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Cited by 171

The DOI matches its Crossref record.

Gold Nanoparticle Based FRET Asssay for the Detection of DNA Cleavage

Ray, Paresh Chandra, Fortner, Angela, Darbha, Gopala Krishna·2006·The Journal of Physical Chemistry B
DOI 10.1021/jp065121l
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Abstract

We report gold nanoparticle based FRET assay to monitor the cleavage of DNA by nucleases. Fluorescence signal enhancement is observed by a factor of 120 after the cleavage reaction in the presence of S1 nuclease. The mechanism of distant dependent fluorescence quenching has been discussed. Our experimental results on distance dependent fluorescence quenching match quite well with theoretical findings obtained from the fluorescence quenching model by Gersten and Nitzan (Surf. Sci. 1985, 158, 165). Our experimental observation paradigm for the design of optical based molecular ruler strategies at distances more than double the distances achievable using traditional dipole-dipole Columbic energy transfer based methods.

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Metadata

Authors
Ray, P. C., Fortner, A., & Darbha, G. K.
Venue
The Journal of Physical Chemistry B
Publisher
American Chemical Society (ACS)
Published
2006-10-01
Volume
110
Issue
42
Pages
20745-20748
ISSN
  • 1520-5207 (ISSN-L)
  • 1520-6106
DOI
10.1021/jp065121l
OpenAlex
W2044076113
Cited by
171
References
0
FWCI
6.56
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Gold Nanoparticle Based FRET Asssay for the Detection of DNA Cleavage. https://app.cochat.ai/papers/10.1021/jp065121l
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Ray, P. C., Fortner, A., & Darbha, G. K. (2006). Gold Nanoparticle Based FRET Asssay for the Detection of DNA Cleavage. The Journal of Physical Chemistry B. https://doi.org/10.1021/jp065121l

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.