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Tyrosinase Inhibitors from Anacardium occidentale Fruits
Abstract
Anacardic acids, 2-methylcardols, and cardols isolated from various parts of the cashew [Anacardium occidentale] (Anacardiaceae) fruit have been found to exhibit tyrosinase inhibitory activity. Kinetic studies with the two principal active compounds, 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid and 5-[8(Z),11(Z),14-pentadecatrienyl]resorcinol, have indicated that both of these phenolic compounds exhibit characteristic competitive inhibition of the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) by mushroom tyrosinase.
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Metadata
- Authors
- Kubo, I., Kinst-Hori, I., & Yokokawa, Y.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 1994-04
- Volume
- 57
- Issue
- 4
- Pages
- 545-551
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W2056553554
- Cited by
- 179
- References
- 0
- FWCI
- 0.12
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kubo, I., Kinst-Hori, I., & Yokokawa, Y. (1994). Tyrosinase Inhibitors from Anacardium occidentale Fruits. Journal of Natural Products. https://doi.org/10.1021/np50106a021
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