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Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?
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ADVERTISEMENT RETURN TO ISSUEPREVPerspectiveNEXTNatural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?David J. Newman†View Author Information Natural Products Branch, Developmental Therapeutics Program, DCTD, National Cancer Institute—Frederick, P.O. Box B, Frederick, Maryland 21702† Contact information. Telephone: +301.846.5387 . Facsimile: +301.846.6178. E-mail: [email protected]. The views expressed in this review are those of the author and are not necessarily the position of the U.S. Government.Cite this: J. Med. Chem. 2008, 51, 9, 2589–2599Publication Date (Web):April 5, 2008Publication History Received5 April 2007Published online5 April 2008Published inissue 1 May 2008https://pubs.acs.org/doi/10.1021/jm0704090https://doi.org/10.1021/jm0704090review-articleACS PublicationsCopyright © This article not subject to U.S. Copyright. Published 2008 by the American Chemical SocietyRequest reuse permissionsArticle Views10802Altmetric-Citations524LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Chemical structure,Inhibitors,Peptides and proteins,Pharmaceuticals,Receptors Get e-Alerts
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Citations
Cites
Natural products as sources of new drugs over the last 25 years
Newman, D. J., & Cragg, G. M. (2007) · Journal of Natural Products · doi:10.1021/np068054v · Cited by 5,517
Self-citation
Cited by
Natural products as sources of new drugs over the 30 years from 1981 to 2010
Newman, D. J., & Cragg, G. M. (2012) · Journal of Natural Products · doi:10.1021/np200906s · Cited by 4,687
Self-citationPredicting new molecular targets for known drugs
Keiser, M. J., Setola, V., Irwin, J. J., Laggner, C., Abbas, A. I., Hufeisen, S. J., Jensen, N. H., Kuijer, M. B., Matos, R. C., Tran, T. B., et al. (2009) · Nature · doi:10.1038/nature08506 · Cited by 1,667
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
Doak, B. C., Over, B., Giordanetto, F., & Kihlberg, J. (2014) · Chemistry & Biology · doi:10.1016/j.chembiol.2014.08.013 · Cited by 835
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Metadata
- Authors
- Newman, D. J.
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-04-05
- Volume
- 51
- Issue
- 9
- Pages
- 2589-2599
- ISSN
- 0022-2623 (ISSN-L)
- 1520-4804
- OpenAlex
- W2084366893
- Cited by
- 716
- References
- 1
- FWCI
- 28.56
- Type
- journal article
- Language
- en
- Open access
- green
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