Cited by 677Medicinal Plant ResearchPhytochemistry and Biological ActivitiesMedicinal Plant Extracts Effects

Pharmacological properties of Salvia officinalis and its components

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Ghorbani, Ahmad, Esmaeilizadeh, Mahdi·2017·Journal of Traditional and Complementary Medicine

Abstract

Salvia officinalis (Sage) is a plant in the family of Labiatae/Lamiaceae. It is native to Middle East and Mediterranean areas, but today has been naturalized throughout the world. In folk medicine, S. officinalis has been used for the treatment of different kinds of disorders including seizure, ulcers, gout, rheumatism, inflammation, dizziness, tremor, paralysis, diarrhea, and hyperglycemia. In recent years, this plant has been a subject of intensive studies to document its traditional use and to find new biological effects. These studies have revealed a wide range of pharmacological activities for S. officinalis. Present review highlights the up-to-date information on the pharmacological findings that have been frequently reported for S. officinalis . These findings include anticancer, anti-inflammatory, antinociceptive, antioxidant, antimicrobial, antimutagenic, antidementia, hypoglycemic, and hypolipidemic effects. Also, chemical constituents responsible for pharmacological effects of S. officinalis and the clinical studies on this plant are presented and discussed.

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  1. [1]Bisset N.G. Wichtl M. Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis with Reference to German Commision E Monographs 2nd ed. 2001 CRC Press Boca Raton, FI 440 443
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  3. [29]Sertel S. Eichhorn T. Plinkert P.K. Efferth T. Anticancer activity of Salvia officinalis essential oil against HNSCC cell line (UMSCC1) HNO 59 2011 1203 1208 21894557
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Authors
Ghorbani, A., & Esmaeilizadeh, M.
Affiliations
  • Mashhad University of Medical Sciences (IR)
  • Esfarayen University of Technology (IR)
Corresponding author
Esmaeilizadeh, Mahdi
Venue
Journal of Traditional and Complementary Medicine
Publisher
Elsevier BV
Published
2017-10
Volume
7
Issue
4
Pages
433-440
ISSN
2225-4110 (ISSN-L)
OpenAlex
W2574328694
Cited by
677
References
104
Citations by year
2026: 56 · 2025: 106 · 2024: 80 · 2023: 104 · 2022: 88 · 2021: 103 · 2020: 75 · 2019: 44 · 2018: 18 · 2017: 2 · 2014: 1
FWCI
37.40
Type
journal article
Language
en
Open access
Locations
  • Journal of Traditional and Complementary Medicine (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Mashhad University of Medical Sciences
  • Esfarayen Faculty of Medical Sciences
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plant Extracts Effects
Keywords
Salvia officinalis, sage, pharmacological activity, anticancer activity, anti-inflammatory activity, antinociceptive activity, antioxidant activity, antimicrobial activity, antimutagenic activity, hypoglycemic activity, hypolipidemic activity, chemical constituents, traditional medicine, Lamiaceae

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