The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
How Shall We Use the Proteomics Toolbox for Biomarker Discovery?
Open accessAbstract
Biomarker discovery for clinical purposes is one of the major areas in which proteomics is used. However, despite considerable effort, the successes have been relatively scarce. In this perspective paper, we try to highlight and analyze the main causes for this limited success, and to suggest alternate strategies, which will avoid them, without eluding the foreseeable weak points of these strategies. Two major strategies are analyzed, namely, the switch from body fluids to cell and tissues for the initial biomarker discovery step or, if body fluids must be analyzed, the implementation of highly selective protein selection strategies.
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Antman, E. M., Tanasijevic, M. J., Thompson, B., Schactman, M., McCabe, C. H., Cannon, C. P., Fischer, G. A., Fung, A. Y., Thompson, C., Wybenga, D., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199610313351802 · Cited by 1,749
Cited by
Exosomes in bodily fluids are a highly stable resource of disease biomarkers
Boukouris, S., & Mathivanan, S. (2015) · PROTEOMICS – Clinical Applications · doi:10.1002/prca.201400114 · Cited by 586
Decramer, S., de Peredo, A. G., Breuil, B., Mischak, H., Monsarrat, B., Bascands, J.-L., & Schanstra, J. P. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.r800001-mcp200 · Cited by 450
Liang, K., Liu, F., Fan, J., Sun, D., Liu, C., Lyon, C. J., Bernard, D. W., Li, Y., Yokoi, K., Katz, M. H., et al. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0021 · Cited by 364
Saha, K., Rahimi, M., Yazdani, M., Kim, S. T., Moyano, D. F., Hou, S., Das, R., Mout, R., Rezaee, F., Mahmoudi, M., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b00053 · Cited by 355
Biomarkers in Psychiatry: Concept, Definition, Types and Relevance to the Clinical Reality
García-Gutiérrez, M. S., Navarrete, F., Sala, F., Gasparyan, A., Austrich-Olivares, A., & Manzanares, J. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00432 · Cited by 331
Mischak, H., Coon, J. J., Novak, J., Weissinger, E. M., Schanstra, J. P., & Dominiczak, A. F. (2009) · Mass Spectrometry Reviews · doi:10.1002/mas.20205 · Cited by 193
YKL-40 IDENTIFIED BY PROTEOMIC ANALYSIS AS A BIOMARKER OF SEPSIS
Hattori, N., Oda, S., Sadahiro, T., Nakamura, M., Abe, R., Shinozaki, K., Nomura, F., Tomonaga, T., Matsushita, K., Kodera, Y., et al. (2009) · Shock · doi:10.1097/shk.0b013e31819e2c0c · Cited by 83
Forshed, J., Johansson, H. J., Pernemalm, M., Branca, R. M. M., Sandberg, A., & Lehtiö, J. (2011) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m111.010264 · Cited by 32
Metadata
- Authors
- Lescuyer, P., Hochstrasser, D., & Rabilloud, T.
- Venue
- Journal of Proteome Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-07-27
- Volume
- 6
- Issue
- 9
- Pages
- 3371-3376
- ISSN
- 1535-3893 (ISSN-L)
- 1535-3907
- OpenAlex
- W1973406559
- Cited by
- 161
- References
- 1
- FWCI
- 9.73
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
