Biodegradable polymeric nanoparticles as drug delivery devices
Abstract
This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems. Methods of preparation, drug loading and drug release are covered. The most important findings on surface modification methods as well as surface characterization are covered from 1990 through mid-2000.
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A substantial number of preclinical and clinical studies suggest suitability of nanoparticles, liposomes, micelles, and dendrimers for treatment of various diseases.
“A substantial number of preclinical and clinical studies suggest their suitability for the treatment of various diseases.20–22”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [22]
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- Authors
- Soppimath, K. S., Aminabhavi, T. M., Kulkarni, A. R., & Rudzinski, W. E.
- Affiliations
- Karnatak University (IN)
- Texas State University (US)
- Corresponding author
- Aminabhavi, Tejraj M
- Venue
- Journal of Controlled Release
- Publisher
- Elsevier BV
- Published
- 2001-01
- Volume
- 70
- Issue
- 1-2
- Pages
- 1-20
- ISSN
- 0168-3659 (ISSN-L)
- OpenAlex
- W1996998905
- Cited by
- 3,549
- References
- 140
- Citations by year
- 2026: 80 · 2025: 88 · 2024: 112 · 2023: 133 · 2022: 143 · 2021: 150 · 2020: 196 · 2019: 201 · 2018: 211 · 2017: 229 · 2016: 247 · 2015: 229 · 2014: 245 · 2013: 191 · 2012: 218
- FWCI
- 2.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Controlled Release (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Physical Sciences › Materials Science › Polymers and Plastics › Dendrimers and Hyperbranched Polymers
- Keywords
- biodegradable polymer nanoparticles, drug delivery systems, nanoparticle synthesis, drug loading, controlled drug release, surface modification, surface characterization
- MeSH terms
- Adsorption, Biodegradation, Environmental, Emulsions, Phagocytosis, Proteins, Surface Properties, Drug Delivery Systems
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