The DOI matches its Crossref record; 107 of the 107 references it cites were found in a registry or an index.
Polymer Scaffolds for Biomaterials Applications
Abstract
Biomaterials have been used extensively in medical, personal care, and food applications, with many similar polymers being used across disciplines. This Perspective will emphasize polymers used in medicine and specifically those designed as scaffolds for use in tissue engineering and regenerative medicine. The areas of active research in tissue engineering include: biomaterials design—incorporation of the appropriate chemical, physical, and mechanical/structural properties to guide cell and tissue organization; cell/scaffold integration—inclusion into the biomaterial scaffold of either cells for transplantation or biomolecules to attract cells, including stem cells, from the host to promote integration with the tissue after implantation; and biomolecule delivery—inclusion of growth factors and/or small molecules or peptides that promote cell survival and tissue regeneration. While a significant and growing area of regenerative medicine involves the stimulation of endogenous stem cells, this Perspective will emphasize polymer scaffolds used for delivery of cells and biomolecules. The challenges and solutions pursued in designing polymeric biomaterial scaffolds with the appropriate 3-dimensional structure will be explored.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
RETRACTED: Clinical transplantation of a tissue-engineered airway
Macchiarini, P., Jungebluth, P., Go, T., Asnaghi, M. A., Rees, L. E., Cogan, T. A., Dodson, A., Martorell, J., Bellini, S., Parnigotto, P. P., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61598-6 · Cited by 1,433
RetractedMatrix elasticity directs stem cell lineage specification
Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915
New Perspectives in Cell Adhesion: RGD and Integrins
Ruoslahti, E., & Pierschbacher, M. D. (1987) · Science · doi:10.1126/science.2821619 · Cited by 4,865
Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment
McBeath, R., Pirone, D. M., Nelson, C. M., Bhadriraju, K., & Chen, C. S. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00075-9 · Cited by 4,180
On the mechanisms of biocompatibility
Williams, D. F. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.023 · Cited by 2,772
Capturing complex 3D tissue physiology in vitro
Griffith, L. G., & Swartz, M. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1858 · Cited by 2,290
Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix
Guilak, F., Cohen, D. M., Estes, B. T., Gimble, J. M., Liedtke, W., & Chen, C. S. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2009.06.016 · Cited by 1,850
Polymeric system for dual growth factor delivery
Richardson, T. P., Peters, M. C., Ennett, A. B., & Mooney, D. J. (2001) · Nature Biotechnology · doi:10.1038/nbt1101-1029 · Cited by 1,752
Chitosan and its derivatives for tissue engineering applications
Kim, I.-Y., Seo, S.-J., Moon, H.-S., Yoo, M.-K., Park, I.-Y., Kim, B.-C., & Cho, C.-S. (2008) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.07.009 · Cited by 1,433
Novel injectable neutral solutions of chitosan form biodegradable gels in situ
Chenite, A., Chaput, C., Wang, D., Combes, C., Buschmann, M. D., Hoemann, C. D., Leroux, J. C., Atkinson, B. L., Binette, F., & Selmani, A. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00116-2 · Cited by 1,406
Cited by
Cellulose-based hydrogels: Present status and application prospects
Chang, C., & Zhang, L. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.12.023 · Cited by 1,081
Conducting Polymers for Tissue Engineering
Guo, B., & Ma, P. X. (2018) · Biomacromolecules · doi:10.1021/acs.biomac.8b00276 · Cited by 835
Substrates for cardiovascular tissue engineering
Bouten, C. V. C., Dankers, P. Y. W., Driessen-Mol, A., Pedron, S., Brizard, A. M. A., & Baaijens, F. P. T. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.01.007 · Cited by 261
Various manufacturing methods and ideal properties of scaffolds for tissue engineering applications
Suamte, L., Tirkey, A., Barman, J., & Jayasekhar Babu, P. (2023) · Smart Materials in Manufacturing · doi:10.1016/j.smmf.2022.100011 · Cited by 259
The Foreign Body Response Demystified
Chandorkar, Y., K, R., & Basu, B. (2019) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.8b00252 · Cited by 201
Metadata
- Authors
- Shoichet, M. S.
- Venue
- Macromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-12-15
- Volume
- 43
- Issue
- 2
- Pages
- 581-591
- ISSN
- 0024-9297 (ISSN-L)
- 1520-5835
- OpenAlex
- W2014785305
- Cited by
- 468
- References
- 107
- FWCI
- 16.80
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Polymer Scaffolds for Biomaterials Applications. https://app.cochat.ai/papers/10.1021/ma901530r
- The paper
- Shoichet, M. S. (2010). Polymer Scaffolds for Biomaterials Applications. Macromolecules. https://doi.org/10.1021/ma901530r
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.