Cited by 208Photoacoustic and Ultrasonic ImagingGold and Silver Nanoparticles Synthesis and ApplicationsNanoplatforms for cancer theranostics

Plasmonic Intravascular Photoacoustic Imaging for Detection of Macrophages in Atherosclerotic Plaques

Wang, Bo, Yantsen, Evgeniya, Larson, Timothy, Karpiouk, Andrei B., Sethuraman, Shriram, Su, Jimmy L., Sokolov, Konstantin, Emelianov, Stanislav Y.·2009·Nano Letters

Abstract

To detect macrophages in atherosclerotic plaques, plasmonic gold nanoparticles are introduced as a contrast agent for intravascular photoacoustic imaging. The phantom and ex vivo tissue studies show that the individual spherical nanoparticles, resonant at 530 nm wavelength, produce a weak photoacoustic signal at 680 nm wavelength while photoacoustic signal from nanoparticles internalized by macrophages is very strong due to the plasmon resonance coupling effect. These results suggest that intravascular photoacoustic imaging can assess the macrophage-mediated aggregation of nanoparticles and therefore identify the presence and the location of nanoparticles associated with macrophage-rich atherosclerotic plaques.

Integrity signals

Registry

Crossref · 10.1021/nl801852e

Cites

35 of 35 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Imaging centrally located blood vessels with optical techniques and ultrasound has necessitated development of invasive catheter-based imaging systems.

    “Therefore, imaging centrally located blood vessels with optical techniques and ultrasound has necessitated the development of invasive catheter-based imaging systems153.”

Cites

Flagged first, then by citations

Research works printed but not linked: 2

  1. Chen W. Q., 2007, Am. J. Physiol.: Heart Circ. Physiol., 293, H2836
  2. Emelianov S. Y., 2006, Proc. - IEEE Ultrason. Symp., 405

Cited by

Sorted by citations

Authors
Wang, B., Yantsen, E., Larson, T., Karpiouk, A. B., Sethuraman, S., Su, J. L., Sokolov, K., & Emelianov, S. Y.
Affiliations
The University of Texas MD Anderson Cancer Center (US)
Corresponding author
Emelianov, Stanislav Y.
Venue
Nano Letters
Published
2008-10-10
Volume
9
Issue
6
Pages
2212-2217
ISSN
  • 1530-6984 (ISSN-L)
  • 1530-6992
OpenAlex
W2075244150
Cited by
208
References
35
Citations by year
2026: 2 · 2025: 8 · 2024: 8 · 2023: 4 · 2022: 10 · 2021: 9 · 2020: 11 · 2019: 12 · 2018: 12 · 2017: 14 · 2016: 22 · 2015: 9 · 2014: 19 · 2013: 15 · 2012: 19
FWCI
7.51
Type
journal article
Language
en
Open access
closed
Locations
  • Nano Letters (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Heart, Lung, and Blood Institute (HL084076, R21HL084076)
  • National Institute of Biomedical Imaging and Bioengineering (R21EB004963, EB 004963)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Photoacoustic and Ultrasonic Imaging
  • Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
Keywords
intravascular photoacoustic imaging, plasmonic gold nanoparticles, macrophages, atherosclerotic plaque, nanoparticle contrast agents, plasmon resonance, nanoparticle uptake, nanoparticle aggregation
MeSH terms
Acoustics, Animals, Blood Vessels, Contrast Media, Gold, Macrophages, Phantoms, Imaging, Surface Plasmon Resonance, Atherosclerosis, Mice, Metal Nanoparticles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review