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Hollow Silica Nanocontainers as Drug Delivery Vehicles
Open accessAbstract
Novel hollow silica nanoparticles (HSNPs) for drug delivery vehicles were synthesized using silica-coated magnetic assemblies, which are composed of a number of Fe(3)O(4) nanocrystals, as templates. The core cavity was obtained by removal of Fe(3)O(4) phase with hydrochloric acid and subsequent calcination at a high temperature. HSNPs were modified by amine in order to introduce positive surface charge and further PEGylated for increased solubility in aqueous medium. Doxorubicin as a model drug was loaded into the HSNPs, and notable sustained drug release from HSNPs was demonstrated.
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Cited by
Multi-shelled hollow micro-/nanostructures
Qi, J., Lai, X., Wang, J., Tang, H., Ren, H., Yang, Y., Jin, Q., Zhang, L., Yu, R., Ma, G., et al. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00344j · Cited by 676
Sol-Gel processing of silica nanoparticles and their applications
Singh, L. P., Bhattacharyya, S. K., Kumar, R., Mishra, G., Sharma, U., Singh, G., & Ahalawat, S. (2014) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2014.10.007 · Cited by 428
Monodisperse mesoporous superparamagnetic single-crystal magnetite nanoparticles for drug delivery
Guo, S., Li, D., Zhang, L., Li, J., & Wang, E. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2008.12.042 · Cited by 398
Lin, Y.-S., & Haynes, C. L. (2009) · Chemistry of Materials · doi:10.1021/cm901259n · Cited by 364
Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye
Guo, H., Qian, H., Sun, S., Sun, D., Yin, H., Cai, X., Liu, Z., Wu, J., Jiang, T., & Liu, X. (2011) · Chemistry Central Journal · doi:10.1186/1752-153x-5-1 · Cited by 299
Metadata
- Authors
- Yang, J., Lee, J., Kang, J., Lee, K., Suh, J.-S., Yoon, H.-G., Huh, Y.-M., & Haam, S.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-03-07
- Volume
- 24
- Issue
- 7
- Pages
- 3417-3421
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2007006701
- Cited by
- 240
- References
- 0
- FWCI
- 10.50
- Type
- journal article
- Language
- en
- Open access
- green
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- Yang, J., Lee, J., Kang, J., Lee, K., Suh, J.-S., Yoon, H.-G., Huh, Y.-M., & Haam, S. (2008). Hollow Silica Nanocontainers as Drug Delivery Vehicles. Langmuir. https://doi.org/10.1021/la701688t
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
