Comparative Proteomics of Human Monkeypox and Vaccinia Intracellular Mature and Extracellular Enveloped Virions

Manes, Nathan P.; Estep, Ryan D.; Mottaz, Heather M.; Moore, Ronald J.; Clauss, Therese R. W.; Monroe, Matthew E.; Du, Xiuxia; Adkins, Joshua N.; Wong, Scott W.; Smith, Richard D.

doi:10.1021/pr070432+

Cited by 103Poxvirus research and outbreaksAdvanced Proteomics Techniques and Applicationsvaccines and immunoinformatics approaches

The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.

Comparative Proteomics of Human Monkeypox and Vaccinia Intracellular Mature and Extracellular Enveloped Virions

Open access

Manes, Nathan P., Estep, Ryan D., Mottaz, Heather M., Moore, Ronald J., Clauss, Therese R. W., Monroe, Matthew E., Du, Xiuxia, Adkins, Joshua N., Wong, Scott W., Smith, Richard D.·2008·Journal of Proteome Research

DOI 10.1021/pr070432+PMC PMC2517256

Open this paper in CoChat — free account

Abstract

Orthopoxviruses are among the largest and most complex of the animal viruses. In response to the recent emergence of monkeypox in Africa and the threat of smallpox bioterrorism, two orthopoxviruses with different pathogenic potentials, human monkeypox virus and vaccinia virus, were proteomically compared with the goal of identifying proteins required for pathogenesis. Orthopoxviruses were grown in HeLa cells to two different viral forms (intracellular mature virus and extracellular enveloped virus), purified by sucrose gradient ultracentrifugation, denatured using RapiGest surfactant, and digested with trypsin. Unfractionated samples and strong cation exchange HPLC fractions were analyzed by high-resolution reversed-phase nano-LC-MS/MS, and analyses of the MS/MS spectra using SEQUEST and X! Tandem resulted in the confident identification of hundreds of monkeypox, vaccinia, and copurified host-cell proteins. The unfractionated samples were additionally analyzed by LC-MS using an LTQ-Orbitrap, and the accurate mass and elution time tag approach was used to perform quantitative comparisons. Possible pathophysiological roles of differentially abundant Orthopoxvirus proteins are discussed. Data, processed results, and protocols are available at http://www.proteomicsresource.org/.

Integrity signals

Registry

Crossref · 10.1021/pr070432+

Cites

54 of 54 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Most virion compositional mass spectrometry studies have focused on viruses with high proteomic complexity, including Herpesviridae and Poxviridae.
“For compositional analysis, most studies have focused on viruses with high proteomic complexity, including those in the families Herpesviridae (4–9) and Poxviridae (10–12).”
From The Impact of Mass Spectrometry–Based Proteomics on Fundamental Discoveries in Virology (2014) · cites this paper as [11]

A statistical model for identifying proteins by tandem mass spectrometry.
Nesvizhskii, A., Keller, A., Kolker, E., & Aebersold, R. (2003) · Analytical Chemistry · doi:10.1021/ac0341261 · Cited by 4,902
Large-scale analysis of the yeast proteome by multidimensional protein identification technology
Washburn, M. P., Wolters, D. A., & Yates, J. R. (2001) · Nature Biotechnology · doi:10.1038/85686 · Cited by 4,768
BLAST: at the core of a powerful and diverse set of sequence analysis tools
McGinnis, S., & Madden, T. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh435 · Cited by 2,173
Genesis: cluster analysis of microarray data
Sturn, A., Quackenbush, J., & Trajanoski, Z. (2002) · Bioinformatics · doi:10.1093/bioinformatics/18.1.207 · Cited by 1,761
The ankyrin repeat as molecular architecture for protein recognition
Mosavi, L. K., Cammett, T. J., Desrosiers, D. C., & Peng, Z. (2004) · Protein Science · doi:10.1110/ps.03554604 · Cited by 933
A tale of two clades: monkeypox viruses
Likos, A. M., Sammons, S. A., Olson, V. A., Frace, A. M., Li, Y., Olsen-Rasmussen, M. A., Davidson, W., Galloway, R. L., Khristova, M. L., Reynolds, M. G., et al. (2005) · Journal of General Virology · doi:10.1099/vir.0.81215-0 · Cited by 856
Human monkeypox: an emerging zoonosis
Giulio, D. B. D., & Eckburg, P. B. (2004) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(03)00856-9 · Cited by 826
The International Protein Index: An integrated database for proteomics experiments
Kersey, P. J., Duarte, J., Williams, A., Karavidopoulou, Y., Birney, E., & Apweiler, R. (2004) · PROTEOMICS · doi:10.1002/pmic.200300721 · Cited by 693
The formation and function of extracellular enveloped vaccinia virus
Smith, G. L., Vanderplasschen, A. F. C., & Law, M. (2002) · Journal of General Virology · doi:10.1099/0022-1317-83-12-2915 · Cited by 564
Poxvirus tropism
McFadden, G. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1099 · Cited by 530
A method for reducing the time required to match protein sequences with tandem mass spectra
Craig, R., & Beavis, R. C. (2003) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.1198 · Cited by 502
The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase.
Chang, H. W., Watson, J. C., & Jacobs, B. L. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.11.4825 · Cited by 484
Proteomics by FTICR mass spectrometry: Top down and bottom up
Bogdanov, B., & Smith, R. (2004) · Mass Spectrometry Reviews · doi:10.1002/mas.20015 · Cited by 447
Self-citation
Poxvirus genomes: a phylogenetic analysis
Keller, C. G., Hué, S., Kellam, P., & Smith, G. L. (2004) · Journal of General Virology · doi:10.1099/vir.0.19565-0 · Cited by 403
Human monkeypox and smallpox viruses: genomic comparison
Shchelkunov, S. N., Тотменин, А. В., Babkin, I. V., Safronov, P. F., Riazankina, O. I., Petrov, N. A., Gutorov, V. V., Uvarova, E. A., Mikheev, M. V., Sisler, J. R., et al. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03144-1 · Cited by 394
Analysis of the Monkeypox Virus Genome
Shchelkunov, S. N., Тотменин, А. В., Safronov, P. F., Mikheev, M. V., Gutorov, V. V., Riazankina, O. I., Petrov, N. A., Babkin, I. V., Uvarova, E. A., Sandakhchiev, L. S., et al. (2002) · Virology · doi:10.1006/viro.2002.1446 · Cited by 372
Significance of Extracellular Enveloped Virus in the in vitro and in vivo Dissemination of Vaccinia
Payne, L. G. (1980) · Journal of General Virology · doi:10.1099/0022-1317-50-1-89 · Cited by 345
An evaluation, comparison, and accurate benchmarking of several publicly available MS/MS search algorithms: Sensitivity and specificity analysis
Kapp, E. A., Schütz, F., Connolly, L., Chakel, J. A., Meza, J. E., Miller, C. A., Fenyö, D., Eng, J. K., Adkins, J., Omenn, G. S., et al. (2005) · PROTEOMICS · doi:10.1002/pmic.200500126 · Cited by 344
Self-citation
Probability-Based Evaluation of Peptide and Protein Identifications from Tandem Mass Spectrometry and SEQUEST Analysis: The Human Proteome
Qian, W., Liu, T., Monroe, M. E., Strittmatter, E. F., Jacobs, J., Kangas, L. J., Pétritis, K., Camp, D., & Smith, R. D. (2004) · Journal of Proteome Research · doi:10.1021/pr0498638 · Cited by 317
Self-citation
Advances in proteomics data analysis and display using an accurate mass and time tag approach
Zimmer, J. S. D., Monroe, M. E., Qian, W., & Smith, R. D. (2006) · Mass Spectrometry Reviews · doi:10.1002/mas.20071 · Cited by 303
Self-citation
Vaccinia Virus Proteome: Identification of Proteins in Vaccinia Virus Intracellular Mature Virion Particles
Chung, C.-S., Chen, C.-H., Ho, M.-Y., Huang, C.-Y., Liao, C.-L., & Chang, W. (2006) · Journal of Virology · doi:10.1128/jvi.80.5.2127-2140.2006 · Cited by 253
Cowpox Virus Contains Two Copies of an Early Gene Encoding a Soluble Secreted Form of the Type II TNF Receptor
Hu, F.-Q., Smith, C. A., & Pickup, D. J. (1994) · Virology · doi:10.1006/viro.1994.1539 · Cited by 204
MASIC: A software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC–MS(/MS) features
Monroe, M. E., Shaw, J. L., Daly, D. S., Adkins, J., & Smith, R. D. (2008) · Computational Biology and Chemistry · doi:10.1016/j.compbiolchem.2008.02.006 · Cited by 202
Self-citation
VIPER: an advanced software package to support high-throughput LC-MS peptide identification
Monroe, M. E., Tolić, N., Jaitly, N., Shaw, J. L., Adkins, J., & Smith, R. D. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btm281 · Cited by 189
Self-citation
Fusion of intra- and extracellular forms of vaccinia virus with the cell membrane
Doms, R. W., Blumenthal, R., & Moss, B. A. (1990) · Journal of Virology · doi:10.1128/jvi.64.10.4884-4892.1990 · Cited by 180
Poxvirus Immunomodulatory Strategies: Current Perspectives
Johnston, J. B., & McFadden, G. (2003) · Journal of Virology · doi:10.1128/jvi.77.11.6093-6100.2003 · Cited by 176
Protein composition of the vaccinia virus mature virion
Resch, W., Hixson, K. K., Moore, R. J., Lipton, M. S. W., & Moss, B. (2006) · Virology · doi:10.1016/j.virol.2006.08.025 · Cited by 175
Self-citation
Improved Peptide Elution Time Prediction for Reversed-Phase Liquid Chromatography-MS by Incorporating Peptide Sequence Information
Pétritis, K., Kangas, L. J., Yan, B., Monroe, M. E., Strittmatter, E. F., Qian, W., Adkins, J., Moore, R. J., Xu, Y., Lipton, M. S. W., et al. (2006) · Analytical Chemistry · doi:10.1021/ac060143p · Cited by 171
Self-citation
The exit of Vaccinia virus from infected cells
Smith, G. L., & Law, M. (2004) · Virus Research · doi:10.1016/j.virusres.2004.08.015 · Cited by 169
Robust Algorithm for Alignment of Liquid Chromatography−Mass Spectrometry Analyses in an Accurate Mass and Time Tag Data Analysis Pipeline
Jaitly, N., Monroe, M. E., Petyuk, V., Clauss, T. R., Adkins, J., & Smith, R. D. (2006) · Analytical Chemistry · doi:10.1021/ac052197p · Cited by 157
Self-citation
Zoonotic poxvirus infections in humans
Lewis‐Jones, S. (2004) · Current Opinion in Infectious Diseases · doi:10.1097/00001432-200404000-00003 · Cited by 144
Application of Peptide LC Retention Time Information in a Discriminant Function for Peptide Identification by Tandem Mass Spectrometry
Strittmatter, E. F., Kangas, L. J., Pétritis, K., Mottaz, H. M., Anderson, G., Shen, Y., Jacobs, J., Camp, D., & Smith, R. D. (2004) · Journal of Proteome Research · doi:10.1021/pr049965y · Cited by 143
Self-citation
The US smallpox vaccination program: a review of a large modern era smallpox vaccination implementation program
Poland, G. A., Grabenstein, J. D., & NEFF, J. (2005) · Vaccine · doi:10.1016/j.vaccine.2005.01.012 · Cited by 133
Expected adverse events in a mass smallpox vaccination campaign.
Kemper, A. R., Davis, M. M., & Freed, G. L. (2002) · PubMed · Cited by 131
Assembly of vaccinia virus revisited: de novo membrane synthesis or acquisition from the host?
Sodeik, B., & Krijnse‐Locker, J. (2002) · Trends in Microbiology · doi:10.1016/s0966-842x(01)02256-9 · Cited by 123
Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumour necrosis factor receptors.
Alcam√≠, A., Khanna, A., Paul, N. L. M., & Smith, G. L. (1999) · Journal of General Virology · doi:10.1099/0022-1317-80-4-949 · Cited by 123
Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry
Qian, W., Jacobs, J., Camp, D., Monroe, M. E., Moore, R., Gritsenko, M. A., Calvano, S. E., Lowry, S. F., Xiao, W., Moldawer, L. L., et al. (2005) · PROTEOMICS · doi:10.1002/pmic.200400942 · Cited by 121
Self-citation
Analysis of the Salmonella typhimurium Proteome through Environmental Response toward Infectious Conditions
Adkins, J., Mottaz, H. M., Norbeck, A. D., Gustin, J. K., Rue, J., Clauss, T. R., Purvine, S. O., Rodland, K., Heffron, F., & Smith, R. D. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m600139-mcp200 · Cited by 115
Self-citation
Accurate Mass Measurements in Proteomics
Liu, T., Belov, M. E., Jaitly, N., Qian, W., & Smith, R. D. (2007) · Chemical Reviews · doi:10.1021/cr068288j · Cited by 109
Self-citation
Jenner's Smallpox Vaccine: The Riddle of Vaccinia Virus and Its Origin
Duffy, J. J., & Baxby, D. (1982) · The American Historical Review · doi:10.2307/1857909 · Cited by 108
Pox proteomics: mass spectrometry analysis and identification of Vaccinia virion proteins
Yoder, J. D., Chen, T. S., Gagnier, C. R., Vemulapalli, S., Maier, C. S., & Hruby, D. E. (2006) · Virology Journal · doi:10.1186/1743-422x-3-10 · Cited by 104
Secreted Immunomodulatory Viral Proteins as Novel Biotherapeutics
Lucas, A. R., & McFadden, G. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.8.4765 · Cited by 98
Viral mimicry of the complement system
Bernet, J., Mullick, J., Singh, A. K., & Sahu, A. (2003) · Journal of Biosciences · doi:10.1007/bf02970145 · Cited by 89
PRISM: A data management system for high‐throughput proteomics
Kiebel, G. R., Auberry, K. J., Jaitly, N., Clark, D. A., Monroe, M. E., Peterson, E., Tolić, N., Anderson, G., & Smith, R. D. (2006) · PROTEOMICS · doi:10.1002/pmic.200500500 · Cited by 75
Self-citation
Orthopoxvirus IL-18 Binding Proteins: Affinities and Antagonist Activities
Calderara, S., Xiang, Y., & Moss, B. A. (2001) · Virology · doi:10.1006/viro.2000.0689 · Cited by 73
The Vaccinia Virus A33R Protein Provides a Chaperone Function for Viral Membrane Localization and Tyrosine Phosphorylation of the A36R Protein
Wolffe, E. J., Weisberg, A. S., & Moss, B. A. (2001) · Journal of Virology · doi:10.1128/jvi.75.1.303-310.2001 · Cited by 72
Spatial mapping of protein abundances in the mouse brain by voxelation integrated with high-throughput liquid chromatography–mass spectrometryPreprint
Petyuk, V., Qian, W., Chin, M. H., Wang, H., Livesay, E. A., Monroe, M. E., Adkins, J., Jaitly, N., Anderson, D. J., Camp, D., et al. (2007) · Genome Research · doi:10.1101/gr.5799207 · Cited by 72
Self-citation
Poxvirus Bioinformatics Resource Center: a comprehensive Poxviridae informational and analytical resource
Lefkowitz, E. J. (2004) · Nucleic Acids Research · doi:10.1093/nar/gki110 · Cited by 55
Risks of serious complications and death from smallpox vaccination: A systematic review of the United States experience, 1963–1968
Aragón, T., Ulrich, S., Fernyak, S. E., & Rutherford, G. W. (2003) · BMC Public Health · doi:10.1186/1471-2458-3-26 · Cited by 53
Ankyrin‐like proteins of variola and vaccinia viruses
Shchelkunov, S. N., Blinov, V. M., & Sandakhchiev, L. S. (1993) · FEBS Letters · doi:10.1016/0014-5793(93)80059-4 · Cited by 51
Estimating probabilities of peptide database identifications to LC-FTICR-MS observations
Anderson, K. K., Monroe, M. E., & Daly, D. S. (2006) · Proteome Science · doi:10.1186/1477-5956-4-1 · Cited by 50
Self-citation
Vaccinia Virus Gene B7R Encodes an 18-kDa Protein That is Resident in the Endoplasmic Reticulum and Affects Virus Virulence
Price, N., Tscharke, D. C., Hollinshead, M. S., & Smith, G. L. (2000) · Virology · doi:10.1006/viro.1999.0116 · Cited by 39
Mass Measurement Accuracy in Analyses of Highly Complex Mixtures Based Upon Multidimensional Recalibration
Tolmachev, A. V., Monroe, M. E., Jaitly, N., Petyuk, V., Adkins, J., & Smith, R. D. (2006) · Analytical Chemistry · doi:10.1021/ac0606251 · Cited by 32
Self-citation
Multiple Genetic Differences between the Monkeypox and Variola Viruses
Shchelkunov, S. N., Тотменин, А. В., Safronov, P. F., Gutorov, V. V., Riazankina, O. I., Petrov, N. A., Babkin, I. V., Uvarova, E. A., Mikheev, M. V., Sisler, J. R., et al. (2002) · Doklady Biochemistry and Biophysics · doi:10.1023/a:1016016013042 · Cited by 13

Flagged first, then by citations

Research works printed but not linked: 1

Kemper A. R., 2002, Eff. Clin. Pract., 5, 84

Sorted by citations

Orbitrap mass spectrometry: Instrumentation, ion motion and applications
Perry, R. H., Cooks, R. G., & Noll, R. J. (2008) · Mass Spectrometry Reviews · doi:10.1002/mas.20186 · Cited by 550
Monkeypox virus and insights into its immunomodulatory proteins
Weaver, J. R., & Isaacs, S. N. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00691.x · Cited by 295
Monkeypox: epidemiology, pathogenesis, treatment and prevention
Huang, Y., Li, M., & Wang, W. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01215-4 · Cited by 287
High Resolution Mass Spectrometry
Xian, F., Hendrickson, C. L., & Marshall, A. G. (2012) · Analytical Chemistry · doi:10.1021/ac203191t · Cited by 281
Prevention of monkeypox with vaccines: a rapid review
Poland, G. A., Kennedy, R. B., & Tosh, P. K. (2022) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(22)00574-6 · Cited by 238
Monkeypox: A New Threat?
Kmieć, D., & Kirchhoff, F. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147866 · Cited by 216
Proteomics of the Autographa californica Nucleopolyhedrovirus Budded Virions
Wang, R., Dèng, F., Hou, D., Zhao, Y. B., Guo, L., Wáng, H., & Hú, Z. (2010) · Journal of Virology · doi:10.1128/jvi.00040-10 · Cited by 182
Downstream processing of cell culture-derived virus particles
Wolf, M. W., & Reichl, U. (2011) · Expert Review of Vaccines · doi:10.1586/erv.11.111 · Cited by 131
Deletion of the Monkeypox Virus Inhibitor of Complement Enzymes Locus Impacts the Adaptive Immune Response to Monkeypox Virus in a Nonhuman Primate Model of Infection
Estep, R. D., Messaoudi, I., O’Connor, M. A., Li, H., Sprague, J., Barron, A., Engelmann, F., Yen, B., Powers, M. F., Jones, J. M., et al. (2011) · Journal of Virology · doi:10.1128/jvi.00199-11 · Cited by 112
Self-citation
Preparedness for a monkeypox outbreak
Luo, Q., & Han, J. (2022) · Infectious Medicine · doi:10.1016/j.imj.2022.07.001 · Cited by 84
Poxvirus Proteomics and Virus-Host Protein Interactions
Vliet, K. V., Mohamed, M. R., Zhang, L., Villa, N., Werden, S. J., Liu, J., & McFadden, G. (2009) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00026-09 · Cited by 82
Progress and prospects on vaccine development against monkeypox infection
Saadh, M. J., Ghadimkhani, T., Soltani, N., Abbassioun, A., Pecho, R. D. C., taha, A., Kazem, T. J., Yasamineh, S., & Gholizadeh, O. (2023) · Microbial Pathogenesis · doi:10.1016/j.micpath.2023.106156 · Cited by 74
The Impact of Mass Spectrometry–Based Proteomics on Fundamental Discoveries in Virology
Greco, T. M., Diner, B. A., & Cristea, I. M. (2014) · Annual Review of Virology · doi:10.1146/annurev-virology-031413-085527 · Cited by 67
Proteomic Basis of the Antibody Response to Monkeypox Virus Infection Examined in Cynomolgus Macaques and a Comparison to Human Smallpox Vaccination
Keasey, S. L., Pugh, C. L., Tikhonov, A. P., Chen, G., Schweitzer, B. I., Nalça, A., & Ulrich, R. G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015547 · Cited by 67
Global Proteomic Analysis of Two Tick-Borne Emerging Zoonotic Agents: Anaplasma Phagocytophilum and Ehrlichia Chaffeensis
Lin, M., Kikuchi, T., Brewer, H. M., Norbeck, A. D., & Rikihisa, Y. (2011) · Frontiers in Microbiology · doi:10.3389/fmicb.2011.00024 · Cited by 67
Immunogenic proteins and potential delivery platforms for mpox virus vaccine development: A rapid review
Wang, Y., Yang, K., & Zhou, H. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125515 · Cited by 59
Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review
Anwar, F., Haider, F., Khan, S., Ahmad, I., Ahmed, N., Imran, M., Rashid, S., Ren, Z., Khattak, S., & Ji, X. (2023) · Life · doi:10.3390/life13020522 · Cited by 61
Aging Enhances the Production of Reactive Oxygen Species and Bactericidal Activity in Peritoneal Macrophages by Upregulating Classical Activation Pathways
Smallwood, H. S., López‐Ferrer, D., & Squier, T. C. (2011) · Biochemistry · doi:10.1021/bi2011866 · Cited by 56
The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection
Filone, C. M., Caballero, I. S., Dower, K., Mendillo, M. L., Cowley, G. S., Santagata, S., Rozelle, D., Yen, J. Y., Rubins, K., Hacohen, N., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1003904 · Cited by 54
Monkeypox virus diagnosis and laboratory testing
Nakhaie, M., Arefinia, N., Charostad, J., Bashash, D., Abdolvahab, M. H., & Zarei, M. (2022) · Reviews in Medical Virology · doi:10.1002/rmv.2404 · Cited by 50
Analysis of virion associated host proteins in vesicular stomatitis virus using a proteomics approach
Moerdyk-Schauwecker, M. J., Hwang, S., & Grdzelishvili, V. Z. (2009) · Virology Journal · doi:10.1186/1743-422x-6-166 · Cited by 52
In silico identification of potential inhibitors of vital monkeypox virus proteins from FDA approved drugs
Sahoo, A. K., Augusthian, P. D., Muralitharan, I., Vivek-Ananth, R. P., Kumar, K., Gaurav, K., Ranganathan, G., & Samal, A. (2022) · Molecular Diversity · doi:10.1007/s11030-022-10550-1 · Cited by 48
Investigation of solubilization and digestion methods for microsomal membrane proteome analysis using data‐independent LC‐MS E
Mbeunkui, F., & Goshe, M. B. (2011) · PROTEOMICS · doi:10.1002/pmic.200900698 · Cited by 47
Cowpox Virus Expresses a Novel Ankyrin Repeat NF-κB Inhibitor That Controls Inflammatory Cell Influx into Virus-Infected Tissues and Is Critical for Virus Pathogenesis
Mohamed, M. R., Rahman, M. M., Rice, A. D., Moyer, R. W., Werden, S. J., & McFadden, G. (2009) · Journal of Virology · doi:10.1128/jvi.00861-09 · Cited by 47
Mpox Virus: Its Molecular Evolution and Potential Impact on Viral Epidemiology
Yu, X., Shi, H., & Cheng, G. (2023) · Viruses · doi:10.3390/v15040995 · Cited by 48
Immunoinformatic-based design of immune-boosting multiepitope subunit vaccines against monkeypox virus and validation through molecular dynamics and immune simulation
Suleman, M., Rashid, F., Ali, S., Sher, H., Luo, S., Xie, L., & Xie, Z. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1042997 · Cited by 45
Effect of prior immunisation with smallpox vaccine for protection against human Mpox: A systematic review
Akter, F., Hasan, T. B., Alam, F., Das, A., Afrin, S., Maisha, S., Masud, A. A., & Saif‐Ur‐Rahman, K. (2023) · Reviews in Medical Virology · doi:10.1002/rmv.2444 · Cited by 42
The vaccinia virus A56 protein: a multifunctional transmembrane glycoprotein that anchors two secreted viral proteins
DeHaven, B. C., Gupta, K., & Isaacs, S. N. (2011) · Journal of General Virology · doi:10.1099/vir.0.030460-0 · Cited by 42
Human monkeypox (hMPXV) re‐emergence: Host immunity status and current vaccines landscape
Shafaati, M., & Zandi, M. (2022) · Journal of Medical Virology · doi:10.1002/jmv.28251 · Cited by 41
Mpox: The Reemergence of an Old Disease and Inequities
Thornhill, J. P., Gandhi, M., & Orkin, C. M. (2023) · Annual Review of Medicine · doi:10.1146/annurev-med-080122-030714 · Cited by 39
Monkeypox virus viral chemokine inhibitor (MPV vCCI), a potent inhibitor of rhesus macrophage inflammatory protein-1
Jones, J. M., Messauodi, I., Estep, R. D., Orzechowska, B., & Wong, S. W. (2008) · Cytokine · doi:10.1016/j.cyto.2008.05.016 · Cited by 38
Self-citation
Discovery of Mouse Spleen Signaling Responses to Anthrax using Label-Free Quantitative Phosphoproteomics via Mass Spectrometry
Manes, N. P., Li, D., Zhou, W., Du, X., Reghu, N., Kool, A. C., Choi, D., Bailey, C., Petricoin, E. F., Liotta, L. A., et al. (2010) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m110.000927 · Cited by 36
Self-citation
Comparison of the Cowpox Virus and Vaccinia Virus Mature Virion Proteome: Analysis of the Species- and Strain-Specific Proteome
Doellinger, J., Schaade, L., & Nitsche, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141527 · Cited by 36
Characterization of Macaque Pulmonary Fluid Proteome during Monkeypox Infection
Brown, J. N., Estep, R. D., López‐Ferrer, D., Brewer, H. M., Clauss, T. R., Manes, N. P., O’Connor, M. A., Li, H., Adkins, J., Wong, S. W., et al. (2010) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m110.001875 · Cited by 34
Self-citation
Identification of soybean proteins from a single cell type: The root hair
Brechenmacher, L., Nguyen, T. H., Hixson, K. K., Libault, M., Aldrich, J. T., Paša‐Tolić, L., & Stacey, G. S. (2012) · PROTEOMICS · doi:10.1002/pmic.201200160 · Cited by 32
Quantification of Proteins by Label-Free LC-MS/MS
Levin, Y., & Bahn, S. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-780-8_13 · Cited by 31
Accelerated immune senescence and reduced response to vaccination in ovariectomized female rhesus macaques
Engelmann, F., Barron, A., Urbanski, H. F., Neuringer, M., Kohama, S. G., Park, B. S., & Messaoudi, I. (2010) · AGE · doi:10.1007/s11357-010-9178-0 · Cited by 32
Vaccinia Virus Phospholipase Protein F13 Promotes Rapid Entry of Extracellular Virions into Cells
Bryk, P., Brewer, M. G., & Ward, B. M. (2018) · Journal of Virology · doi:10.1128/jvi.02154-17 · Cited by 31
Recent Advances in Research and Management of Human Monkeypox Virus: An Emerging Global Health Threat
Kumar, P., Chaudhary, B., Yadav, N., Devi, S., Pareek, A., Alla, S., Kajal, F., Nowrouzi‐Kia, B., Chattu, V. K., & Gupta, M. M. (2023) · Viruses · doi:10.3390/v15040937 · Cited by 30
Molecular detection of monkeypox and related viruses: challenges and opportunities
Ghate, S. D., Suravajhala, P., Patil, P., Vangala, R. K., Shetty, P. K., & Rao, R. S. P. (2023) · Virus Genes · doi:10.1007/s11262-023-01975-3 · Cited by 27
Characterization of Strategies for Obtaining Confident Identifications in Bottom-Up Proteomics Measurements Using Hybrid FTMS Instruments
Tolmachev, A. V., Monroe, M. E., Purvine, S. O., Moore, R. J., Jaitly, N., Adkins, J., Anderson, G., & Smith, R. D. (2008) · Analytical Chemistry · doi:10.1021/ac801376g · Cited by 26
Self-citation
A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies
Jiang, L. H., Xu, A., Guan, L., Tang, Y., Chai, G., Feng, J., Wu, Y., Li, M., Zhang, C., Liu, X., et al. (2024) · Exploration · doi:10.1002/exp.20230112 · Cited by 23
Cellular Proteins Associated with the Interior and Exterior of Vesicular Stomatitis Virus Virions
Moerdyk-Schauwecker, M. J., Hwang, S., & Grdzelishvili, V. Z. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104688 · Cited by 22
Systems Integration of Biodefense Omics Data for Analysis of Pathogen-Host Interactions and Identification of Potential Targets
McGarvey, P. B., Huang, H., Mazumder, R., Zhang, J., Chen, Y., Zhang, C., Cammer, S. A., Will, R., Odle, M., Sobral, B., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007162 · Cited by 21
Poxviruses package viral redox proteins in lateral bodies and modulate the host oxidative response
Bidgood, S. R., Samolej, J., Novy, K., Collopy, A., Albrecht, D., Krause, M., Burden, J. J., Wollscheid, B., & Mercer, J. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010614 · Cited by 20
Mass spectrometry detection of monkeypox virus: Comprehensive coverage for ranking the most responsive peptide markers
Lozano, C., Grenga, L., Gallais, F., Miotello, G., Bellanger, L., & Armengaud, J. (2022) · PROTEOMICS · doi:10.1002/pmic.202200253 · Cited by 18
Human Antibody Responses to the Polyclonal Dryvax Vaccine for Smallpox Prevention Can Be Distinguished from Responses to the Monoclonal Replacement Vaccine ACAM2000
Pugh, C. L., Keasey, S. L., Korman, L., Pittman, P. R., & Ulrich, R. G. (2014) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00035-14 · Cited by 18
Vaccinia Virus WR53.5/F14.5 Protein Is a New Component of Intracellular Mature Virus and Is Important for Calcium-Independent Cell Adhesion and Vaccinia Virus Virulence in Mice
Izmailyan, R. A., & Chang, W. (2008) · Journal of Virology · doi:10.1128/jvi.00816-08 · Cited by 17
Protein Primary Structure of the Vaccinia Virion at Increased Resolution
Ngo, T., Mirzakhanyan, Y., Moussatché, N., & Gershon, P. D. (2016) · Journal of Virology · doi:10.1128/jvi.01042-16 · Cited by 18
Challenges in Global Distribution and Equitable Access to Monkeypox Vaccines
Danladi, N. P., Agboola, P., Olaniyi, P., Eze, S. E., Oladapo, O., Obiwulu, D., Obiwulu, D., Adeola, O. A., Olawale, K. O., Adiatu, A. I., et al. (2024) · Viruses · doi:10.3390/v16121815 · Cited by 17
Performance Comparisons of Nano-LC Systems, Electrospray Sources and LC–MS-MS Platforms
Liu, Q., Cobb, J. S., Johnson, J. L., Wang, Q., & Agar, J. N. (2013) · Journal of Chromatographic Science · doi:10.1093/chromsci/bms255 · Cited by 17
Fundamentals and Advances of Orbitrap Mass Spectrometry
Ščigelová, M., & Makarov, A. (2000) · Wiley eBooks · doi:10.1002/9780470027318.a9309 · Cited by 19
Constitutive proteins of lumpy skin disease virion assessed by next-generation proteomics
Schlosser-Perrin, L., Holzmüller, P., Fernandez, B., Miotello, G., Dahmani, N., Neyret, A., Bertagnoli, S., Armengaud, J., & Caufour, P. S. (2023) · Journal of Virology · doi:10.1128/jvi.00723-23 · Cited by 15
Exploring the natural products chemical space to abrogate the F3L-dsRNA interface of monkeypox virus to enhance the immune responses using molecular screening and free energy calculations
Suleman, M., Ahmad, T., shah, K., Albekairi, N. A., Alshammari, A., Khan, A., Wei, D., Yassine, H. M., & Crovella, S. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1328308 · Cited by 15
Kinetics of the humoral and cellular immune response up to 1 year from mpox virus infection
Mazzotta, V., Matusali, G., Cimini, E., Colavita, F., Esvan, R., Notari, S., Micheli, G., Bettini, A., Tartaglia, E., Giacinta, A., et al. (2025) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2025.04.026 · Cited by 15
Virus Removal and Virus Purification
Wickramasighe, S. R., Namila, Fan, R., & Qian, X. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813606-5.00003-8 · Cited by 15
Vaccinia virus F5 is required for normal plaque morphology in multiple cell lines but not replication in culture or virulence in mice
Dobson, B. M., Procter, D. J., Hollett, N. A., Flesch, I. E. A., Newsome, T. P., & Tscharke, D. C. (2014) · Virology · doi:10.1016/j.virol.2014.03.020 · Cited by 12
Exploration of drug repurposing for Mpox outbreaks targeting gene signatures and host-pathogen interactions
İmani, S., Aminnezhad, S., Alikarami, M., Abedi, Z., Mosleh, I. S., Maghsoudloo, M., & Taheri, Z. (2024) · Scientific Reports · doi:10.1038/s41598-024-79897-9 · Cited by 11
Apolipoprotein M, identified as a novel hepatitis C virus (HCV) particle associated protein, contributes to HCV assembly and interacts with E2 protein
Cai, H., Yao, W., Huang, J., Xiao, J., Chen, W., Hu, L., Mai, R., Liang, M., Chen, D., Jiang, N., et al. (2020) · Antiviral Research · doi:10.1016/j.antiviral.2020.104756 · Cited by 11
Monkeypox virus: insights into pathogenesis and laboratory testing methods
Kumar, A., Singh, N. K., Anvikar, A. R., & Misra, G. (2024) · 3 Biotech · doi:10.1007/s13205-024-03920-z · Cited by 10
Enhanced Immune Responses in Mice by Combining the Mpox Virus B6R-Protein and Aluminum Hydroxide-CpG Vaccine Adjuvants
Li, J., Li, X., Dong, J., Wei, J., Guo, X., Wang, G., Xu, M., & Zhao, A. (2024) · Vaccines · doi:10.3390/vaccines12070776 · Cited by 10
Molecular analysis of the 2022 mpox outbreak and antiviral activity of dihydroorotate dehydrogenase inhibitors against orthopoxviruses
Cordsmeier, A., Herrmann, A., Gege, C., Kohlhof, H., Korn, K., & Ensser, A. (2024) · Antiviral Research · doi:10.1016/j.antiviral.2024.106043 · Cited by 10
Proteome analysis of vaccinia virus IHD-W-infected HEK 293 cells with 2-dimensional gel electrophoresis and MALDI-PSD-TOF MS of on solid phase support N-terminally sulfonated peptides
Bartel, S. J., Doellinger, J., Darsow, K. H., Bourquain, D. R., Buchholz, R., Nitsche, A., & Lange, H. A. (2011) · Virology Journal · doi:10.1186/1743-422x-8-380 · Cited by 10
Reverse Engineering Field Isolates of Myxoma Virus Demonstrates that Some Gene Disruptions or Losses of Function Do Not Explain Virulence Changes Observed in the Field
Liu, J., Cattadori, I. M., Sim, D. G., Eden, J., Holmes, E. C., Read, A. F., & Kerr, P. J. (2017) · Journal of Virology · doi:10.1128/jvi.01289-17 · Cited by 10
The Generation and Characterization of Monoclonal Antibodies against the MPXV A29L Protein
Zhu, W., Zhang, M., Zhang, M., Jing, R., Zhou, J., Cao, H., Liu, C., Zhu, H., Ghonaim, A. H., Rouby, S. R., et al. (2024) · Viruses · doi:10.3390/v16081184 · Cited by 9
Forensic proteomics of poxvirus production
Wunschel, D. S., Tulman, E. R., Engelmann, H. E., Clowers, B. H., Geary, S. J., Robinson, A., & Liao, X. (2013) · The Analyst · doi:10.1039/c3an00711a · Cited by 9
Oral Infection, Oral Pathology and Salivary Diagnostics of Mpox Disease: Relevance in Dentistry and OMICs Perspectives
Garcia-Júnior, M. A., Andrade, B. S., Guevara-Vega, M. F., de Melo, I. S., Cunha, T. M., Jardim, A. C. G., & Silva, R. S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814362 · Cited by 8
Screening of potential inhibitors against structural proteins from Monkeypox and related viruses of Poxviridae family via docking and molecular dynamics simulation
Kaur, M., Sharma, A., Kaur, H., Singh, M., Devi, B., Raj, A. R. N., Sood, V., Pandey, A., Gartia, J., Kumar, R., et al. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2259489 · Cited by 8
A Comprehensive Review of the Current Monkeypox Outbreak
Kamal, A., Suppah, M., Saadoun, R., & Yassin, M. A. (2023) · Cureus · doi:10.7759/cureus.34807 · Cited by 6
Characterization of a plant-derived monoclonal antibody targeting extracellular enveloped virions of Monkeypox virus
Melendez, J. A., Sun, H., Bonner, J., & Chen, Q. (2024) · Frontiers in Plant Science · doi:10.3389/fpls.2024.1481452 · Cited by 6
Comprehensive overview of 2022 human monkeypox outbreak and its pathology, prevention, and treatment: A strategy for disease control
Yashavarddhan, M. H., Bohra, D., Rana, R., Tuli, H. S., Ranjan, V., Rana, D. S., & Ganguly, N. K. (2023) · Microbiological Research · doi:10.1016/j.micres.2023.127504 · Cited by 6
Molecular Aspects of the Emergence of Monkeypox Virus Clades
Babkin, I. V., Babkina, I. N., & Викторовна, Т. Н. (2025) · Viruses · doi:10.3390/v17121549 · Cited by 5
Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics
Yan, Y., Sun, Y., Sun, G., Niu, C., Zhao, X., Zhao, M., Liu, T., Zhang, S., Zhai, H., Liu, A., et al. (2026) · MedComm · doi:10.1002/mco2.70525 · Cited by 5
Monkeypox virus protein H3L induces injuries in human and mouse
Chen, S., Huang, G., & Liu, J. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06990-2 · Cited by 5
Critical appraisal of Monkeypox (Mpox) in Africa using scoping and systematic review methods
Anjorin, A. A., Odetokun, I. A., Ashaka, O. S., Fadipe, T. O., MUhammed, A., Sogbanmu, T. O., Nyandwi, J. B., Morakinyo, O. M., Dauda, A. B., Adetona, M. A., et al. (2024) · Proceedings of the Nigerian Academy of Science · doi:10.57046/mjcj2507 · Cited by 5
Protein-Centric Data Integration for Functional Analysis of Comparative Proteomics Data
McGarvey, P. B., Zhang, J., Natale, D. A., Wu, C. H., & Huang, H. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-977-2_20 · Cited by 5
Acrylamide inhibits vaccinia virus through vimentin‐independent anti‐viral granule formation
Wood, J. J., White, I. J., Samolej, J., & Mercer, J. (2021) · Cellular Microbiology · doi:10.1111/cmi.13334 · Cited by 5
EVALUATION OF RAPIGEST EFFICACY FOR THE DIGESTION OF PROTEINS FROM CELL CULTURES AND HEART TISSUE
Pop, C., Mogoșan, C., & Loghin, F. (2014) · Medicine and Pharmacy Reports · doi:10.15386/cjmed-367 · Cited by 4
Emerging and neglected tropical diseases: translational application of proteomics
Denman, B., & Goodman, S. R. (2011) · Experimental Biology and Medicine · doi:10.1258/ebm.2011.011067 · Cited by 4
Comparative Proteomics of two Vibrio anguillarum Serotype O1 Strains with Different Virulence Phenotypes
Zhao, P. H., Huang, J., & Wang, X. (2012) · Current Microbiology · doi:10.1007/s00284-012-0156-x · Cited by 4
Label-free proteomics analysis on the envelope of budded viruses of Bombyx mori nucleopolyhedrovirus harboring differential localized GP64
Hao, B., Li, J., Sun, C., & Huang, J. (2022) · Virus Genes · doi:10.1007/s11262-022-01961-1 · Cited by 3
Probing the proteome of mpox virus for in silico design of a multiepitope vaccine
Danazumi, A. U., Adepoju, O. A., Dibba, L. B. S., Ibrahim, B., Gital, S. I., Joseph, G. I., Chang, G. A., & Balogun, E. O. (2023) · Future Drug Discovery · doi:10.4155/fdd-2023-0013 · Cited by 3
Proteomics for Microbial Forensics
Merkley, E. D. (2019) · ACS symposium series · doi:10.1021/bk-2019-1339.ch009 · Cited by 3
Quantification of Proteins by Label-Free LC-MSE
Savidor, A., & Levin, Y. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-0685-7_15 · Cited by 2
Biological Characteristics and Pathogenesis of Monkeypox Virus: An Overview
Kalaba, M. H., El-Sherbiny, G. M., Sharaf, M. H., & Farghal, E. E. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-57165-7_6 · Cited by 2
Recent information about Mpox disease
Dowran, R., Karimizadeh, Z., Mohebbi, A., Jazayeri, S. M., Taghavi, F. S., & Rasaee, M. J. (2025) · Vacunas · doi:10.1016/j.vacun.2025.500486 · Cited by 1
The Vaccinia Virus A56/Vcp Complex: Mechanism of Formation and Implications for Virulence
DeHaven, B. C. (2011)
EMSL Fiscal Year 2008 Annual Report
Showalter, M. A. (2009) · doi:10.2172/947897
EMSL Science Highlights Report: FY2008, 2nd Quarter
Showalter, M. A. (2008) · doi:10.2172/936764
Mass spectrometric analysis of therapeutic proteins and complex biological samples
Liu, S. (2013) · Digital Repository Service (Northeastern University) · doi:10.17760/d20003083
Application of peptide retention time in proteome research
Shao, C., & Gao, Y. (2010) · Chinese Journal of Chromatography · doi:10.3724/sp.j.1123.2012.00128
Structural and functional analysis of the Vaccinia virus O1 virulence protein
Weeks, A. C. (2017) · The Scholarship East Carolina University's Institutional Repository (East Carolina University)
Test
Anandh, A. (2023) · International Journal of Pharmacometrics and Integrated Biosciences · doi:10.26452/ijpib.v8i1.1493
Looming another global crisis-Monkeypox: Plan of action for third world countries
Varala, R., & Madhavedi, S. (2023) · Asian Journal of Research in Chemistry · doi:10.52711/0974-4150.2023.00035
Exploring Broccoli's Secondary Metabolites as Promising Inhibitors against Monkeypox: In silico ApproachPreprint
Gangwar, U., ., P., & Deep, S. (2024) · Research Square · doi:10.21203/rs.3.rs-3994752/v1
Monkeypox Virus, A Global Public Health Concern and Challenge for Low-income Countries including Pakistan: A Right Time to Nip the Evil in the Bud
Piracha, Z. Z., Ali, H., Rasheed, N. U. H., Saeed, U., Gilani, S. S., Abbasi, U. A., Qasim, K., Noor, E., & Seneen, N. (2023) · International Journal of Clinical Virology · doi:10.29328/journal.ijcv.1001055
Monkeypox (MPOX): Unmasking the Lesser-known Viral Threat
Shah, S., Gupta, R., & Mathur, N. (2024) · Journal of Health Science and Medical Research · doi:10.31584/jhsmr.20241081
mpox (monkeypox) clinical management—a review
Sharma, V., Kushwaha, V., Sheikh, I., Panwar, A., Bose, J. C., Devi, A., Datta, S., & Sharma, A. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-22123-1.00004-1
Recent information about Mpox disease
Dowran, R., Karimizadeh, Z., Mohebbi, A., Jazayeri, S., Taghavi, F. S., & Rasaee, M. J. (2026) · Vacunas (English Edition) · doi:10.1016/j.vacune.2026.500486
Tracking the Trail of Monkeypox: From Origins to Outbreak Control
Jangir, A., Swami, A., Kumari, N. P., Kumar, H., Arya, H., Yadav, N., Kumar, D., & Bhatt, T. K. (2026) · Cell Biochemistry and Function · doi:10.1002/cbf.70239

Comparison of the Cowpox Virus and Vaccinia Virus Mature Virion Proteome: Analysis of the Species- and Strain-Specific Proteome
Doellinger, J., Schaade, L., & Nitsche, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141527 · Cited by 36
RESEARCH ARTICLE Comparison of the Cowpox Virus and Vaccinia Virus Mature Virion Proteome: Analysis of the Species- and Strain-Specific
Doellinger, J., Schaade, L., & Nitsche, A. (2016)
Pox proteomics: mass spectrometry analysis and identification of Vaccinia virion proteins
Yoder, J. D., Chen, T. S., Gagnier, C. R., Vemulapalli, S., Maier, C. S., & Hruby, D. E. (2006) · Virology Journal · doi:10.1186/1743-422x-3-10 · Cited by 104
Proteomic Basis of the Antibody Response to Monkeypox Virus Infection Examined in Cynomolgus Macaques and a Comparison to Human Smallpox Vaccination
Keasey, S. L., Pugh, C. L., Tikhonov, A. P., Chen, G., Schweitzer, B. I., Nalça, A., & Ulrich, R. G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015547 · Cited by 67
Vaccinia Virus Proteome: Identification of Proteins in Vaccinia Virus Intracellular Mature Virion Particles
Chung, C.-S., Chen, C.-H., Ho, M.-Y., Huang, C.-Y., Liao, C.-L., & Chang, W. (2006) · Journal of Virology · doi:10.1128/jvi.80.5.2127-2140.2006 · Cited by 253

Authors: Manes, N. P., Estep, R. D., Mottaz, H. M., Moore, R. J., Clauss, T. R. W., Monroe, M. E., Du, X., Adkins, J. N., Wong, S. W., & Smith, R. D.
Affiliations: Pacific Northwest National Laboratory (US)
Corresponding author: Smith, Richard D.
ORCID: Manes, Nathan P.
Estep, Ryan D.
Moore, Ronald J.
Monroe, Matthew E.
Du, Xiuxia
Adkins, Joshua N.
Wong, Scott W.
Smith, Richard D.
Venue: Journal of Proteome Research
Publisher: American Chemical Society (ACS)
Published: 2008-01-19
Volume: 7
Issue: 3
Pages: 960-968
ISSN: 1535-3893 (ISSN-L)
1535-3907
DOI: 10.1021/pr070432+
PMC: PMC2517256
OpenAlex: W2085841863
Cited by: 103
References: 54
Citations by year: 2026: 6 · 2025: 4 · 2024: 14 · 2023: 17 · 2022: 11 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 7 · 2013: 3 · 2012: 3
FWCI: 3.14
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Journal of Proteome Research (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Allergy and Infectious Diseases (Y1 AI 489401)
National Center for Research Resources (RR18 522, P41RR018522)
Topics: Life Sciences › Immunology and Microbiology › Virology › Poxvirus research and outbreaks
Physical Sciences › Chemistry › Spectroscopy › Advanced Proteomics Techniques and Applications
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › vaccines and immunoinformatics approaches
Keywords: monkeypox virus, vaccinia virus, orthopoxvirus, intracellular mature virus, extracellular enveloped virus, viral proteome, host-virus interaction, pathogenesis, HeLa cells, quantitative proteomics, mass spectrometry
MeSH terms: Chromatography, High Pressure Liquid, Chromatography, Liquid, Electrophoresis, Polyacrylamide Gel, Monkeypox virus, Vaccinia virus, Virion, Proteomics, Tandem Mass Spectrometry

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Comparative Proteomics of Human Monkeypox and Vaccinia Intracellular Mature and Extracellular Enveloped Virions

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks