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Cited by 433

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Layer-by-Layer-Coated Gelatin Nanoparticles as a Vehicle for Delivery of Natural Polyphenols

Shutava, Tatsiana G., Balkundi, Shantanu S., Vangala, Pranitha, Steffan, Joshua J., Bigelow, Rebecca L., Cardelli, James A., O’Neal, D. Patrick, Lvov, Yuri M.·2009·ACS Nano

Abstract

Natural polyphenols with previously demonstrated anticancer potential, epigallocatechin gallate (EGCG), tannic acid, curcumin, and theaflavin, were encased into gelatin-based 200 nm nanoparticles consisting of a soft gel-like interior with or without a surrounding LbL shell of polyelectrolytes (polystyrene sulfonate/polyallylamine hydrochloride, polyglutamic acid/poly-l-lysine, dextran sulfate/protamine sulfate, carboxymethyl cellulose/gelatin, type A) assembled using the layer-by-layer technique. The characteristics of polyphenol loading and factors affecting their release from the nanocapsules were investigated. Nanoparticle-encapsulated EGCG retained its biological activity and blocked hepatocyte growth factor (HGF)-induced intracellular signaling in the breast cancer cell line MBA-MD-231 as potently as free EGCG.

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Crossref · 10.1021/nn900451a

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Metadata

Authors
Shutava, T. G., Balkundi, S. S., Vangala, P., Steffan, J. J., Bigelow, R. L., Cardelli, J. A., O’Neal, D. P., & Lvov, Y. M.
Venue
ACS Nano
Published
2009-06-17
Volume
3
Issue
7
Pages
1877-1885
ISSN
  • 1936-0851 (ISSN-L)
  • 1936-086X
OpenAlex
W2080082999
Cited by
433
References
2
FWCI
11.08
Type
journal article
Language
en
Open access
closed

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