Cited by 76Plant Stress Responses and ToleranceMitochondrial Function and PathologyPhotosynthetic Processes and Mechanisms

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Overexpression of Plant Uncoupling Mitochondrial Protein in Transgenic Tobacco Increases Tolerance to Oxidative Stress

Brandalise, Marcos, Maia, Ivan G., Borecký, Jiri, Vercesi, Aníbal E., Arruda, Paulo·2003·Journal of Bioenergetics and Biomembranes

Abstract

An Arabidopsis thaliana cDNA clone encoding a plant uncoupling mitochondrial protein (AtPUMP1) was overexpressed in transgenic tobacco plants. Analysis of the AtPUMP1 mRNA content in the transgenic lines, determined by Northern blot, revealed variable levels of transgene expression. Antibody probing of Western blots of mitochondrial proteins from three independent transgenic lines showed significant accumulation of AtPUMP1 in this organelle. Overproduction of AtPUMP1 in transgenic tobacco plants led to a significant increase in tolerance to oxidative stress promoted by exogenous hydrogen peroxide as compared to wild-type control plants. These results provide the first biological evidence for a role of PUMP in protection of plant cells against oxidative stress damage.

Overview

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Crossref · 10.1023/a:1024603530043

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39 of 39 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 1

  1. Day, D. A., Neuburger, M., and Douce, R. (1985). Aust. J. Plant Physiol. 12, 219–228.

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Metadata

Authors
Brandalise, M., Maia, I. G., Borecký, J., Vercesi, A. E., & Arruda, P.
Affiliations
  • Universidade Estadual de Campinas (UNICAMP) (BR)
  • Universidade Estadual Paulista (Unesp) (BR)
Corresponding author
Arruda, Paulo
Venue
Journal of Bioenergetics and Biomembranes
Published
2003-06
Volume
35
Issue
3
Pages
203-209
ISSN
  • 0145-479X (ISSN-L)
  • 1573-6881
OpenAlex
W1599293621
Cited by
76
References
39
Citations by year
2026: 1 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 4 · 2021: 1 · 2020: 2 · 2019: 2 · 2017: 3 · 2016: 1 · 2015: 2 · 2014: 5 · 2013: 2 · 2012: 6
FWCI
9.04
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Bioenergetics and Biomembranes (publishedVersion)
  • PubMed (publishedVersion)
  • Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista) (submittedVersion)
  • UNESP Institutional Repository (São Paulo State University) (submittedVersion)
Funders
  • Fundação de Amparo à Pesquisa do Estado de São Paulo
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
Keywords
uncoupling proteins, mitochondrial uncoupling, oxidative stress resistance, hydrogen peroxide, transgenic tobacco, Arabidopsis thaliana, plant stress protection
MeSH terms
Uncoupling Protein 1, Carrier Proteins, Hydrogen Peroxide, Ion Channels, Membrane Proteins, Plant Proteins, RNA, Messenger, Nicotiana, Arabidopsis, Oxidative Stress, Protective Agents, Mitochondrial Proteins, Plants, Genetically Modified

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