The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Polymeric Thin Films That Resist the Adsorption of Proteins and the Adhesion of Bacteria
Abstract
This paper describes the design and preparation of thin polymeric films that resist the adsorption of proteins and the adhesion of bacteria to an extent comparable to, or better than, self-assembled monolayers (SAMs) that present tri(ethylene glycol) groups. These polymeric films were prepared by the reaction of a polyamine, for example, poly(ethylenimine), with a SAM that presented interchain carboxylic anhydride groups, and by the subsequent conversion of the amino groups of the polymer to amido groups on reaction with acyl chlorides. Polyamines functionalized with acetyl chloride produced films that resisted the adsorption of protein and the adhesion of bacteria to a useful extent. Functionalization of the polyamine with acyl chlorides that were derivatives of oligo(ethylene glycol) resulted in films that were 1−10 times more resistant than those obtained by acetylation. The removal of hydrogen bond donor groups from the surface of the polyamines upon acylation seems to be important for the generation of films that resist the attachment of proteins and bacteria.
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Self-Assembled Organic Monolayers: Model Systems for Studying Adsorption of Proteins at Aurfaces
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Self-citationArginine-Mediated RNA Recognition: the Arginine Fork
Calnan, B. J., Tidor, B., Biancalana, S., Hudson, D., & Frankel, A. D. (1991) · Science · doi:10.1126/science.252.5009.1167 · Cited by 744
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Surveying for Surfaces that Resist the Adsorption of Proteins
Chapman, R. G., Ostuni, E., Takayama, S., Holmlin, R. E., Yan, L., & Whitesides, G. M. (2000) · Journal of the American Chemical Society · doi:10.1021/ja000774f · Cited by 600
Self-citationPolyurethanes in Biomedical Applications
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Electrochemical Glucose Biosensors
Wang, J. (2008) · Chemical Reviews · doi:10.1021/cr068123a · Cited by 3,498
Soft Lithography in Biology and Biochemistry
Whitesides, G. M., Ostuni, E., Takayama, S., Jiang, X., & Ingber, D. E. (2001) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.3.1.335 · Cited by 2,607
Self-citationA Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein
Ostuni, E., Chapman, R. G., Holmlin, R. E., Takayama, S., & Whitesides, G. M. (2001) · Langmuir · doi:10.1021/la010384m · Cited by 1,799
Self-citationSurface Modification of Water Purification Membranes
Miller, D. J., Dreyer, D. R., Bielawski, C. W., Paul, D. R., & Freeman, B. D. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201601509 · Cited by 747
Protein adsorption in three dimensions
Vogler, E. A. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.10.059 · Cited by 585
Metadata
- Authors
- Chapman, R. G., Ostuni, E., Liang, M. N., Meluleni, G., Kim, E., Yan, L., Pier, G., Warren, H. S., & Whitesides, G. M.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2001-01-26
- Volume
- 17
- Issue
- 4
- Pages
- 1225-1233
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W1977054660
- Cited by
- 356
- References
- 28
- FWCI
- 12.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chapman, R. G., Ostuni, E., Liang, M. N., Meluleni, G., Kim, E., Yan, L., Pier, G., Warren, H. S., & Whitesides, G. M. (2001). Polymeric Thin Films That Resist the Adsorption of Proteins and the Adhesion of Bacteria. Langmuir. https://doi.org/10.1021/la001222d
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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