Cited by 3,549Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsDendrimers and Hyperbranched Polymers

Biodegradable polymeric nanoparticles as drug delivery devices

Soppimath, Kumaresh S, Aminabhavi, Tejraj M, Kulkarni, Anandrao R, Rudzinski, Walter E·2001·Journal of Controlled Release

Abstract

This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems. Methods of preparation, drug loading and drug release are covered. The most important findings on surface modification methods as well as surface characterization are covered from 1990 through mid-2000.

Integrity signals

Registry

Crossref · 10.1016/s0168-3659(00)00339-4

Cites

140 of 140 references verified0 citation errors · 0 not checkable

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  • A substantial number of preclinical and clinical studies suggest suitability of nanoparticles, liposomes, micelles, and dendrimers for treatment of various diseases.

    “A substantial number of preclinical and clinical studies suggest their suitability for the treatment of various diseases.20–22”

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Authors
Soppimath, K. S., Aminabhavi, T. M., Kulkarni, A. R., & Rudzinski, W. E.
Affiliations
  • Karnatak University (IN)
  • Texas State University (US)
Corresponding author
Aminabhavi, Tejraj M
Venue
Journal of Controlled Release
Publisher
Elsevier BV
Published
2001-01
Volume
70
Issue
1-2
Pages
1-20
ISSN
0168-3659 (ISSN-L)
OpenAlex
W1996998905
Cited by
3,549
References
140
Citations by year
2026: 80 · 2025: 88 · 2024: 112 · 2023: 133 · 2022: 143 · 2021: 150 · 2020: 196 · 2019: 201 · 2018: 211 · 2017: 229 · 2016: 247 · 2015: 229 · 2014: 245 · 2013: 191 · 2012: 218
FWCI
2.96
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Controlled Release (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
  • Physical Sciences › Materials Science › Polymers and Plastics › Dendrimers and Hyperbranched Polymers
Keywords
biodegradable polymer nanoparticles, drug delivery systems, nanoparticle synthesis, drug loading, controlled drug release, surface modification, surface characterization
MeSH terms
Adsorption, Biodegradation, Environmental, Emulsions, Phagocytosis, Proteins, Surface Properties, Drug Delivery Systems

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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