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Cited by 225

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Quercetin, but not Its Glycosides, Is Absorbed from the Rat Stomach

Crespy, Vanessa, Morand, Christine, Besson, Catherine, Manach, Claudine, Demigne, Christian, Remesy, Christian·2002·Journal of Agricultural and Food Chemistry
DOI 10.1021/jf010919h
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Abstract

Absorption and metabolism of quercetin, isoquercitrin (quercetin 3-O-glucose), and rutin (quercetin 3-O-glucose-rhamnose) were investigated in rats after in situ gastric administration (15 micromol/L) for 30 min. At the end of the experiment, 38% of the initial dose of quercetin had disappeared. Quercetin was rapidly absorbed by the stomach, and was recovered in the bile 20 min after infusion (4.07 +/- 0.10 micromol/L). The administration of rutin and isoquercitrin indicated that these glycosides were not hydrolyzed nor absorbed by this tissue. In conclusion, when flavonols are present in the diet as aglycons, they could be partly absorbed in the stomach, in contrast to their glycosidic forms which are not absorbed.

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Metadata

Authors
Crespy, V., Morand, C., Besson, C., Manach, C., Demigne, C., & Remesy, C.
Venue
Journal of Agricultural and Food Chemistry
Publisher
American Chemical Society (ACS)
Published
2001-12-21
Volume
50
Issue
3
Pages
618-621
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
DOI
10.1021/jf010919h
OpenAlex
W2051841299
Cited by
225
References
0
FWCI
4.46
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Quercetin, but not Its Glycosides, Is Absorbed from the Rat Stomach. https://app.cochat.ai/papers/10.1021/jf010919h
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Crespy, V., Morand, C., Besson, C., Manach, C., Demigne, C., & Remesy, C. (2002). Quercetin, but not Its Glycosides, Is Absorbed from the Rat Stomach. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf010919h

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.