The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Barbamide, a Chlorinated Metabolite with Molluscicidal Activity from the Caribbean Cyanobacterium Lyngbya majuscula
Abstract
The lipid extract from a Curaçao collection of the marine cyanobacterium Lyngbya majuscula was toxic to the mollusc Biomphalaria glabrata. Subsequent bioassay-guided fractionation of this extract yielded a novel lipopeptide, barbamide, as the active compound (LC100 = 10 micrograms/mL). The structure of barbamide was determined by spectroscopic methods and was found to contain several unique structural features, including a trichloromethyl group and the methyl enol ether of a beta-keto amide.
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Citations
Cites
Gerwick, W. H., Proteau, P. J., Nagle, D. G., Hamel, E., Blokhin, A., & Slate, D. L. (1994) · The Journal of Organic Chemistry · doi:10.1021/jo00085a006 · Cited by 365
Self-citation
Cited by
Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,866
Marine cyanobacteria—a prolific source of natural products
Burja, A. M., Banaigs, B., Abou-Mansour, E., Grant Burgess, J., & Wright, P. C. (2001) · Tetrahedron · doi:10.1016/s0040-4020(01)00931-0 · Cited by 841
Naturally Occurring Organohalogen Compounds
Gribble, G. W. (1998) · Accounts of Chemical Research · doi:10.1021/ar9701777 · Cited by 697
Molecular Networking as a Dereplication Strategy
Yang, J. Y., Sanchez, L. M., Rath, C. M., Liu, X., Boudreau, P. D., Bruns, N., Glukhov, E., Wodtke, A., de Felicio, R., Fenner, A., et al. (2013) · Journal of Natural Products · doi:10.1021/np400413s · Cited by 607
Self-citationMarine natural products as anticancer drugs
Simmons, T. L., Andrianasolo, E., McPhail, K., Flatt, P., & Gerwick, W. H. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.333.4.2 · Cited by 597
Blunt, J. W., Copp, B. R., Hu, W.-P., Munro, M. H. G., Northcote, P. T., & Prinsep, M. R. (2008) · Natural Product Reports · doi:10.1039/b701534h · Cited by 365
Metadata
- Authors
- Orjala, J., & Gerwick, W. H.
- Venue
- Journal of Natural Products
- Publisher
- American Chemical Society (ACS)
- Published
- 1996-01-01
- Volume
- 59
- Issue
- 4
- Pages
- 427-430
- ISSN
- 0163-3864 (ISSN-L)
- 1520-6025
- OpenAlex
- W2067493123
- Cited by
- 186
- References
- 1
- FWCI
- 4.50
- Type
- journal article
- Language
- en
- Open access
- closed
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