The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Layer-by-Layer-Coated Gelatin Nanoparticles as a Vehicle for Delivery of Natural Polyphenols
Abstract
Natural polyphenols with previously demonstrated anticancer potential, epigallocatechin gallate (EGCG), tannic acid, curcumin, and theaflavin, were encased into gelatin-based 200 nm nanoparticles consisting of a soft gel-like interior with or without a surrounding LbL shell of polyelectrolytes (polystyrene sulfonate/polyallylamine hydrochloride, polyglutamic acid/poly-l-lysine, dextran sulfate/protamine sulfate, carboxymethyl cellulose/gelatin, type A) assembled using the layer-by-layer technique. The characteristics of polyphenol loading and factors affecting their release from the nanocapsules were investigated. Nanoparticle-encapsulated EGCG retained its biological activity and blocked hepatocyte growth factor (HGF)-induced intracellular signaling in the breast cancer cell line MBA-MD-231 as potently as free EGCG.
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Cites
Cancer chemoprevention with dietary phytochemicals
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Tannin−Protein Complexes as Radical Scavengers and Radical Sinks
Riedl, K. M., & Hagerman, A. E. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010683h · Cited by 262
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Overview of metabolism and bioavailability enhancement of polyphenols
Lewandowska, U., Szewczyk, K., Hrabec, E., Janecka, A., & Gorlach, S. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf404439b · Cited by 196
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Metadata
- Authors
- Shutava, T. G., Balkundi, S. S., Vangala, P., Steffan, J. J., Bigelow, R. L., Cardelli, J. A., O’Neal, D. P., & Lvov, Y. M.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-06-17
- Volume
- 3
- Issue
- 7
- Pages
- 1877-1885
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2080082999
- Cited by
- 433
- References
- 2
- FWCI
- 11.08
- Type
- journal article
- Language
- en
- Open access
- closed
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