The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery
Abstract
Although uptake into cells is highly complex and regulated, heterogeneous particle collectives are usually employed to deliver small interfering RNA (siRNA) to cells. Within these collectives, it is difficult to accurately identify the active species, and a decrease in efficacy is inherent to such preparations. Here, we demonstrate the manufacture of uniform nanoparticles with the deposition of siRNA on gold in a layer-by-layer approach, and we further report on the cellular delivery and siRNA activity as functions of surface properties.
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Citations
Cites
Knocking down barriers: advances in siRNA delivery
Whitehead, K. A., Langer, R., & Anderson, D. G. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2742 · Cited by 3,115
Cited by
Xia, T., Kovochich, M., Liong, M., Meng, H., Kabehie, S., George, S., Zink, J. I., & Nel, A. E. (2009) · ACS Nano · doi:10.1021/nn900918w · Cited by 933
Gold Nanoparticles for Nucleic Acid Delivery
Ding, Y., Jiang, Z., Saha, K., Kim, C. S., Kim, S. T., Landis, R. F., & Rotello, V. M. (2014) · Molecular Therapy · doi:10.1038/mt.2014.30 · Cited by 521
Layer-by-Layer Nanoparticles with a pH-Sheddable Layer for in Vivo Targeting of Tumor Hypoxia
Poon, Z., Chang, D., Zhao, X., & Hammond, P. T. (2011) · ACS Nano · doi:10.1021/nn200876f · Cited by 343
Han, X., Li, Y., Xu, Y., Zhao, X., Zhang, Y., Yang, X., Wang, Y., Zhao, R., Anderson, G. J., Zhao, Y., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05906-x · Cited by 339
Biomaterials for mRNA delivery
Islam, M. A., Reesor, E. K. G., Xu, Y., Zope, H. R., Zetter, B. R., & Shi, J. (2015) · Biomaterials Science · doi:10.1039/c5bm00198f · Cited by 176
Metadata
- Authors
- Elbakry, A., Zaky, A., Liebl, R., Rachel, R., Goepferich, A., & Breunig, M.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-03-30
- Volume
- 9
- Issue
- 5
- Pages
- 2059-2064
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2064614508
- Cited by
- 425
- References
- 1
- FWCI
- 12.00
- Type
- journal article
- Language
- en
- Open access
- closed
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- Elbakry, A., Zaky, A., Liebl, R., Rachel, R., Goepferich, A., & Breunig, M. (2009). Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery. Nano Letters. https://doi.org/10.1021/nl9003865
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
