The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Functionalized Ultrasound-Propelled Magnetically Guided Nanomotors: Toward Practical Biomedical Applications
Abstract
Magnetically guided ultrasound-powered nanowire motors, functionalized with bioreceptors and a drug-loaded polymeric segment, are described for "capture and transport" and drug-delivery processes. These high-performance fuel-free motors display advanced capabilities and functionalities, including magnetic guidance, coordinated aligned movement, cargo towing, capture and isolation of biological targets, drug delivery, and operation in real-life biological and environmental media. The template-prepared three-segment Au-Ni-Au nanowire motors are propelled acoustically by mechanical waves produced by a piezoelectric transducer. An embedded nickel segment facilitates a magnetically guided motion as well as transport of large "cargo" along predetermined trajectories. Substantial improvement in the speed and power is realized by the controlled concavity formation at the end of the motor nanowire using a sphere lithography protocol. Functionalization of the Au segments with lectin and antiprotein A antibody bioreceptors allows capture and transport of E. coli and S. aureus bacteria, respectively. Potential therapeutic applications are illustrated in connection to the addition of a pH-sensitive drug-loaded polymeric (PPy-PSS) segment. The attractive capabilities of these fuel-free acoustically driven functionalized Au-Ni-Au nanowires, along with the simple preparation procedure and minimal adverse effects of ultrasonic waves, make them highly attractive for diverse in vivo biomedical applications.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Microrobots for Minimally Invasive Medicine
Nelson, B. J., Kaliakatsos, I. K., & Abbott, J. J. (2010) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-010510-103409 · Cited by 1,968
Controlled Propulsion of Artificial Magnetic Nanostructured Propellers
Ghosh, A., & Fischer, P. (2009) · Nano Letters · doi:10.1021/nl900186w · Cited by 1,296
Autonomous Motion of Metallic Microrods Propelled by Ultrasound
Wang, W., Castro, L. A., Hoyos, M., & Mallouk, T. E. (2012) · ACS Nano · doi:10.1021/nn301312z · Cited by 736
Nano/Microscale Motors: Biomedical Opportunities and Challenges
Wang, J., & Gao, W. (2012) · ACS Nano · doi:10.1021/nn3028997 · Cited by 668
Self-citationRolled-up nanotech on polymers: from basic perception to self-propelled catalytic microengines
Mei, Y., Solovev, A. A., Sanchez, S., & Schmidt, O. G. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00078g · Cited by 650
Gao, W., Sattayasamitsathit, S., Orozco, J., & Wang, J. (2011) · Journal of the American Chemical Society · doi:10.1021/ja203773g · Cited by 542
Self-citationOzin, G. A., Manners, I., Fournier‐Bidoz, S., & Arsenault, A. (2005) · Advanced Materials · doi:10.1002/adma.200501767 · Cited by 538
Paxton, W. F., Sundararajan, S., Mallouk, T. E., & Sen, A. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200600060 · Cited by 536
Catalytic Nanomotors: Remote‐Controlled Autonomous Movement of Striped Metallic Nanorods
Kline, T. R., Paxton, W. F., Mallouk, T. E., & Sen, A. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200461890 · Cited by 503
Characterizing the Swimming Properties of Artificial Bacterial Flagella
Zhang, L., Abbott, J. J., Dong, L., Peyer, K. E., Kratochvil, B. E., Zhang, H., Bergeles, C., & Nelson, B. J. (2009) · Nano Letters · doi:10.1021/nl901869j · Cited by 489
Electric field-induced chemical locomotion of conducting objects
Loget, G., & Kuhn, A. (2011) · Nature Communications · doi:10.1038/ncomms1550 · Cited by 475
Nanomachines: Fundamentals and Applications
(2013) · Wiley eBooks · doi:10.1002/9783527651450 · Cited by 470
Can Man-Made Nanomachines Compete with Nature Biomotors?
Wang, J. (2009) · ACS Nano · doi:10.1021/nn800829k · Cited by 437
Self-citationMagnetically Powered Flexible Metal Nanowire Motors
Gao, W., Sattayasamitsathit, S., Manesh, K. M., Weihs, D., & Wang, J. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1072349 · Cited by 416
Self-citationBacterial Isolation by Lectin-Modified Microengines
Campuzano, S., Orozco, J., Kagan, D., Guix, M., Gao, W., Sattayasamitsathit, S., Claussen, J. C., Merkoçi, A., & Wang, J. (2012) · Nano Letters · doi:10.1021/nl203717q · Cited by 330
Self-citationRemotely powered self-propelling particles and micropumps based on miniature diodes
Chang, S. T., Paunov, V. N., Petsev, D. N., & Velev, O. D. (2007) · Nature Materials · doi:10.1038/nmat1843 · Cited by 314
Mallouk, T. E., & Sen, A. (2009) · Scientific American · doi:10.1038/scientificamerican0509-72 · Cited by 293
Rapid Delivery of Drug Carriers Propelled and Navigated by Catalytic Nanoshuttles
Kagan, D., Laocharoensuk, R., Zimmerman, M., Clawson, C., Balasubramanian, S., Kang, D., Bishop, D., Sattayasamitsathit, S., Zhang, L., & Wang, J. (2010) · Small · doi:10.1002/smll.201001257 · Cited by 290
Self-citationBhasikuttan, A. C., Mohanty, J., Nau, W. M., & Pal, H. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200604757 · Cited by 215
Bhasikuttan, A. C., Mohanty, J., Nau, W. M., & Pal, H. (2007) · Angewandte Chemie · doi:10.1002/ange.200604757 · Cited by 197
Fuel for Thought: Chemically Powered Nanomotors Out-Swim Nature’s Flagellated Bacteria
Mirkovic, T., Zacharia, N. S., Scholes, G. D., & Ozin, G. A. (2010) · ACS Nano · doi:10.1021/nn100669h · Cited by 188
Motion-driven sensing and biosensing using electrochemically propelled nanomotors
Campuzano, S., Kagan, D., Orozco, J., & Wang, J. (2011) · The Analyst · doi:10.1039/c1an15599g · Cited by 161
Self-citationElectrochemically powered self-propelled electrophoretic nanosubmarines
Pumera, M. (2010) · Nanoscale · doi:10.1039/c0nr00287a · Cited by 149
Cited by
Enzymatically active biomimetic micropropellers for the penetration of mucin gels
Walker, D., Käsdorf, B. T., Jeong, H.-H., Lieleg, O., & Fischer, P. (2015) · Science Advances · doi:10.1126/sciadv.1500501 · Cited by 331
Mimicking the Cell: Bio-Inspired Functions of Supramolecular Assemblies
Tu, Y., Peng, F., Adawy, A., Men, Y., Abdelmohsen, L. K. E. A., & Wilson, D. A. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00344 · Cited by 316
Xu, T., Soto, F., Gao, W., Dong, R., Garcia-Gradilla, V., Magaña, E., Zhang, X., & Wang, J. (2015) · Journal of the American Chemical Society · doi:10.1021/ja511012v · Cited by 304
Self-citationUltrasound-responsive systems as components for smart materials
Athanassiadis, A. G., Ma, Z., Moreno-Gomez, N., Melde, K., Choi, E., Goyal, R., & Fischer, P. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00622 · Cited by 293
Liu, L., Chen, B., Liu, K., Gao, J., Ye, Y., Wang, Z., Qin, N., Wilson, D. A., Tu, Y., & Peng, F. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201910108 · Cited by 150
Metadata
- Authors
- Garcia-Gradilla, V., Orozco, J., Sattayasamitsathit, S., Soto, F., Kuralay, F., Pourazary, A., Katzenberg, A., Gao, W., Shen, Y., & Wang, J.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-08-28
- Volume
- 7
- Issue
- 10
- Pages
- 9232-9240
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2320560325
- Cited by
- 438
- References
- 23
- FWCI
- 19.77
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
