Antihyperglycemic Effect of Catalpol in Streptozotocin-Induced Diabetic Rats

Arginine metabolism: nitric oxide and beyond

WU, G., & MORRIS, S. M. (1998) · Biochemical Journal · doi:10.1042/bj3360001 · Cited by 2,811 · see citing works

Rehmannia glutinosa: Review of botany, chemistry and pharmacology

Zhang, R., Li, M., & Jia, Z. (2008) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2008.02.018 · Cited by 413 · see citing works

Variations in Insulin-Stimulated Glucose Uptake in Healthy Individuals with Normal Glucose Tolerance*

Hollenbeck, C. B., & Reaven, G. M. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-6-1169 · Cited by 306 · see citing works

Glucose Transport Is Rate Limiting for Skeletal Muscle Glucose Metabolism in Normal and STZ-Induced Diabetic Rats

Ziel, F. H., Venkatesan, N., & Davidson, M. B. (1988) · Diabetes · doi:10.2337/diab.37.7.885 · Cited by 208 · see citing works

Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes.

Rossetti, L., Giaccari, A., Barzilai, N., Howard, K., Sebel, G., & Hu, M. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116681 · Cited by 186 · see citing works

Role of glucokinase and glucose-6-phosphatase in the acute and chronic regulation of hepatic glucose fluxes by insulin.

Barzilai, N., & Rossetti, L. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74566-9 · Cited by 162 · see citing works

Novel Mechanism for Plasma Glucose–Lowering Action of Metformin in Streptozotocin-Induced Diabetic Rats

Cheng, J., Huang, C.-C., Liu, I.-M., Tzeng, T., & Chang, C. J. (2006) · Diabetes · doi:10.2337/diabetes.55.03.06.db05-0934 · Cited by 152 · see citing works

Near-infrared light via light-emitting diode treatment is therapeutic against rotenone- and 1-methyl-4-phenylpyridinium ion-induced neurotoxicity

Liang, H., Whelan, H. T., Eells, J. T., & Wong‐Riley, M. T. T. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.03.042 · Cited by 150 · see citing works

Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism

Zhang, R., Zhou, J.-H., Jia, Z., Zhang, Y., & Gu, G. (2003) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2003.09.018 · Cited by 144 · see citing works

The enzymic isolation of adult rat hepatocytes in a functional and viable state

Fry, J. R., Jones, C., Wiebkin, P., Bellemann, P., & Bridges, J. W. (1976) · Analytical Biochemistry · doi:10.1016/s0003-2697(76)80003-6 · Cited by 138 · see citing works

Hydrogen Peroxide Activates NF κ B and the Interleukin-6 Promoter Through NF κ B-Inducing Kinase

Zhang, J., Johnston, G., Stebler, B. S., & Keller, E. T. (2001) · Antioxidants and Redox Signaling · doi:10.1089/15230860152409121 · Cited by 125 · see citing works

Plasma Glucose–Lowering Effect of Tramadol in Streptozotocin-Induced Diabetic Rats

Cheng, J., Liu, I.-M., Chi, T.-C., Tzeng, T., Lu, F.-H., & Chang, C. J. (2001) · Diabetes · doi:10.2337/diabetes.50.12.2815 · Cited by 117 · see citing works

Antihyperglycemic action of isoferulic acid in streptozotocin‐induced diabetic rats

Liu, I., Hsu, F.-L., Chen, C.-F., & Cheng, J.-T. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703082 · Cited by 92 · see citing works

Pathogenesis and treatment of hypertension associated with diabetes mellitus

Weidmann, P. U., Böhlen, L., & de Courten, M. (1993) · American Heart Journal · doi:10.1016/0002-8703(93)90447-h · Cited by 83 · see citing works

Iridoid glycosides of Rehmannia glutinosa

Oshio, H., & Inouye, H. (1982) · Phytochemistry · doi:10.1016/0031-9422(82)80029-0 · Cited by 71 · see citing works

Diabetic Nephropathy

Goldstein, D. A., & Massry, S. G. (2008) · ˜The œNephron journals/Nephron journals · doi:10.1159/000181239 · Cited by 64 · see citing works

New Iridoid Glucosides and a Lignan Diglucoside from Globularia alypum L

Chaudhuri, R. K., & Sticher, O. (1981) · Helvetica Chimica Acta · doi:10.1002/hlca.19810640103 · Cited by 56 · see citing works

Isoferulic acid as active principle from the rhizoma of Cimicifuga dahurica to lower plasma glucose in diabetic rats.

Liu, I.-M., Chi, T., Hsu, F.-L., Chen, C.-F., & Cheng, J.-T. (1999) · Planta Medica · doi:10.1055/s-1999-14048 · Cited by 55 · see citing works

Antihyperglycemic action of angiotensin II receptor antagonist, valsartan, in streptozotocin-induced diabetic rats

Chan, P., Wong, K., Liu, I.-M., Tzeng, T., Yang, T.-L., & Cheng, J. (2003) · Journal of Hypertension · doi:10.1097/00004872-200304000-00020 · Cited by 44 · see citing works

Catalpol attenuates nitric oxide increase via ERK signaling pathways induced by rotenone in mesencephalic neurons

Bi, J., Jiang, B., Hao, S., Zhang, A., Dong, Y., Jiang, T., & An, L. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.12.003 · Cited by 35 · see citing works

An efficient approach for the synthesis of the hexahydroazepine segment of balanol

Yadav, J. S., & Srinivas, C. (2002) · Tetrahedron Letters · doi:10.1016/s0040-4039(02)00681-0 · Cited by 34 · see citing works

Picroside I : A bitter principle of picrorhiza kurrooa

Kitagawa, I., Hino, K., Nishimura, T., Mukai, E., Yosioka, I., Inouye, H., & Yoshida, T. (1969) · Tetrahedron Letters · doi:10.1016/s0040-4039(01)88526-9 · Cited by 32 · see citing works

Aquaticol, a Bis-Sesquiterpene and Iridoid Glucosides from Veronica anagallis-aquatica

Su, B., Li, Y., Gao, K., & Jia, Z. (2000) · Planta Medica · doi:10.1055/s-2000-8564 · Cited by 26 · see citing works

Diabetes is an inflammatory disease: evidence from traditional Chinese medicines

Xie, W., & Du, L. (2010) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2010.01336.x · Cited by 305 · see citing works

Functional Silver Nanoparticle as a Benign Antimicrobial Agent That Eradicates Antibiotic-Resistant Bacteria and Promotes Wound Healing

Dai, X., Guo, Q., Zhao, Y., Zhang, P., Zhang, T., Zhang, X., & Li, C. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b09267 · Cited by 213 · see citing works

Naturally Occurring Iridoids and Secoiridoids. An Updated Review, Part 4

Dinda, B., Debnath, S., & Banik, R. (2011) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.59.803 · Cited by 164 · see citing works

Immunoenhancement effect of rehmannia glutinosa polysaccharide on lymphocyte proliferation and dendritic cell

Huang, Y., Jiang, C., Hu, Y., Zhao, X., Shi, C., Yu, Y., Liu, C., Tao, Y., Pan, H., Feng, Y., et al. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2013.04.018 · Cited by 134 · see citing works

Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice

Zhou, J., Xu, G., Yan, J., Li, K., Bai, Z., Cheng, W., & Huang, K. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2015.02.026 · Cited by 120 · see citing works

A systematic review on botany, processing, application, phytochemistry and pharmacological action of Radix Rehmnniae

Li, M., Jiang, H., Hao, Y., Du, K., Du, H., Ma, C., Tu, H., & He, Y. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114820 · Cited by 118 · see citing works

Multiple Biological Effects of an Iridoid Glucoside, Catalpol, and Its Underlying Molecular Mechanisms

Bhattamisra, S. K., Yap, K. H., Rao, V., & Choudhury, H. (2019) · Biomolecules · doi:10.3390/biom10010032 · Cited by 106 · see citing works

Plasma Glucose Lowering Mechanisms of Catalpol, an Active Principle from Roots of Rehmannia glutinosa, in Streptozotocin-Induced Diabetic Rats

Shieh, J., Cheng, K., Chung, H.-H., Kerh, Y.-F., Yeh, C., & Cheng, J. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf200069t · Cited by 102 · see citing works

Antidiabetic Potential of Monoterpenes: A Case of Small Molecules Punching above Their Weight

Habtemariam, S. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms19010004 · Cited by 100 · see citing works

Catalpol Ameliorates High-Fat Diet-Induced Insulin Resistance and Adipose Tissue Inflammation by Suppressing the JNK and NF-Κb Pathways

Zhou, J., Xu, G., Ma, S., Li, F., Yuan, M., Xu, H., & Huang, K. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.10.054 · Cited by 97 · see citing works

Catalpol stimulates VEGF production via the JAK2/STAT3 pathway to improve angiogenesis in rats’ stroke model

Wan, D., Yang, X. Q., Wang, Y., Zhu, H., Wang, T., Zhiqiang, L., Shan, F., Ya, F., Wang, H., Jinghuan, W., et al. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.06.030 · Cited by 95 · see citing works

Catalpol in Diabetes and its Complications: A Review of Pharmacology, Pharmacokinetics, and Safety

Bai, Y., Zhu, R., Tian, Y., Li, R., Chen, B., Zhang, H., Xia, B., Zhao, D., Mo, F., Zhang, D., et al. (2019) · Molecules · doi:10.3390/molecules24183302 · Cited by 88 · see citing works

Antidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high-sugar feed

Zhu, H., Wang, Y., Liu, Z., Wang, J., Wan, D., Feng, S., Yang, X. Q., & Wang, T. (2016) · Chinese Medicine · doi:10.1186/s13020-016-0096-7 · Cited by 78 · see citing works

Exploring the Therapeutic Potential of Phytochemicals in Alzheimer’s Disease: Focus on Polyphenols and Monoterpenes

Piccialli, I., Tedeschi, V., Caputo, L., D’Errico, S., Ciccone, R., De Feo, V., Secondo, A., & Pannaccione, A. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.876614 · Cited by 73 · see citing works

Hypoglycemic effect of catalpol on high-fat diet/streptozotocin-induced diabetic mice by increasing skeletal muscle mitochondrial biogenesis

Li, X., Xu, Z., Jiang, Z., Sun, L., Ji, J., Miao, J., Zhang, X., Li, X., Huang, S., Wang, T., et al. (2014) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmu065 · Cited by 65 · see citing works

Catalpol suppresses advanced glycation end-products-induced inflammatory responses through inhibition of reactive oxygen species in human monocytic THP-1 cells

Choi, H., Jang, H.-J., Chung, T., Jeong, S.-I., Cha, J., Choi, J.-Y., Han, C. W., Jang, Y., Joo, M., Jeong, H.-S., et al. (2013) · Fitoterapia · doi:10.1016/j.fitote.2013.01.014 · Cited by 64 · see citing works

Rehmannia glutinosa Suppresses Inflammatory Responses Elicited by Advanced Glycation End Products

Baek, G. M. W. S. G., Jang, Y., Jeong, S.-I., Cha, J., Joo, M., Shin, S.-W., Ha, K., & Jeong, H.-S. (2012) · Inflammation · doi:10.1007/s10753-012-9433-x · Cited by 62 · see citing works

Anti-diabetic activities of catalpol in db/db mice

Bao, Q., Shen, X., Li, Q., Gong, C., Nie, M., & Dong, Y. (2016) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2016.20.2.153 · Cited by 57 · see citing works

Effect of catalpol on diabetic nephropathy in rats

Zhao, D., & Chang-xun, C. (2013) · Phytomedicine · doi:10.1016/j.phymed.2013.04.007 · Cited by 53 · see citing works

Bitter Gentian Teas: Nutritional and Phytochemical Profiles, Polysaccharide Characterisation and Bioactivity

Olennikov, D. N., Kashchenko, N. I., Chirikova, N. K., Koryakina, L., & Николаевич, В. Л. (2015) · Molecules · doi:10.3390/molecules201119674 · Cited by 50 · see citing works

Ameliorating effect and potential mechanism of Rehmannia glutinosa oligosaccharides on the impaired glucose metabolism in chronic stress rats fed with high-fat diet

Zhang, R., Zhou, J., Li, M., Ma, H., Qiu, J., Luo, X., & Jia, Z. (2014) · Phytomedicine · doi:10.1016/j.phymed.2013.11.008 · Cited by 45 · see citing works

A new hypoglycemic mechanism of catalpol revealed by enhancing MyoD/MyoG-mediated myogenesis

Xu, D., Wang, L., Jiang, Z., Zhao, G., Hassan, H. M., Sun, L., Fan, S., Zhou, Z., Zhang, L., & Wang, T. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.08.028 · Cited by 42 · see citing works

Catalpol preserves neural function and attenuates the pathology of Alzheimer's disease in mice

Huang, J., WU, J., Xiang, S., Sheng, S., Jiang, Y., Yang, Z., & Hua, F. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4496 · Cited by 37 · see citing works

Antihyperglycemic Effect of Syringaldehyde in Streptozotocin-Induced Diabetic Rats

Huang, C.-H., Chen, M.-F., Chung, H.-H., & Cheng, J. (2012) · Journal of Natural Products · doi:10.1021/np3003723 · Cited by 36 · see citing works

Catalpol ameliorates doxorubicin‑induced inflammation and oxidative stress in H9C2 cells through PPAR‑γ activation

Jiang, Y., & Zhang, Q. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.8743 · Cited by 36 · see citing works

Mitochondrial fusion/fission process involved in the improvement of catalpol on high glucose-induced hepatic mitochondrial dysfunction

Xu, Z., Zhang, L., Li, X., Jiang, Z., Sun, L., Zhao, G., Zhou, G., Zhang, H., Shang, J., & Wang, T. (2015) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmv061 · Cited by 34 · see citing works

Rehmannia glutinosa exhibits anti‐aging effect through maintaining the quiescence and decreasing the senescence of hematopoietic stem cells

Bai, L., Shi, G., Yang, Y., Chen, W., Zhang, L., & Qin, C. (2018) · Animal Models and Experimental Medicine · doi:10.1002/ame2.12034 · Cited by 34 · see citing works

Catalpol suppresses proliferation and facilitates apoptosis of MCF-7 breast cancer cells through upregulating microRNA-146a and downregulating matrix metalloproteinase-16 expression

Liu, C., WU, F., LIU, Y., & Meng, C. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4361 · Cited by 34 · see citing works

Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt

Xu, F., Xiao, H., Liu, R., Yang, Y., Zhang, M., Chen, L., Chen, Z., Liu, P., & Huang, H. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00261 · Cited by 32 · see citing works

Iridoids are natural glycation inhibitors

West, B. J., Deng, S., Uwaya, A., Isami, F., Abe, Y., Yamagishi, S., & Jensen, C. J. (2016) · Glycoconjugate Journal · doi:10.1007/s10719-016-9695-x · Cited by 30 · see citing works

Catalpol ameliorates diabetic atherosclerosis in diabetic rabbits.

Liu, J., Zheng, C.-Z., Hao, X.-P., Zhang, D., Mao, A.-W., & Yuan, P. (2016) · PubMed Central · Cited by 30 · see citing works

Validated LC‐MS method for simultaneous quantitation of catalpol and harpagide in rat plasma: application to a comparative pharmacokinetic study in normal and diabetic rats after oral administration of Zeng‐Ye‐Decoction

Feng, Y., Liu, Z., Peng, Y., Zhang, L., Ju, P., Kai-shun, B., & Chen, X. (2013) · Biomedical Chromatography · doi:10.1002/bmc.2949 · Cited by 26 · see citing works

Screening of a natural compound library identifies emodin, a natural compound from Rheum palmatum Linn that inhibits DPP4

Wang, Z., Yang, L., Hu, F., Wu, P., Zhang, F., Zhang, C., Liu, W., & Li, M. (2017) · PeerJ · doi:10.7717/peerj.3283 · Cited by 25 · see citing works

Putative identification of components in Zengye Decoction and their effects on glucose consumption and lipogenesis in insulin-induced insulin-resistant HepG2 cells

Liu, Z., Kuang, W., Xi Tao, X. U., Li, D., Zhu, W., Zhou, L., & Zhang, X. (2017) · Journal of Chromatography B · doi:10.1016/j.jchromb.2017.12.019 · Cited by 23 · see citing works

Catalpol counteracts the pathology in a mouse model of Duchenne muscular dystrophy by inhibiting the TGF-β1/TAK1 signaling pathway

Xu, D., Zhao, L., Li, S., Huang, X., Li, C., Sun, L., Li, X., Zhang, L., & Jiang, Z. (2020) · Acta Pharmacologica Sinica · doi:10.1038/s41401-020-00515-1 · Cited by 21 · see citing works

Catalpol Alleviates Ang II-Induced Renal Injury Through NF‐κB Pathway and TGF-β1/Smads Pathway

Cong, C., Yuan, X., Hu, Y., Chen, W., Wang, Y., & Tao, L. (2021) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001148 · Cited by 20 · see citing works

Study of Terpenoid Synthesis and Prenyltransferase in Roots of Rehmannia glutinosa Based on iTRAQ Quantitative Proteomics

Chen, P., Wei, X., Qi, Q., Jia, W., Zhao, M., Wang, H., Zhou, Y., & Duan, H. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.693758 · Cited by 19 · see citing works

Ancient Records and Modern Research on the Mechanisms of Chinese Herbal Medicines in the Treatment of Diabetes Mellitus

Zhang, H.-M., Liang, F.-X., & Chen, R. (2015) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2015/747982 · Cited by 19 · see citing works

Two new eremophilane-type sesquiterpenes from the fresh roots of Rehmannia glutinosa

Liu, Y., Cao, Y.-G., Kan, Y., Ren, Y., Zeng, M., Wang, M.-N., He, C., Chen, X., Zheng, X., & Feng, W. (2020) · Phytochemistry Letters · doi:10.1016/j.phytol.2020.12.004 · Cited by 15 · see citing works

Bioactivity, Compounds Isolated, Chemical Qualitative, and Quantitative Analysis of Cymbaria daurica Extracts

Gong, X., Wang, J., Zhang, M., Wang, P., Wang, C., Shi, R., Zang, E., Zhang, M., Zhang, C., & Li, M. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00048 · Cited by 15 · see citing works

Challenges of continuous cropping in Rehmannia glutinosa: Mechanisms and mitigation measures

Gan, T., Yuan, Z., Gustave, W., Luan, T., He, L., Jia, Z., Zhao, X., Wang, S., Deng, Y., Zhang, X., et al. (2025) · Soil & Environmental Health · doi:10.1016/j.seh.2025.100144 · Cited by 14 · see citing works

Bioactive constituents from toxic seed plants in China

Qu, J., Yu, S., Du, D., & Wang, Y.-D. (2013) · RSC Advances · doi:10.1039/c3ra22417a · Cited by 14 · see citing works

Catalpol Ameliorates Neointimal Hyperplasia in Diabetic Rats

Lin, C.-M., Wang, B.-W., Fang, W., Pan, C.-M., Shyu, K., & Hou, S. (2019) · Planta Medica · doi:10.1055/a-0818-3689 · Cited by 14 · see citing works

Prepared Rehmanniae Radix oligosaccharide regulates postprandial and diabetic blood glucose in mice

Chiu, C., Hsu, W., Liu, H., Liu, S., & Lin, Y. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.12.031 · Cited by 13 · see citing works

Synergistic interactions of catalpol and stachyose in STZ-HFD induced diabetic mice: Synergism in regulation of blood glucose, lipids, and hepatic and renal function

Chen, X., Liao, D., Qin, Z., & Li, X. (2018) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2018.05.006 · Cited by 12 · see citing works

Characteristics and kinetics of catalpol degradation and the effect of its degradation products on free radical scavenging

Wen, X.-S., & Wei, G.-D. (2014) · Pharmacognosy Magazine · doi:10.4103/0973-1296.127360 · Cited by 11 · see citing works

Antidiabetic Effects of Carassius auratus Complex Formula in High Fat Diet Combined Streptozotocin‐Induced Diabetic Mice

Wang, Z.-H., Hsu, C., Lin, H., & Chen, J. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/628473 · Cited by 11 · see citing works

Antidiabetic Phytocompounds Acting as Glucose Transport Stimulators

Eddouks, M., Akdad, M., Hassani, R. A. E., Khallouki, F., & Bakri, Y. (2022) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530322666220510093720 · Cited by 11 · see citing works

Catalpol regulates cholinergic nerve system function through effect on choline acetyl-transferase not M receptor affinity

Wang, J.-H., Xie, H., Zhao, T.-K., & Bai, K. (2014) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2014.12.014 · Cited by 10 · see citing works

Stereoselective synthesis of pseudoglycosides catalyzed by TeCl4 under mild conditions

Freitas, J. C. R., Couto, T. R., Soares‐Paulino, A. A., Filho, J. R. D. F., Malvestiti, I., Oliveira, R. A., & Menezes, P. H. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.07.070 · Cited by 9 · see citing works

Stereoselective synthesis of pseudoglycosides catalyzed by TeCl4 under mild conditions

Freitas, J. C. R., Couto, T. R., Soares‐Paulino, A. A., Filho, J. R. D. F., Malvestiti, I., Oliveira, R. A., & Menezes, P. H. (2012) · Tetrahedron · doi:10.1016/j.tet.2012.09.073 · Cited by 9 · see citing works

Development of a Fluorescence Polarization Based High-Throughput Assay to Identify Casitas B-Lineage Lymphoma RING Domain Regulators

Xie, X., Sun, L., Pessetto, Z. Y., Zhao, Y., Zang, Z., Zhong, L., Wu, M., Su, Q., Gao, X., Zan, W., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078042 · Cited by 8 · see citing works

Hydrophilic interaction liquid chromatography-tandem mass spectrometry analysis of oligosaccharides and iridoid glycosides in rat plasma: Pharmacokinetic characterization of previously overlooked oligosaccharides from Radix Rehmanniae

Wang, H., Du, Y., Zhou, C., Wang, Y., & Wang, X. (2025) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2025.116670 · Cited by 7 · see citing works

Catalpol prevents alteration of cholesterol homeostasis in non-alcoholic fatty liver disease via attenuating endoplasmic reticulum stress and NOX4 over-expression

Yan, J., Wang, C., Jin, Y., Meng, Q., Liu, Q., Liu, Z., Liu, K., & Sun, H. (2017) · RSC Advances · doi:10.1039/c6ra26046b · Cited by 7 · see citing works

Pharmacology of Iridoids

Dinda, B. (2019) · Springer eBooks · doi:10.1007/978-3-030-05575-2_5 · Cited by 6 · see citing works

Two new iridoid glycosides from Odontonema cuspidatum and their bioactivities

Refaey, M. S., Hassanein, A., Mostafa, M. A. H., Wanas, A. S., & Ali, A. (2017) · Phytochemistry Letters · doi:10.1016/j.phytol.2017.08.009 · Cited by 6 · see citing works

Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats

Sun, Y., Wen, X.-S., Zhao, Y., Shen, T., Liu, Z., Gao, H., Qiu, S., & Chen, Y. (2013) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2013.08.057 · Cited by 5 · see citing works

Research Progress of Traditional Chinese Medicine in Adjuvant Treatment of Type 1 Diabetes

Luo, J. F., Hu, F., Jia, Z., Zhu, X., Zhou, Y., Hu, C., Yu, L., & Chen, Z. (2025) · Phytotherapy Research · doi:10.1002/ptr.8514 · Cited by 3 · see citing works

Natural hypoglycaemic bioactives: Newer avenues and newer possibilities

Paul, R. K., & Raza, K. (2024) · Phytotherapy Research · doi:10.1002/ptr.8281 · Cited by 3 · see citing works

Iridoid glucosides against Staphylococcus aureus infection and inhibit inflammation on bovine mammary epithelial cells

Zhang, Y., & Xu, P. (2024) · The Thai Journal of Veterinary Medicine · doi:10.56808/2985-1130.3729 · Cited by 3 · see citing works

Transcriptome profiling of Rehmannia glutinosa uncovers ABA/GA antagonism mechanisms in tuberous root initiation

Yang, R., Du, Y., Fang, Z.-X., Wang, H., Yang, Q., Duan, H., & Chen, P. (2026) · Functional & Integrative Genomics · doi:10.1007/s10142-026-01844-w · Cited by 2 · see citing works

Applications and Mechanisms of Taohong Siwu Decoction in the Treatment of Ischemic Stroke

Liu, R., Li, Y., Zhang, X., Tang, K., Li, J., Fang, T., Tian, X., & Han, B. (2024) · Pharmacognosy Magazine · doi:10.1177/09731296241235435 · Cited by 2 · see citing works

Unraveling the role of Globularia species in modern medicine based on evidence from photochemistry, traditional uses and biological activities

El-Seedi, H. R., Sabry, A., Abolibda, T. Z., Guo, Z., Nahar, L., Sarker, S. D., Saeed, A., Cheng, G., Karav, S., Efferth, T., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156466 · Cited by 2 · see citing works

[Absorption and pharmacokinetics of radix rehmanniae in rats].

Zhong, J., Tan, Z.-D., Wang, T., Shi, R., & Ma, Y.-M. (2013) · PubMed · Cited by 2 · see citing works

Studies about the bioactive component analysis and an oral glucose tolerance test of Add-Omit-Saenghyeoryunbu-eum(AO-SHU) for confirmation of diabetes therapy

In, J., Im, D.-S., & Kim, W. (2016) · Herbal Formula Science · doi:10.14374/hfs.2016.24.2.80 · Cited by 2 · see citing works

Therapeutic effect of catalpol on type 2 diabetic mice induced by STZ and high-fat diet and its possible mechanism

Xiao, M., Chen, H., Cheng, W., Xu, S., & Ye, Y.-H. (2018) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-018-0685-3 · Cited by 1 · see citing works

Huoxue-Jiangtang decoction ameliorates type 2 diabetes in high-fat diet and streptozotocin-induced rats

Lee, M., Tan, Y., Li, H.-L., Liu, D., & Zhao, H. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1675295 · Cited by 1 · see citing works

Binding of Catalpol to Bovine Serum albumin in vitro Examined by Spectroscopy and Molecular Modeling

Zhu, J., Chen, L., Hu, W., Li, J., & Liu, X. (2016) · Journal of Applied Spectroscopy · doi:10.1007/s10812-016-0365-3 · Cited by 1 · see citing works

Peer Review #2 of "Screening of a natural compound library identifies emodin, a natural compound from Rheum palmatum Linn that inhibits DPP4 (v0.1)"

(2017) · PeerJ · doi:10.7287/peerj.3283v0.1/reviews/2 · Cited by 1 · see citing works

LC/MS/MS and radioisotope method combined for recognizing the affinity between catalpol and OCT2 transporter

Zhang, Z., Liu, C., Si, D., Lu, R., & Yi, X. (2012) · Frontiers of Chemical Science and Engineering · doi:10.1007/s11705-012-1222-4

Assinalamento Completo e Avaliação do Perfil Farmacocinético e Toxicológico do 3-butin-1-il 4,6-di-O-acetil-2,3-didesoxi-α-D-eritro-hex-2-enopiranosídeo

Silva, J. F., de Medeiros, H. I. R., Lima, J. A. D. C., Filho, J. R. D. F., & Freitas, J. C. R. (2020) · Scientia Plena · doi:10.14808/sci.plena.2020.047202

Síntese, assinalamento completo e estudo do perfil farmacocinético, bioativo e de toxicidade do 2-propin-1-il 2,3,4,6-tetra-O-acetil-β-D-glicopiranose

Santos, J. A. M., Santos, C. L. A. A., Filho, J. R. D. F., & Freitas, J. C. R. (2020) · Scientia Plena · doi:10.14808/sci.plena.2020.077201

14. チョウとガにおける環境指標性と環境評価への利用について(日本鱗翅学会第33回大会一般講演要旨)

田中, 蕃. (1986) · 蝶と蛾

Peer Review #1 of "Screening of a natural compound library identifies emodin, a natural compound from Rheum palmatum Linn that inhibits DPP4 (v0.1)"

(2017) · PeerJ · doi:10.7287/peerj.3283v0.1/reviews/1

Peer Review #1 of "Screening of a natural compound library identifies emodin, a natural compound from Rheum palmatum Linn that inhibits DPP4 (v0.2)"

(2017) · PeerJ · doi:10.7287/peerj.3283v0.2/reviews/1

Quantification of catalpol in root of Rehmannia glutinosa varieties 19 collected in Phu Tho province by high-performance liquid chromatography

Pham, T. L. (2024) · Ministry of Science and Technology Vietnam · doi:10.31276/vjst.66(3).20-24

Therapeutic values of Traditional Chinese medicine (TCM) in evolution of Type 1 Diabetes Mellitus with its Microvascular Complications in Adults

Wen, S., Yuan, X., Jiyu, L., & Zhou, L. (2026) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2026.100826

Potential of Rehmanniae Radix for treatment of diabetes mellitus

Tang, D., Sisan, L., Haijing, Z., Ruiqi, Y., Chon-Kit, C., Yitao, W., Zhangfeng, Z., & Chong, C. (2026) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2026.09.003

Phytochemistry and Pharmacological Activities of Rehmannia glutinosa: A Comprehensive Review

Kwak, H., Lee, H., Youn, I., & Seo, E. K. (2026) · Molecules · doi:10.3390/molecules31193435

Plasma Glucose Lowering Mechanisms of Catalpol, an Active Principle from Roots of Rehmannia glutinosa, in Streptozotocin-Induced Diabetic Rats

Shieh, J., Cheng, K., Chung, H.-H., Kerh, Y.-F., Yeh, C., & Cheng, J. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf200069t · Cited by 102 · see citing works

Antidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high-sugar feed

Zhu, H., Wang, Y., Liu, Z., Wang, J., Wan, D., Feng, S., Yang, X. Q., & Wang, T. (2016) · Chinese Medicine · doi:10.1186/s13020-016-0096-7 · Cited by 78 · see citing works

Experimental Study on the Hypoglycemic Activity of Catalpol from Rehmannia glutinosa Libosch.

Zuze, W. (2009) · Lishizhen Medicine and Materia Medica Research · Cited by 4 · see citing works

The Active Ingredient Catalpol in Rehmannia glutinosa Reduces Blood Glucose in Diabetic Rats via the AMPK Pathway

Li, Y., Chen, Q., Sun, H. J., Zhang, J. H., & Liu, X. (2024) · DOAJ (DOAJ: Directory of Open Access Journals)

Hypoglycemic effect of catalpol on high-fat diet/streptozotocin-induced diabetic mice by increasing skeletal muscle mitochondrial biogenesis

Xia, Li, Zhimeng, Xu, Zhenzhou, Jiang, Lixin, Sun, ., Jinzi, Ji, et al. (2014) · 生物化学与生物物理学报：英文版