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Temperature Sensing Using Fluorescent Nanothermometers
Open accessAbstract
Acquiring the temperature of a single living cell is not a trivial task. In this paper, we devise a novel nanothermometer, capable of accurately determining the temperature of solutions as well as biological systems such as HeLa cancer cells. The nanothermometer is based on the temperature-sensitive fluorescence of NaYF(4):Er(3+),Yb(3+) nanoparticles, where the intensity ratio of the green fluorescence bands of the Er(3+) dopant ions ((2)H(11/2) --> (4)I(15/2) and (4)S(3/2) --> (4)I(15/2)) changes with temperature. The nanothermometers were first used to obtain thermal profiles created when heating a colloidal solution of NaYF(4):Er(3+),Yb(3+) nanoparticles in water using a pump-probe experiment. Following incubation of the nanoparticles with HeLa cervical cancer cells and their subsequent uptake, the fluorescent nanothermometers measured the internal temperature of the living cell from 25 degrees C to its thermally induced death at 45 degrees C.
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Citations
Cited by
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
Chen, G., Qiu, H., Prasad, P. N., & Chen, X. (2014) · Chemical Reviews · doi:10.1021/cr400425h · Cited by 2,699
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Wang, X.-D., Wolfbeis, O. S., & Meier, R. J. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60102a · Cited by 1,647
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Cui, Y., Xu, H., Yue, Y., Guo, Z., Yu, J., Chen, Z., Gao, J., Yang, Y., Qian, G., & Chen, B. (2012) · Journal of the American Chemical Society · doi:10.1021/ja2108036 · Cited by 1,161
High-Precision Nanoscale Temperature Sensing Using Single Defects in Diamond
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Mapping Intracellular Temperature Using Green Fluorescent Protein
Donner, J. S., Thompson, S. A., Kreuzer, M. P., Baffou, G., & Quidant, R. (2012) · Nano Letters · doi:10.1021/nl300389y · Cited by 441
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Rocha, U., Jacinto da Silva, C., Ferreira Silva, W., Guedes, I., Benayas, A., Martínez Maestro, L., Acosta Elias, M., Bovero, E., van Veggel, F. C. J. M., García Solé, J. A., et al. (2013) · ACS Nano · doi:10.1021/nn304373q · Cited by 382
Self-citationIn Vivo Luminescence Nanothermometry: from Materials to Applications
del Rosal, B., Ximendes, E., Rocha, U., & Jaque, D. (2017) · Advanced Optical Materials · doi:10.1002/adom.201600508 · Cited by 331
Self-citationLiu, S., Yan, L., Huang, J., Zhang, Q., & Zhou, B. (2022) · Chemical Society Reviews · doi:10.1039/d1cs00753j · Cited by 298
Ke, G., Wang, C., Ge, Y., Zheng, N., Zhu, Z., & Yang, C. J. (2012) · Journal of the American Chemical Society · doi:10.1021/ja3082439 · Cited by 196
Mohammed, L. J., & Omer, K. M. (2020) · Scientific Reports · doi:10.1038/s41598-020-59958-5 · Cited by 154
Petrini, G., Moreva, E., Bernardi, E., Traina, P., Tomagra, G., Carabelli, V., Degiovanni, I. P., & Genovese, M. (2020) · Advanced Quantum Technologies · doi:10.1002/qute.202000066 · Cited by 63
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Metadata
- Authors
- Vetrone, F., Naccache, R., Zamarrón, A., Juarranz de la Fuente, A., Sanz-Rodríguez, F., Martinez Maestro, L., Martín Rodriguez, E., Jaque, D., García Solé, J., & Capobianco, J. A.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-05-04
- Volume
- 4
- Issue
- 6
- Pages
- 3254-3258
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2030395871
- Cited by
- 1,505
- References
- 0
- FWCI
- 22.39
- Type
- journal article
- Language
- en
- Open access
- green
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