Enantioselective Synthesis and Enantiomeric Amplification of Amino Acids under Prebiotic Conditions

Enantiomeric Excesses in Meteoritic Amino Acids

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Circular Polarization in Star- Formation Regions: Implications for Biomolecular Homochirality

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The origin and amplification of biomolecular chirality

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Thermodynamic control of asymmetric amplification in amino acid catalysis

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Asymmetric photolysis of (RS)-leucine with circularly polarized ultraviolet light

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The Chemistry of Life's Origin:  A Carbonaceous Meteorite Perspective

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A Search for Endogenous Amino Acids in Martian Meteorite ALH84001

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α-Hydroxycarboxylic acids in the Murchison meteorite

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Magnetite in CI Carbonaceous Meteorites: Origin by Aqueous Activity on a Planetesimal Surface

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N,O‐Acetals from Pivalaldehyde and Amino Acids for the α‐Alkylation with Self‐Reproduction of the Center of Chirality. Enolates of 3‐Benzoyl‐2‐(tert‐butyl)‐1,3‐oxazolidin‐5‐ones

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Asymmetric Adsorption of Alanine by Quartz

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The deuterium enrichment of individual amino acids in carbonaceous meteorites: A case for the presolar distribution of biomolecule precursors

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Amplification of enantiomeric concentrations under credible prebiotic conditions

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Isotopic analyses of nitrogenous compounds from the Murchison meteorite: ammonia, amines, amino acids, and polar hydrocarbons

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The carbon isotopic distribution of Murchison amino acids

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Emergence of Solution-Phase Homochirality via Crystal Engineering of Amino Acids

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L ‐Phenylalanine Cyclohexylamide: A simple and convenient auxiliary for the synthesis of optically pure α,α‐disubstituted (R)‐ and (S)‐amino acids

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Copper and zinc abundances in chondritic meteorites

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Asymmetric adsorption of DL-alanine hydrochloride by quartz

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Role of Secondary Structure in the Asymmetric Acylation Reaction Catalyzed by Peptides Based on Chiral Cα-Tetrasubstituted α-Amino Acids

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Syntheses and Properties of Zinc and Calcium Complexes of Valinate and Isovalinate: Metalα-Amino Acidates as Possible Constituents of the Early Earth's Chemical Inventory

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Effect of Molecular Chirality on Racemate Stability: α-Amino Acids with Nonpolar R Groups

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Synthesis of Precursors of the Agalacto (Exo) Fragment of the Quartromicins via an Auxiliary-Controlled Exo-Selective Diels−Alder Reaction

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Partial transfer of enantioselective chiralities from α-methylated amino acids, known to be of meteoritic origin, into normal amino acids

Breslow, R., & Levine, M. S. (2006) · Tetrahedron Letters · doi:10.1016/j.tetlet.2006.01.018 · Cited by 15 · see citing works

The Origin of Biological Homochirality

Blackmond, D. G. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a002147 · Cited by 408 · see citing works

The Search for Chiral Asymmetry as a Potential Biosignature in our Solar System

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Crystalline Architectures as Templates of Relevance to the Origins of Homochirality

Weissbuch, I., & Lahav, M. (2011) · Chemical Reviews · doi:10.1021/cr1002479 · Cited by 284 · see citing works

On the Origin of Single Chirality of Amino Acids and Sugars in Biogenesis

Hein, J. E., & Blackmond, D. G. (2012) · Accounts of Chemical Research · doi:10.1021/ar200316n · Cited by 214 · see citing works

The Origin of Biological Homochirality

Blackmond, D. G. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a032540 · Cited by 188 · see citing works

Possible chemical and physical scenarios towards biological homochirality

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L-amino acids catalyze the formation of an excess of D-glyceraldehyde, and thus of other D sugars, under credible prebiotic conditions

Breslow, R., & Cheng, Z.-L. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001639107 · Cited by 122 · see citing works

On the origin of terrestrial homochirality for nucleosides and amino acids

Breslow, R., & Cheng, Z.-L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904350106 · Cited by 118 · see citing works

Biomimetic Chemistry: Biology as an Inspiration

Breslow, R. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.x800011200 · Cited by 104 · see citing works

Enantioselective Organocatalytic Addition of Oxazolones to 1,1‐Bis(phenylsulfonyl)ethylene: A Convenient Asymmetric Synthesis of Quaternary α‐Amino Acids

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Racemic β-Sheets as Templates of Relevance to the Origin of Homochirality of Peptides: Lessons from Crystal Chemistry

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Molecular Chirality in Meteorites and Interstellar Ices, and the Chirality Experiment on Board the ESA Cometary Rosetta Mission

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Insights into Abiotically-Generated Amino Acid Enantiomeric Excesses Found in Meteorites

Burton, A. S., & Berger, E. L. (2018) · Life · doi:10.3390/life8020014 · Cited by 58 · see citing works

Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis

Wagner, A. J., Zubarev, D. Y., Aspuru-Guzik, A., & Blackmond, D. G. (2017) · ACS Central Science · doi:10.1021/acscentsci.7b00085 · Cited by 52 · see citing works

Stereoselective synthesis of acyclic α,α-disubstituted α-amino acids derivatives from amino acids templates

Cativiela, C., Ordóñez, M., & Viveros‐Ceballos, J. L. (2019) · Tetrahedron · doi:10.1016/j.tet.2019.130875 · Cited by 50 · see citing works

Homochirality and chemical evolution: new vistas and reflections on recent models

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d -Amino acids in molecular evolution in space – Absolute asymmetric photolysis and synthesis of amino acids by circularly polarized light

Sugahara, H., Meinert, C., Nahon, L., Jones, N. C., Hoffmann, S. V., Hamase, K., Takano, Y., & Meierhenrich, U. J. (2018) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2018.01.004 · Cited by 38 · see citing works

A likely possible origin of homochirality in amino acids and sugars on prebiotic earth

Breslow, R. (2011) · Tetrahedron Letters · doi:10.1016/j.tetlet.2010.08.094 · Cited by 35 · see citing works

Imitating Prebiotic Homochirality on Earth

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The origin of homochirality in amino acids and sugars on prebiotic earth

Breslow, R. (2011) · Tetrahedron Letters · doi:10.1016/j.tetlet.2011.06.002 · Cited by 32 · see citing works

Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfonyl)ethene. A simple entry to quaternary α-amino acids

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Oxazolone mediated peptide chain extension and homochirality in aqueous microdroplets

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Gas chromatographic separation of stereoisomers of non-protein amino acids on modified γ-cyclodextrin stationary phase

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Enantioselective synthesis of cyclic quaternary α-amino acid derivatives by chiral phosphoric acid catalysis

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Catalysis of Glyceraldehyde Synthesis by Primary or Secondary Amino Acids Under Prebiotic Conditions as a Function of pH

Breslow, R., Ramalingam, V., & Appayee, C. (2013) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-013-9347-0 · Cited by 23 · see citing works

An Experimental Investigation of the Evolution of Chirality in a Potential Dynamic Peptide System: N -Terminal Epimerization and Degradation into Diketopiperazine

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Synthesis and catalytic properties of diverse chiral polyamines

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Prebiotic access to enantioenriched amino acids via peptide-mediated transamination reactions

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High temperature sublimation of α-amino acids: a realistic prebiotic process leading to large enantiomeric excess

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A Broad Substrate Scope of Aza-Friedel–Crafts Alkylation for the Synthesis of Quaternary α-Amino Esters

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Chiral Amplification of Phosphoramidates of Amines and Amino Acids in Water

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On-line sample stacking of peptides in capillary electrophoresis for the study of prebiotic reactions between α,α-dialkylated amino acids and amino acid N-carboxyanhydrides

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Uncovering the chiral bias of meteoritic isovaline through asymmetric photochemistry

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Molekülchiralität in Meteoriten und interstellarem Eis und das Chiralitätsexperiment an Bord der Kometenmission Rosetta der ESA

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Chiral Amplification of Phosphoramidates of Amines and Amino Acids in Water

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Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine

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Artificial enzymes, cancer chemotherapy, conjugation and nanoelectronics, and prebiotic chemistry

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Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto‐Transferring Reactions

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A Life in Physical Organic Chemistry

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Isoleucine as a possible bridge between exogenous delivery and terrestrial enhancement of homochirality

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Enolate, Azaenolate, and Organolithium Alkylations

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Ronald C.D. Breslow (1931–2017): A career in review

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Theoretical investigation of the relationship between four-carbon d-sugars and five l-amino acids

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Replication Processes—From Autocatalysis to Systems Chemistry

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