The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
A Cellular Trojan Horse for Delivery of Therapeutic Nanoparticles into Tumors
Abstract
Destruction of hypoxic regions within tumors, virtually inaccessible to cancer therapies, may well prevent malignant progression. The tumor's recruitment of monocytes into these regions may be exploited for nanoparticle-based delivery. Monocytes containing therapeutic nanoparticles could serve as "Trojan Horses" for nanoparticle transport into these tumor regions. Here we report the demonstration of several key steps toward this therapeutic strategy: phagocytosis of Au nanoshells, and photoinduced cell death of monocytes/macrophages as isolates and within tumor spheroids.
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Cites
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A Hybridization Model for the Plasmon Response of Complex Nanostructures
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Self-citationNanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
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Self-citationNanoengineering of optical resonances
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Self-citationDistinct role of macrophages in different tumor microenvironments
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Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles
O'Neal, D. P., Hirsch, L. R., Halas, N. J., Payne, J. D., & West, J. L. (2004) · Cancer Letters · doi:10.1016/j.canlet.2004.02.004 · Cited by 1,849
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Cited by
Cancer nanomedicine: progress, challenges and opportunities
Shi, J., Kantoff, P. W., Wooster, R., & Farokhzad, O. C. (2017) · Nature Reviews Cancer · doi:10.1038/nrc.2016.108 · Cited by 5,873
Nanoparticle PEGylation for Imaging and Therapy
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Nanoshell-Enabled Photothermal Cancer Therapy: Impending Clinical Impact
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Self-citationBio-inspired, bioengineered and biomimetic drug delivery carriers
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Templated Techniques for the Synthesis and Assembly of Plasmonic Nanostructures
Jones, M. R., Osberg, K. D., Macfarlane, R. J., Langille, M. R., & Mirkin, C. A. (2011) · Chemical Reviews · doi:10.1021/cr1004452 · Cited by 1,159
Metadata
- Authors
- Choi, M.-R., Stanton-Maxey, K. J., Stanley, J. K., Levin, C. S., Bardhan, R., Akin, D., Badve, S., Sturgis, J., Robinson, J. P., Bashir, R., Halas, N. J., & Clare, S. E.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-11-03
- Volume
- 7
- Issue
- 12
- Pages
- 3759-3765
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2131430454
- Cited by
- 584
- References
- 24
- FWCI
- 15.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- Choi, M.-R., Stanton-Maxey, K. J., Stanley, J. K., Levin, C. S., Bardhan, R., Akin, D., Badve, S., Sturgis, J., Robinson, J. P., Bashir, R., Halas, N. J., & Clare, S. E. (2007). A Cellular Trojan Horse for Delivery of Therapeutic Nanoparticles into Tumors. Nano Letters. https://doi.org/10.1021/nl072209h
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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