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Cited by 178

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Solid Lipid Nanoparticles Co-loaded with Simazine and Atrazine: Preparation, Characterization, and Evaluation of Herbicidal Activity

de Oliveira, Jhones Luiz, Campos, Estefânia Vangelie Ramos, Gonçalves da Silva, Camila Morais, Pasquoto, Tatiane, Lima, Renata, Fraceto, Leonardo Fernandes·2015·Journal of Agricultural and Food Chemistry

Abstract

Solid lipid nanoparticles (SLN) containing the herbicides atrazine and simazine were prepared and characterized, and in vitro evaluation was made of the release kinetics, herbicidal activity, and cytotoxicity. The stability of the nanoparticles was investigated over a period of 120 days, via analyses of particle size, ζ potential, polydispersion, pH, and encapsulation efficiency. SLN showed good physicochemical stability and high encapsulation efficiencies. Release kinetics tests showed that use of SLN modified the release profiles of the herbicides in water. Herbicidal activity assays performed with pre- and postemergence treatment of the target species Raphanus raphanistrum showed the effectiveness of the formulations of nanoparticles containing herbicides. Assays with nontarget organisms (Zea mays) showed that the formulations did not affect plant growth. The results of cytotoxicity assays indicated that the presence of SLN acted to reduce the toxicity of the herbicides. The new nanoparticle formulations enable the use of smaller quantities of herbicide and therefore offer a more environmentally friendly method of controlling weeds in agriculture.

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Metadata

Authors
de Oliveira, J. L., Campos, E. V. R., Gonçalves da Silva, C. M., Pasquoto, T., Lima, R., & Fraceto, L. F.
Venue
Journal of Agricultural and Food Chemistry
Published
2015-01-09
Volume
63
Issue
2
Pages
422-432
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
OpenAlex
W2043869453
Cited by
178
References
1
FWCI
3.48
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Solid Lipid Nanoparticles Co-loaded with Simazine and Atrazine: Preparation, Characterization, and Evaluation of Herbicidal Activity. https://app.cochat.ai/papers/10.1021/jf5059045
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de Oliveira, J. L., Campos, E. V. R., Gonçalves da Silva, C. M., Pasquoto, T., Lima, R., & Fraceto, L. F. (2015). Solid Lipid Nanoparticles Co-loaded with Simazine and Atrazine: Preparation, Characterization, and Evaluation of Herbicidal Activity. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf5059045

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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