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Plasma and Urine Responses Are Lower for Acylated vs Nonacylated Anthocyanins from Raw and Cooked Purple Carrots

Kurilich, Anne C., Clevidence, Beverly A., Britz, Steven J., Simon, Philipp W., Novotny, Janet A.·2005·Journal of Agricultural and Food Chemistry

Abstract

The bioavailability of acylated vs nonacylated anthocyanins and the effect of cooking and dose on the comparative bioavailability were investigated in a clinical feeding study using purple carrots as the anthocyanin source. Treatments were purple carrots as follows: 250 g raw (463 micromol of anthocyanins: 400 micromol acylated, 63 micromol nonacylated), 250 g cooked (357 micromol of anthocyanins: 308.5 micromol acylated, 48.5 micromol nonacylated), and 500 g cooked (714 micromol of anthocyanins: 617 micromol acylated, 97 micromol nonacylated). Four of the five carrot anthocyanins were found intact in plasma by 30 min after carrot consumption and peaked between 1.5 and 2.5 h. Acylation of anthocyanins resulted in an 11-14-fold decrease in anthocyanin recovery in urine and an 8-10-fold decrease in anthocyanin recovery in plasma. Cooking increased the recovery of nonacylated anthocyanins but not acylated anthocyanins. Large dose size significantly reduced recovery of both acylated and nonacylated anthocyanins, suggesting saturation of absorption mechanisms.

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Metadata

Authors
Kurilich, A. C., Clevidence, B. A., Britz, S. J., Simon, P. W., & Novotny, J. A.
Venue
Journal of Agricultural and Food Chemistry
Published
2005-07-07
Volume
53
Issue
16
Pages
6537-6542
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
OpenAlex
W1972768097
Cited by
173
References
2
FWCI
2.97
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Plasma and Urine Responses Are Lower for Acylated vs Nonacylated Anthocyanins from Raw and Cooked Purple Carrots. https://app.cochat.ai/papers/10.1021/jf050570o
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Kurilich, A. C., Clevidence, B. A., Britz, S. J., Simon, P. W., & Novotny, J. A. (2005). Plasma and Urine Responses Are Lower for Acylated vs Nonacylated Anthocyanins from Raw and Cooked Purple Carrots. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf050570o

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