The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Electronic Detection of Specific Protein Binding Using Nanotube FET Devices
Abstract
We have used nanoscale field effect transistor devices with carbon nanotubes as the conducting channel to detect protein binding. A PEI/PEG polymer coating layer has been employed to avoid nonspecific binding, with attachment of biotin to the layer for specific molecular recognition. Biotin-streptavidin binding has been detected by changes in the device characteristic. Nonspecific binding was observed in devices without the polymer coating, while no binding was found for polymer-coated but not biotinylated devices. Streptavidin, in which the biotin-binding sites were blocked by reaction with excess biotin, produced essentially no change in device characteristic of the biotinylated polymer-coated devices.
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Citations
Cites
A Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein
Ostuni, E., Chapman, R. G., Holmlin, R. E., Takayama, S., & Whitesides, G. M. (2001) · Langmuir · doi:10.1021/la010384m · Cited by 1,799
Cited by
Hammock, M. L., Chortos, A., Tee, B. C. ‐., Tok, J. B. ‐., & Bao, Z. (2013) · Advanced Materials · doi:10.1002/adma.201302240 · Cited by 2,396
A dielectric-modulated field-effect transistor for biosensing
Im, H., Huang, X.-J., Gu, B., & Choi, Y.-K. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.180 · Cited by 635
Carbon Nanotube/Polythiophene Chemiresistive Sensors for Chemical Warfare Agents
Wang, F., Gu, H., & Swager, T. M. (2008) · Journal of the American Chemical Society · doi:10.1021/ja710795k · Cited by 391
Nernst Limit in Dual-Gated Si-Nanowire FET Sensors
Knopfmacher, O., Tarasov, A., Fu, W., Wipf, M., Niesen, B., Calame, M., & Schönenberger, C. (2010) · Nano Letters · doi:10.1021/nl100892y · Cited by 353
Metadata
- Authors
- Star, A., Gabriel, J.-C. P., Bradley, K., & Grüner, G.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-03-05
- Volume
- 3
- Issue
- 4
- Pages
- 459-463
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2135331413
- Cited by
- 771
- References
- 1
- FWCI
- 38.55
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
