Translation

Choi, H. S., & Frangioni, J. V. (2010) · Molecular Imaging · doi:10.2310/7290.2010.00031 · Cited by 354 · see citing works

Renal clearable inorganic nanoparticles: a new frontier of bionanotechnology

Liu, J., Yu, M., Zhou, C., & Zheng, J. (2013) · Materials Today · doi:10.1016/j.mattod.2013.11.003 · Cited by 352 · see citing works

Physiologically Based Pharmacokinetic Modeling of Nanoparticles

Li, M., Al‐Jamal, K. T., Kostarelos, K., & Reineke, J. (2010) · ACS Nano · doi:10.1021/nn1018818 · Cited by 351 · see citing works

Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing

Zhigaltsev, I. V., Belliveau, N. M., Hafez, I. M., Leung, A. K. K., Huft, J., Hansen, C. L., & Cullis, P. R. (2012) · Langmuir · doi:10.1021/la204833h · Cited by 346 · see citing works

Nanoparticulate X-ray Computed Tomography Contrast Agents: From Design Validation to in Vivo Applications

Liu, Y., Ai, K., & Lu, L. (2012) · Accounts of Chemical Research · doi:10.1021/ar300150c · Cited by 347 · see citing works

Upconverting and NIR emitting rare earth based nanostructures for NIR-bioimaging

Hemmer, E., Venkatachalam, N., Hyodo, H., Hattori, A., Ebina, Y., Kishimoto, H., & Soga, K. (2013) · Nanoscale · doi:10.1039/c3nr02286b · Cited by 343 · see citing works

Metabolizable Semiconducting Polymer Nanoparticles for Second Near‐Infrared Photoacoustic Imaging

Jiang, Y., Upputuri, P. K., Xie, C., Zeng, Z., Sharma, A., Xu, Z. J., Li, J., Huang, J., Pramanik, M., & Pu, K. (2019) · Advanced Materials · doi:10.1002/adma.201808166 · Cited by 339 · see citing works

Advanced optoacoustic methods for multiscale imaging of in vivo dynamics

Deán‐Ben, X. L., Gottschalk, S., Larney, B. M., Shoham, S., & Razansky, D. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00765a · Cited by 338 · see citing works

Gold Nanozymes: From Concept to Biomedical Applications

Lou-Franco, J., Das, B., Elliott, C. T., & Cao, C. (2020) · Nano-Micro Letters · doi:10.1007/s40820-020-00532-z · Cited by 333 · see citing works

Sub‐10‐nm Pd Nanosheets with Renal Clearance for Efficient Near‐Infrared Photothermal Cancer Therapy

Tang, S., Chen, M., & Zheng, N. (2014) · Small · doi:10.1002/smll.201303631 · Cited by 327 · see citing works

Colloidal capsules: nano- and microcapsules with colloidal particle shells

Bollhorst, T., Rezwan, K., & Maas, M. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00632a · Cited by 324 · see citing works

CuS Nanodots with Ultrahigh Efficient Renal Clearance for Positron Emission Tomography Imaging and Image-Guided Photothermal Therapy

Zhou, M., Li, J., Su, L., Sood, A. K., Liang, D., & Li, C. (2015) · ACS Nano · doi:10.1021/acsnano.5b02635 · Cited by 324 · see citing works

Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles

Souris, J. S., Lee, C., Cheng, S., Chen, C.-T., Yang, C., Ho, J. A., Mou, C., & Lo, L. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.048 · Cited by 320 · see citing works

Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles

Tanaka, T., Mangala, L. S., Vivas‐Mejía, P. E., Nieves-Alicea, R., Mann, A. P., Mora, E., Han, H., Shahzad, M. M. K., Liu, X., Bhavane, R. C., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-3931 · Cited by 317 · see citing works

Clearance Pathways and Tumor Targeting of Imaging Nanoparticles for Diagnostics

Parikh, P. K., Parikh, N. H., Patel, J. K., & Pathak, Y. V. (2022) · Springer eBooks · doi:10.1007/978-3-030-83395-4_17 · Cited by 4 · see citing works

Renal clearance of quantum dots

Soo Choi, H., Liu, W., Misra, P., Tanaka, E., Zimmer, J. P., Itty Ipe, B., Bawendi, M. G., & Frangioni, J. V. (2007) · Nature Biotechnology · doi:10.1038/nbt1340 · Cited by 4,476 · see citing works

Renal clearable noble metal nanoparticles: photoluminescence, elimination, and biomedical applications

Xu, J., Peng, C., Yu, M., & Zheng, J. (2017) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1453 · Cited by 57 · see citing works

Renal clearable nanoparticles: An expanding horizon for improving biomedical imaging and cancer therapy

Mosleh-Shirazi, S., Abbasi, M., Shafiee, M., Kasaee, S. R., & Amani, A. M. (2021) · Materials Today Communications · doi:10.1016/j.mtcomm.2021.102064 · Cited by 63 · see citing works

Surface ligand-regulated renal clearance of MRI/SPECT dual-modality nanoprobes for tumor imagingPreprint

Chen, C., Huang, B., Zhang, R., Sun, C., Chen, L., Ge, J., Zhou, D., Li, Y., Wu, S., Qian, Z., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-3886645/v1