The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Film Thickness Dependence of Protein Adsorption from Blood Serum and Plasma onto Poly(sulfobetaine)-Grafted Surfaces
Abstract
In this work, we investigate protein adsorption from single protein solutions and complex media such as 100% blood serum and plasma onto poly(sulfobetaine methacrylate) (polySBMA)-grafted surfaces via atom transfer radical polymerization (ATRP) at varying film thicknesses. It is interesting to observe that protein adsorption exhibits a minimum at a medium film thickness. Results show that the surface with 62 nm polySBMA brushes presents the best nonfouling character in 100% blood serum and plasma although all of these surfaces are highly resistant to nonspecific protein adsorption from single fibrinogen and lysozyme solutions. Surface resistance to 100% blood serum or plasma is necessary for many applications from blood-contacting devices to drug delivery. This work provides a new in vitro evaluation standard for the application of biomaterials in vivo.
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Cites
A Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein
Ostuni, E., Chapman, R. G., Holmlin, R. E., Takayama, S., & Whitesides, G. M. (2001) · Langmuir · doi:10.1021/la010384m · Cited by 1,799
Biomaterials: Where We Have Been and Where We Are Going
Ratner, B. D., & Bryant, S. J. (2004) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.6.040803.140027 · Cited by 1,507
Cited by
A Switchable Biocompatible Polymer Surface with Self‐Sterilizing and Nonfouling Capabilities
Cheng, G., Xue, H., Zhang, Z., Chen, S., & Jiang, S. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200803570 · Cited by 371
Self-citationZhao, C., Li, L., & Zheng, J. (2010) · Langmuir · doi:10.1021/la103382j · Cited by 100
Engineering biomaterials surfaces to modulate the host response
Yu, K., Mei, Y., Hadjesfandiari, N., & Kizhakkedathu, J. N. (2014) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2014.08.009 · Cited by 58
Antifouling zwitterionic pSBMA‐MSN particles for biomedical applications
Beltrán‐Osuna, Á. A., Ródenas‐Rochina, J., Gómez Ribelles, J. L., & Perilla, J. E. (2019) · Polymers for Advanced Technologies · doi:10.1002/pat.4505 · Cited by 14
Metadata
- Authors
- Yang, W., Chen, S., Cheng, G., Vaisocherová, H., Xue, H., Li, W., Zhang, J., & Jiang, S.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-08-02
- Volume
- 24
- Issue
- 17
- Pages
- 9211-9214
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2012806326
- Cited by
- 258
- References
- 2
- FWCI
- 7.83
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yang, W., Chen, S., Cheng, G., Vaisocherová, H., Xue, H., Li, W., Zhang, J., & Jiang, S. (2008). Film Thickness Dependence of Protein Adsorption from Blood Serum and Plasma onto Poly(sulfobetaine)-Grafted Surfaces. Langmuir. https://doi.org/10.1021/la801487f
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