The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Enhancement of Protein Adsorption Induced by Surface Roughness
Abstract
Using quartz crystal microbalance with dissipation and ellipsometry, we show that during adsorption of fibrinogen on evaporated tantalum films the saturation uptake increases with increasing root-mean-square roughness (from 2.0 to 32.9 nm) beyond the accompanying increase in surface area. This increase is attributed to a change in the geometrical arrangement of the fibrinogen molecules on the surface. For comparison, the adsorption of a nearly globular protein, bovine serum albumin, was studied as well. In this case, the adsorption was less influenced by the roughness. Simple Monte Carlo simulations taking into account surface roughness and the anisotropic shape of fibrinogen reproduce the experimentally observed trend.
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Citations
Cites
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The Density and Refractive Index of Adsorbing Protein Layers
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Barnacle cement protein as an efficient bioinspired corrosion inhibitor
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Metadata
- Authors
- Rechendorff, K., Hovgaard, M. B., Foss, M., Zhdanov, V. P., & Besenbacher, F.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-11-15
- Volume
- 22
- Issue
- 26
- Pages
- 10885-10888
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2036374139
- Cited by
- 591
- References
- 18
- FWCI
- 9.36
- Type
- journal article
- Language
- en
- Open access
- closed
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