The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Upconversion Nanoprobes for the Ratiometric Luminescent Sensing of Nitric Oxide
Abstract
By taking advantage of the optical properties of upconversion nanoparticles (UCNPs), we have designed a luminescence ratiometric nanosensor for measuring nitric oxide (NO) in biological fluids, live cells, and tissues. This nanoconjugate consists of a UCNP core with two strong fluorescence emission peaks at 540 and 656 nm as the upconversion fluorophore, NO-reactive rhodamine B-derived molecules (RdMs) encapsulated within the mesopores of the mSiO 2 shell, and a β-cyclodextrin (βCD) layer on the exterior of the particle. Reaction of the analyte with the O -phenylenediamine of the RdM induces opening of the spiro-ring and is accompanied by an appearance of a strong rhodamine B (RdB) absorption band between 500 and 600 nm, which has spectral overlap with the green emission (540 nm) of the UCNPs. This results in an increase in the I 656 / I 540 ratio and quantitatively correlates with [NO]. The assay is validated under clean buffer conditions as well as inserum and liver tissue slices obtained from mouse models.
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Cites
Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species
Chen, X., Tian, X., Shin, I., & Yoon, J. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15037e · Cited by 980
Cited by
Ratiometric optical nanoprobes enable accurate molecular detection and imaging
Huang, X., Song, J., Yung, B. C., Huang, X., Xiong, Y., & Chen, X. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00612h · Cited by 820
Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells
Zhao, J., Gao, J., Xue, W., Di, Z., Xing, H., Lu, Y., & Li, L. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b11161 · Cited by 361
Gu, B., & Zhang, Q. (2018) · Advanced Science · doi:10.1002/advs.201700609 · Cited by 292
Wang, C., Lin, H., Ge, X., Mu, J., Su, L., Zhang, X., Niu, M., Yang, H., & Song, J. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202009942 · Cited by 89
Unlocking the NIR‐II AIEgen for High Brightness through Intramolecular Electrostatic Locking
Wang, X., Yang, X., Jiang, G., Hu, Z., Liao, T., Wang, G., Zhang, X., He, X., Zhang, J., Zhang, J., et al. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202404142 · Cited by 44
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Metadata
- Authors
- Wang, N., Yu, X., Zhang, K., Mirkin, C. A., & Li, J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-09-05
- Volume
- 139
- Issue
- 36
- Pages
- 12354-12357
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2746891585
- Cited by
- 165
- References
- 1
- FWCI
- 7.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wang, N., Yu, X., Zhang, K., Mirkin, C. A., & Li, J. (2017). Upconversion Nanoprobes for the Ratiometric Luminescent Sensing of Nitric Oxide. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.7b06059
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