Pharmacological properties of Salvia officinalis and its components
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Salvia officinalis (Sage) is a plant in the family of Labiatae/Lamiaceae. It is native to Middle East and Mediterranean areas, but today has been naturalized throughout the world. In folk medicine, S. officinalis has been used for the treatment of different kinds of disorders including seizure, ulcers, gout, rheumatism, inflammation, dizziness, tremor, paralysis, diarrhea, and hyperglycemia. In recent years, this plant has been a subject of intensive studies to document its traditional use and to find new biological effects. These studies have revealed a wide range of pharmacological activities for S. officinalis. Present review highlights the up-to-date information on the pharmacological findings that have been frequently reported for S. officinalis . These findings include anticancer, anti-inflammatory, antinociceptive, antioxidant, antimicrobial, antimutagenic, antidementia, hypoglycemic, and hypolipidemic effects. Also, chemical constituents responsible for pharmacological effects of S. officinalis and the clinical studies on this plant are presented and discussed.
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Salvia officinalis has AChE inhibitory activity.
“AChE inhibitory activity”
From Unlocking the Therapeutic Potential of Medicinal Plants for Alzheimer’s Disease: Preclinical to Clinical Trial Insights (2023) · cites this paper as [157]
Salvia officinalis affects the pathogenesis of dementia.
“pathogenesis of”
From Unlocking the Therapeutic Potential of Medicinal Plants for Alzheimer’s Disease: Preclinical to Clinical Trial Insights (2023) · cites this paper as [157]
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The Current State of Knowledge on Salvia hispanica and Salviae hispanicae semen (Chia Seeds)
Motyka, S., Koc, K., Ekiert, H., Blicharska, E., Czarnek, K., & Szopa, A. (2022) · Molecules · doi:10.3390/molecules27041207 · Cited by 58 · see citing works
Nagori, K., Nakhate, K. T., Yadav, K., Ajazuddin, & Pradhan, M. (2023) · Future Pharmacology · doi:10.3390/futurepharmacol3040053 · Cited by 61 · see citing works
Amini, L., Mojab, F., Jahanfar, S., Sepidarkish, M., Raoofi, Z., & Maleki-Hajiagha, A. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.102245 · Cited by 30 · see citing works
Dumitru, C. N., Mariana, L., Budacu, C. C., Mitea, G., Radu, M. D., Dumitru, A. O., Lupoae, A., Tatu, A., & Topor, G. (2025) · Dentistry Journal · doi:10.3390/dj13050222 · Cited by 17 · see citing works
Hernández-Rangel, A. E., Cabrera-Licona, A., Hernandez-Fuentes, G. A., Beas-Guzmán, O. F., Martínez-Martínez, F. J., Alcalá-Pérez, M. A., Montes-Galindo, D. A., Rodriguez-Sanchez, I. P., Martinez-Fierro, M. L., Casarez-Price, J. C., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12081804 · Cited by 7 · see citing works
- Authors
- Ghorbani, A., & Esmaeilizadeh, M.
- Affiliations
- Mashhad University of Medical Sciences (IR)
- Esfarayen University of Technology (IR)
- Corresponding author
- Esmaeilizadeh, Mahdi
- Venue
- Journal of Traditional and Complementary Medicine
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 7
- Issue
- 4
- Pages
- 433-440
- ISSN
- 2225-4110 (ISSN-L)
- PMC
- PMC5634728
- OpenAlex
- W2574328694
- Cited by
- 677
- References
- 104
- Citations by year
- 2026: 56 · 2025: 106 · 2024: 80 · 2023: 104 · 2022: 88 · 2021: 103 · 2020: 75 · 2019: 44 · 2018: 18 · 2017: 2 · 2014: 1
- FWCI
- 37.40
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Journal of Traditional and Complementary Medicine (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Mashhad University of Medical Sciences
- Esfarayen Faculty of Medical Sciences
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plant Extracts Effects
- Keywords
- Salvia officinalis, sage, pharmacological activity, anticancer activity, anti-inflammatory activity, antinociceptive activity, antioxidant activity, antimicrobial activity, antimutagenic activity, hypoglycemic activity, hypolipidemic activity, chemical constituents, traditional medicine, Lamiaceae
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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