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Six-Helix Bundles Designed from DNA
Open accessAbstract
We present a designed cyclic DNA motif that consists of six DNA double helices that are connected to each other at two crossover sites. DNA double helices with 10.5 nucleotide pairs per turn facilitate the programming of DNA double crossover molecules to form hexagonally symmetric arrangements when the crossover points are separated by seven or fourteen nucleotide pairs. We demonstrate by atomic force microscopy well-formed arrays of hexagonal six-helix bundle motifs both in 1D and in 2D.
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Citations
Cited by
Seeman, N. C., & Sleiman, H. F. (2017) · Nature Reviews Materials · doi:10.1038/natrevmats.2017.68 · Cited by 1,875
Self-citationProgrammable materials and the nature of the DNA bond
Jones, M. R., Seeman, N. C., & Mirkin, C. A. (2015) · Science · doi:10.1126/science.1260901 · Cited by 1,347
Self-citationChallenges and opportunities for structural DNA nanotechnology
Pinheiro, A. V., Han, D., Shih, W. M., & Yan, H. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.187 · Cited by 1,292
Seeman, N. C. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060308-102244 · Cited by 992
Self-citationVirus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability
Perrault, S. D., & Shih, W. M. (2014) · ACS Nano · doi:10.1021/nn5011914 · Cited by 522
Metadata
- Authors
- Mathieu, F., Liao, S., Kopatsch, J., Wang, T., Mao, C., & Seeman, N. C.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-03-02
- Volume
- 5
- Issue
- 4
- Pages
- 661-665
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2041281044
- Cited by
- 315
- References
- 0
- FWCI
- 7.61
- Type
- journal article
- Language
- en
- Open access
- green
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- Mathieu, F., Liao, S., Kopatsch, J., Wang, T., Mao, C., & Seeman, N. C. (2005). Six-Helix Bundles Designed from DNA. Nano Letters. https://doi.org/10.1021/nl050084f
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