The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.
Responsiveness to Threat and Incentive in Bipolar Disorder: Relations of the BIS/BAS Scales with Symptoms
Open accessAbstract
Over the past 10 years, theorists have suggested that bipolar disorder symptoms result from increases and decreases in the activity of the Behavioral Activation or Facilitation System (BAS or BFS) and the Behavioral Inhibition System (BIS). These neurobehavioral systems are thought to determine the intensity of affective and behavioral responses to incentives and threats. This study examined cross-sectional and prospective associations of self-reported BIS and BAS with mania and depression in a sample of 59 individuals diagnosed with Bipolar I disorder. Depression was tied to BIS, pointing to the importance of sensitivity to threats in depression. However, links between BIS and depression appeared state-dependent. BAS subscales did not correlate with manic symptoms in a state-dependent manner; however, BAS (total scale and reward responsiveness subscale) predicted relative intensification of manic symptoms over time. Thus, evidence suggests that BAS sensitivity may constitute a vulnerability to mania among persons diagnosed with bipolar disorder. Discussion focuses on the integrative potential of the BIS/BAS constructs for linking psychosocial and biological research on bipolar disorder.
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“Reward motivation is also atypical in individuals with bipolar disorder, as shown by a self-report measure of reward responsivity [269] and in eye-tracking studies of monetary gains and losses [270].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [269]
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Emotion, Emotion Regulation, and Psychopathology: An Affective Science Perspective
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Metadata
- Authors
- Meyer, B., Johnson, S. L., & Winters, R.
- Affiliations
- University of Miami (US)
- Corresponding author
- Meyer, Björn
- Venue
- Journal of Psychopathology and Behavioral Assessment
- Published
- 2001-09
- Volume
- 23
- Issue
- 3
- Pages
- 133-143
- ISSN
- 0164-0305 (ISSN-L)
- 0882-2689
- 1573-3505
- PMC
- PMC3137128
- OpenAlex
- W1555129409
- Cited by
- 326
- References
- 68
- Citations by year
- 2025: 5 · 2024: 3 · 2023: 9 · 2022: 12 · 2021: 16 · 2020: 10 · 2019: 10 · 2018: 17 · 2017: 24 · 2016: 11 · 2015: 23 · 2014: 20 · 2013: 26 · 2012: 20
- FWCI
- 2.79
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Journal of Psychopathology and Behavioral Assessment (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (R29MH055950)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- bipolar disorder, behavioral inhibition system, behavioral activation system, threat sensitivity, incentive sensitivity, mania, depression, reward responsiveness, state dependence, BIS/BAS scales
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