The DOI matches its Crossref record; 156 of the 156 references it cites were found in a registry or an index.
An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals
Open accessAbstract
The sequence of heterocyclic bases on the interior of the DNA double helix constitutes the genetic code that drives the operation of all living organisms. With this said, it is not surprising that chemical modification of cellular DNA can have profound biological consequences. Therefore, the organic chemistry of DNA damage is fundamentally important to diverse fields including medicinal chemistry, toxicology, and biotechnology. This review is designed to provide a brief overview of the common types of chemical reactions that lead to DNA damage under physiological conditions.
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[57] Sequencing end-labeled DNA with base-specific chemical cleavages
Maxam, A. M., & Gilbert, W. (1980) · Methods in Enzymology · doi:10.1016/s0076-6879(80)65059-9 · Cited by 14,315
The sequence of the human genome
Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
WATSON, J. D., & CRICK, F. H. C. (1953) · Nature · doi:10.1038/171737a0 · Cited by 13,584
Alberts, B., Johnson, A., Lewis, J., Morgan, D., Raff, M., Roberts, K., & Walter, P. (2017) · W.W. Norton eBooks · doi:10.1201/9781315735368 · Cited by 6,365
The DNA damage response: putting checkpoints in perspective
Zhou, B.-B. S., & Elledge, S. J. (2000) · Nature · doi:10.1038/35044005 · Cited by 3,213
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
Shibutani, S., Takeshita, M., & Grollman, A. P. (1991) · Nature · doi:10.1038/349431a0 · Cited by 2,224
Oxidative Nucleobase Modifications Leading to Strand Scission
Burrows, C. J., & Muller, J. G. (1998) · Chemical Reviews · doi:10.1021/cr960421s · Cited by 1,736
The Sequence of the Human Genome
Venter, J. C., Smith, H. O., & Adams, M. D. (2015) · Clinical Chemistry · doi:10.1373/clinchem.2014.237016 · Cited by 1,648
Rate of depurination of native deoxyribonucleic acid
Lindahl, T., & Nyberg, B. (1972) · Biochemistry · doi:10.1021/bi00769a018 · Cited by 1,556
Steenken, S., & Jovanovic, S. V. (1997) · Journal of the American Chemical Society · doi:10.1021/ja962255b · Cited by 1,450
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Minisci reactions: Versatile CH-functionalizations for medicinal chemists
Duncton, M. A. J. (2011) · MedChemComm · doi:10.1039/c1md00134e · Cited by 607
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
Vermeij, W. P., Dollé, M. E. T., Reiling, E., Jaarsma, D., Payan-Gomez, C., Bombardieri, C. R., Wu, H., Roks, A. J. M., Botter, S. M., van der Eerden, B. C., et al. (2016) · Nature · doi:10.1038/nature19329 · Cited by 315
The reactions of dimethyl carbonate and its derivatives
Tundo, P., Musolino, M., & Aricò, F. (2018) · Green Chemistry · doi:10.1039/c7gc01764b · Cited by 264
Coordination of DNA single strand break repair
Abbotts, R., & Wilson, D. M. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.11.039 · Cited by 240
Rios, A. C., & Tor, Y. (2013) · Israel Journal of Chemistry · doi:10.1002/ijch.201300009 · Cited by 98
Sanchez-Contreras, M., Sweetwyne, M. T., Tsantilas, K. A., Whitson, J. A., Campbell, M. D., Kohrn, B. F., Kim, H. J., Hipp, M. J., Fredrickson, J., Nguyen, M. M., et al. (2023) · eLife · doi:10.7554/elife.83395 · Cited by 71
The complicated nature of somatic mtDNA mutations in aging
Sanchez-Contreras, M., & Kennedy, S. R. (2022) · Frontiers in Aging · doi:10.3389/fragi.2021.805126 · Cited by 60
Formation of Abasic Oligomers in Nonenzymatic Polymerization of Canonical Nucleotides
Mungi, C. V., Bapat, N. V., Hongo, Y., & Rajamani, S. (2019) · Life · doi:10.3390/life9030057 · Cited by 17
Sequencing for oxidative DNA damage at single-nucleotide resolution with click-code-seq v2.0
Xiao, S., Fleming, A. M., & Burrows, C. J. (2023) · Chemical Communications · doi:10.1039/d3cc02699j · Cited by 4
Metadata
- Authors
- Gates, K. S.
- Venue
- Chemical Research in Toxicology
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-09-16
- Volume
- 22
- Issue
- 11
- Pages
- 1747-1760
- ISSN
- 0893-228X (ISSN-L)
- 1520-5010
- OpenAlex
- W2028553114
- Cited by
- 484
- References
- 156
- FWCI
- 8.28
- Type
- journal article
- Language
- en
- Open access
- green
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