The DOI matches its Crossref record.
Determination of Bisphenol-A in Reusable Polycarbonate Food-Contact Plastics and Migration to Food-Simulating Liquids
Abstract
Bisphenol-A (BPA) is a principal reactant in the preparation of polycarbonate (PC) plastics and has been shown in in vitro cell proliferation studies to exhibit estrogen-like characteristics. Reusable baby bottles, water carboys, and other housewares are often made of PC. A high-pressure liquid chromatographic (HPLC) protocol was used to determine residual BPA in PC and BPA migrated to food simulants in contact with PC under controlled time/temperature conditions. Confirmation of BPA was performed by gas chromatography/mass spectrometry (GC−MS). Residual amounts of BPA found in PC food contact articles ranged from 7 to 58 μg/g. In migration tests the plastic was exposed to water, ethanol/water mixtures, and Miglyol (a food oil simulant) in sealed vials at a constant temperature of 65 °C, for up to 10 days. BPA in food simulants ranged from 13 to 368% of BPA available to migrate from the polymer. GC−MS methods were applied to the analysis of water stored in reusable PC 5-gal water carboys. The amount of BPA found in the water ranged from ND to 5 ppb. Keywords: Bisphenol-A; polycarbonate; migration; baby bottles; hydrolysis
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Citations
Cited by
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Rubin, B. S., Lenkowski, J. R., Schaeberle, C. M., Vandenberg, L. N., Ronsheim, P. M., & Soto, A. M. (2006) · Endocrinology · doi:10.1210/en.2006-0189 · Cited by 311
Bisphenol A (BPA) in U.S. Food
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Metadata
- Authors
- Biles, J. E., McNeal, T. P., Begley, T. H., & Hollifield, H. C.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1997-09-01
- Volume
- 45
- Issue
- 9
- Pages
- 3541-3544
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2027093075
- Cited by
- 302
- References
- 0
- FWCI
- 3.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Biles, J. E., McNeal, T. P., Begley, T. H., & Hollifield, H. C. (1997). Determination of Bisphenol-A in Reusable Polycarbonate Food-Contact Plastics and Migration to Food-Simulating Liquids. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf970072i
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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