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Identification and Biological Activities of Triterpenoid Saponins from Chenopodium quinoa

Woldemichael, Girma Moges, Wink, Michael·2001·Journal of Agricultural and Food Chemistry

Abstract

At least 16 saponins were detected in the seeds of Chenopodium quinoa. The 5 previously isolated major saponins, 3-O-beta-D-glucuronopyranosyl oleanolic acid 28-O-beta-D-glucopyranosyl ester, 3-O-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl ester, 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl ester, 3-O-alpha-L-arabinopyranosyl phytolaccagenic acid 28-O-beta-D-glucopyranosyl ester, 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl phytolaccagenic acid 28-O-beta-D-glucopyranosyl ester, and the new saponin 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl phytolaccagenic acid were isolated and characterized using mainly NMR spectroscopy, mass spectrometry, and chemical methods. The antifungal activity against Candida albicans and hemolytic activity on erythrocytes of these compounds and derived monodesmosides were evaluated. Both bidesmosides and derived monodesmosides showed little or no antifungal activity, whereas a comparatively higher degree of hemolytic activity could be determined for monodesmosides.

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Metadata

Authors
Woldemichael, G. M., & Wink, M.
Venue
Journal of Agricultural and Food Chemistry
Published
2001-04-17
Volume
49
Issue
5
Pages
2327-2332
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
OpenAlex
W2049642856
Cited by
219
References
0
FWCI
0.65
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Identification and Biological Activities of Triterpenoid Saponins from Chenopodium quinoa. https://app.cochat.ai/papers/10.1021/jf0013499
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Woldemichael, G. M., & Wink, M. (2001). Identification and Biological Activities of Triterpenoid Saponins from Chenopodium quinoa. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf0013499

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