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Antioxidant Activity of Chemical Components from Sage (Salvia officinalis L.) and Thyme (Thymus vulgaris L.) Measured by the Oil Stability Index Method
Abstract
A new abietane diterpenoid, 12- O -methyl carnosol ( 2 ), was isolated from the leaves of sage ( Salvia officinalis L.), together with 11 abietane diterpenoids, 3 apianane terpenoids, 1 anthraquinone, and 8 flavonoids. Antioxidant activity of these compounds along with 4 flavonoids isolated from thyme ( Thymus vulgaris L.) was evaluated by the oil stability index method using a model substrate oil including methyl linoleate in silicone oil at 90 °C. Carnosol, rosmanol, epirosmanol, isorosmanol, galdosol, and carnosic acid exhibited remarkably strong activity, which was comparable to that of α-tocopherol. The activity of miltirone, atuntzensin A, luteolin, 7- O -methyl luteolin, and eupafolin was comparable to that of butylated hydroxytoluene. The activity of these compounds was mainly due to the presence of ortho -dihydroxy groups. The 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity of these compounds showed the similar result. Keywords: Salvia officinalis L.; sage; Thymus vulgaris L.; thyme; 12- O -methyl carnosol; apianane terpenoid; abietane diterpenoid; flavonoid; antioxidative activity; oil stability index; OSI; DPPH radical scavenging activity
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Citations
Cited by
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Lopez-Lazaro, M. (2009) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955709787001712 · Cited by 1,106
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Hu, Y., Xu, J., & Hu, Q. (2003) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf034255i · Cited by 309
The Effect of an Essential Oil Mix Derived from Oregano, Clove and Anise on Broiler Performance
., O. N. E., ., T. G., ., M. C., Dalkilic, B., & ., U. G. S. (2005) · International Journal of Poultry Science · doi:10.3923/ijps.2005.879.884 · Cited by 203
Effects of a Combination of Thyme and Oregano Essential Oils on TNBS-Induced Colitis in Mice
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Metadata
- Authors
- Miura, K., Kikuzaki, H., & Nakatani, N.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-02-16
- Volume
- 50
- Issue
- 7
- Pages
- 1845-1851
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2033129984
- Cited by
- 276
- References
- 0
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Miura, K., Kikuzaki, H., & Nakatani, N. (2002). Antioxidant Activity of Chemical Components from Sage (Salvia officinalis L.) and Thyme (Thymus vulgaris L.) Measured by the Oil Stability Index Method. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf011314o
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