The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Fluorescence Imaging of Cellular Glutathione Using a Latent Rhodamine
Abstract
Glutathione is a crucial component of the redox homeostasis of cells, and altered levels have been linked to human pathologies. We constructed a latent fluorophore (RhoSS) that responds to cellular thiols in vitro and in cyto following intracellular reduction by glutathione to yield rhodamine 110. Importantly, RhoSS was demonstrated to respond to changing levels of glutathione in cells. This compound represents a class of rationally designed latent fluorophores with exciting potential for monitoring cellular thiols.
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Citations
Cites
Jones, D. P. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.1865 · Cited by 1,726
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
Dooley, C. T., Dore, T. M., Hanson, G. T., Jackson, W. C., Remington, S. J., & Tsien, R. Y. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312847200 · Cited by 776
Cited by
A new trend in rhodamine-based chemosensors: application of spirolactam ring-opening to sensing ions
Kim, H. N., Lee, M. H., Kim, H. J., Kim, J. S., & Yoon, J. (2008) · Chemical Society Reviews · doi:10.1039/b802497a · Cited by 1,649
Fluorescent and colorimetric probes for detection of thiols
Chen, X., Zhou, Y., Peng, X., & Yoon, J. (2010) · Chemical Society Reviews · doi:10.1039/b925092a · Cited by 1,580
Ratiometric Detection of Mitochondrial Thiols with a Two-Photon Fluorescent Probe
Lim, C. S., Masanta, G., Kim, H. J., Han, J. H., Kim, H. M., & Cho, B. R. (2011) · Journal of the American Chemical Society · doi:10.1021/ja205081s · Cited by 365
Li, H., Fan, J., Wang, J., Tian, M., Du, J., Sun, S., Sun, P., & Peng, X. (2009) · Chemical Communications · doi:10.1039/b907511a · Cited by 339
Thiol Reactive Probes and Chemosensors
Peng, H., Chen, W., Cheng, Y., Hakuna, L., Strongin, R., & Wang, B. (2012) · Sensors · doi:10.3390/s121115907 · Cited by 275
Metadata
- Authors
- Pires, M. M., & Chmielewski, J.
- Venue
- Organic Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-02-08
- Volume
- 10
- Issue
- 5
- Pages
- 837-840
- ISSN
- 1523-7052 (ISSN-L)
- 1523-7060
- OpenAlex
- W1998395915
- Cited by
- 205
- References
- 2
- FWCI
- 6.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pires, M. M., & Chmielewski, J. (2008). Fluorescence Imaging of Cellular Glutathione Using a Latent Rhodamine. Organic Letters. https://doi.org/10.1021/ol702769n
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
