The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Inhibition of Human Low-Density Lipoprotein Oxidation in Relation to Composition of Phenolic Antioxidants in Grapes (Vitis vinifera)
Abstract
Antioxidant activities of phenolic extracts from fourteen different types of fresh grapes were investigated by measuring the inhibition of human low-density lipoprotein (LDL) oxidation in vitro . The inhibition of LDL oxidation ranged from 22% to 60% at 10 μM gallic acid equivalents (GAE) of total phenols and from 62% to 91% at 20 μM GAE. The antioxidant activities were thus comparable to those previously found for wines. The relative LDL antioxidant activity correlated with the concentration of total phenols ( r = 0.89, p < 0.01), with the level of anthocyanins ( r = 0.56, p < 0.05) and flavonols ( r = 0.54, p < 0.05) in the grape extracts as analyzed by high-performance liquid chromatography (HPLC). When seed crushing and longer extraction times were employed, high amounts of flavan-3-ols and hydroxybenzoates were extracted. With these extracts relative LDL antioxidant activity correlated highly with the levels of flavan-3-ols ( r = 0.86, p < 0.01), total phenols ( r = 0.79, p < 0.05), and hydroxybenzoates ( r = 0.77, p < 0.05). Keywords: LDL oxidation; flavonoids; hydroxycinnamates; anthocyanins; flavan-3-ols; flavonols; HPLC
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Citations
Cites
Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents
Singleton, V. L., & Rossi, J. A. (1965) · American Journal of Enology and Viticulture · doi:10.5344/ajev.1965.16.3.144 · Cited by 24,852
Cited by
The Chemistry behind Antioxidant Capacity Assays
Huang, D., Ou, B., & Prior, R. L. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf030723c · Cited by 6,162
Antioxidant activity of plant extracts containing phenolic compounds
Kähkönen, M. P., Hopia, A. I., Vuorela, H. J., Rauha, J.-P., Pihlaja, K., Kujala, T. S., & Heinonen, M. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990146l · Cited by 3,854
Frankel, E. N., & Meyer, A. S. (2000) · Journal of the Science of Food and Agriculture · doi:10.1002/1097-0010(200010)80:13<1925::aid-jsfa714>3.0.co;2-4 · Cited by 1,120
Self-citationBiological Activities of Polyphenols from Grapes
Xia, E.-Q., Deng, G.-F., Guo, Y.-J., & Li, H.-B. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11020622 · Cited by 1,063
Antibacterial and antioxidant activities of grape (Vitis vinifera) seed extracts
Jayaprakasha, G. K., Selvi, T., & Sakariah, K. K. (2003) · Food Research International · doi:10.1016/s0963-9969(02)00116-3 · Cited by 660
Metadata
- Authors
- Meyer, A. S., Yi, O.-S., Pearson, D. A., Waterhouse, A. L., & Frankel, E. N.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1997-05-01
- Volume
- 45
- Issue
- 5
- Pages
- 1638-1643
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2079798291
- Cited by
- 325
- References
- 1
- FWCI
- 8.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Meyer, A. S., Yi, O.-S., Pearson, D. A., Waterhouse, A. L., & Frankel, E. N. (1997). Inhibition of Human Low-Density Lipoprotein Oxidation in Relation to Composition of Phenolic Antioxidants in Grapes (Vitis vinifera). Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf960721a
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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