The DOI matches its Crossref record.
Antibacterial and Antioxidant Activities of Quercetin Oxidation Products from Yellow Onion (Allium cepa) Skin
Abstract
Four new quercetin-derived oxidation products (1-4) and lunularin-4-O-beta-D-glucoside (5) were isolated from a water extract of onion (Allium cepa) skin, together with 17 other known compounds. Antibacterial assays for the isolated compounds showed that 2-(3,4-dihydroxyphenyl)-4,6-dihydroxy-2-methoxybenzofuran-3-one (1) presented selective activity against Helicobacter pylori strains and 3-(quercetin-8-yl)-2,3-epoxyflavanone (4) showed antibacterial activity against MRSA and H. pylori strains at the same time that it increased susceptibility of MRSA to beta-lactams. Evaluation of antioxidant activity against DPPH for the isolated compounds showed that the new derivative compounds (1-4) and 2,5,7,3',4'-pentahydroxy-3,4-flavandione (6) are more active than quercetin.
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Citations
Cited by
Overviews of biological importance of quercetin: A bioactive flavonoid
Parasuraman, S., Anand David, A., & Arulmoli, R. (2016) · Pharmacognosy Reviews · doi:10.4103/0973-7847.194044 · Cited by 1,610
Biological properties of onions and garlic
CORZOMARTINEZ, M., CORZO, N., & VILLAMIEL, M. (2007) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2007.07.011 · Cited by 810
Effect of thermal processing on the flavonols rutin and quercetin
Buchner, N., Krumbein, A., Rohn, S., & Kroh, L. W. (2006) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.2720 · Cited by 450
Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells
Vafadar, A., Shabaninejad, Z., Movahedpour, A., Fallahi, F., Taghavipour, M., Ghasemi, Y., Akbari, M., Shafiee, A., Hajighadimi, S., Moradizarmehri, S., et al. (2020) · Cell & Bioscience · doi:10.1186/s13578-020-00397-0 · Cited by 296
Najafabadi, R. E., Kazemipour, N., Esmaeili, A., Beheshti, S., & Nazifi, S. (2018) · Advanced Biomedical Research · doi:10.4103/abr.abr_141_17 · Cited by 18
Metadata
- Authors
- Ramos, F. A., Takaishi, Y., Shirotori, M., Kawaguchi, Y., Tsuchiya, K., Shibata, H., Higuti, T., Tadokoro, T., & Takeuchi, M.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-04-21
- Volume
- 54
- Issue
- 10
- Pages
- 3551-3557
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W1992967507
- Cited by
- 252
- References
- 0
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ramos, F. A., Takaishi, Y., Shirotori, M., Kawaguchi, Y., Tsuchiya, K., Shibata, H., Higuti, T., Tadokoro, T., & Takeuchi, M. (2006). Antibacterial and Antioxidant Activities of Quercetin Oxidation Products from Yellow Onion (Allium cepa) Skin. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf060251c
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