The DOI matches its Crossref record; 11 of the 12 references it cites were found in a registry or an index.
Isolation of a petite mutant from a histidine auxotroph of Candida albicans and its characterization
Abstract
Respiration-deficient (petite) mutations have been induced in various yeasts, which are categorized as petite-positive. Candida albicans was classified among the petite-negative yeasts. Since then, a few reports have appeared, describing the isolation of petite mutants in C. albicans. We report in the present study on the isolation of a petite mutant of C. albicans-SAR1. This mutant was isolated from a histidine auxotroph of C. albicans after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine, thus our petite mutant carries a double mutation. SAR1 was characterized morphologically, biochemically and ultrastructurally. The results revealed differences from the wild type in respect to morphological, physiological and biochemical characteristics. Electron microscopy showed that the cells of the petite mutant contain only very few mitochondria that looked 'thread like' without any cristae. The significance of the mutation in the virulence of the mutant vs. that of the wild-type is being assessed.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Other C. albicans petite strains have been described, but most are induced by harsh chemical treatments, and therefore, correlations of specific mitochondrial dysfunctions with azole resistance are more difficult to interpret (15–17).”
From Azole Susceptibility and Transcriptome Profiling in Candida albicans Mitochondrial Electron Transport Chain Complex I Mutants (2013) · cites this paper as [17]
Citations
Cites
Sherman, F., Fink, G. R., & Hicks, J. B. (1979) · Cold Spring Harbor Laboratory eBooks · Cited by 7,430
Chemical Mutagens. Principles and Methods for Their Detection.
(1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-80-3-439_4 · Cited by 1,456
Lee, K. L., BUCKLEY, H. R., & Campbell, C. C. (1975) · Medical Mycology · doi:10.1080/00362177585190271 · Cited by 791
Induction of petite mutation and inhibition of synthesis of respiratory enzymes in various yeasts
Bulder, C. J. E. A. (1964) · Antonie van Leeuwenhoek · doi:10.1007/bf02046695 · Cited by 162
ADVANCES IN THE STUDY OF RESPIRATION-DEFICIENT (RD) MUTATION IN YEAST AND OTHER MICROORGANISMS
Nagai, S., Yanagishima, N., & Nagai, H. (1961) · Bacteriological Reviews · doi:10.1128/br.25.4.404-426.1961 · Cited by 107
Ferguson, L. R., & von Borstel, R. C. (1992) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(92)90042-z · Cited by 93
Lethality of the petite mutation in petite negative yeasts
Bulder, C. J. E. A. (1964) · Antonie van Leeuwenhoek · doi:10.1007/bf02046758 · Cited by 92
DIAGNOSTIC COLOR DIFFERENTIATION PLATES FOR HEREDITARY RESPIRATION DEFICIENCY IN YEAST
Nagai, S. (1963) · Journal of Bacteriology · doi:10.1128/jb.86.2.299-302.1963 · Cited by 50
Induction of petite mutation with acriflavine and elevated temperature inCandida albicans
Aoki, S., & Ito‐Kuwa, S. (1987) · Medical Mycology · doi:10.1080/02681218780000611 · Cited by 36
Selection and characterization of acriflavine-induced mutants of Candida albicans
Watkins, P. D., Brandt, P. M., & McClary, D. O. (1974) · Antonie van Leeuwenhoek · doi:10.1007/bf00394562 · Cited by 20
Cited by
Sorted by citations
Sanglard, D., Ischer, F., & Bille, J. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.4.1174-1183.2001 · Cited by 247
Multidrug Resistance in Yeast Candida
Prasad, R., & Kapoor, K. (2004) · International review of cytology · doi:10.1016/s0074-7696(04)42005-1 · Cited by 185
The Petite Mutation in Yeasts: 50 Years On
Chen, X. J., & Clark-Walker, G. D. (1999) · International review of cytology · doi:10.1016/s0074-7696(08)62397-9 · Cited by 171
Sun, N., Fonzi, W., Chen, H., She, X., Zhang, L., Zhang, L., & Calderone, R. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01520-12 · Cited by 94
Gyurko, C., Lendenmann, U., Troxler, R. F., & Oppenheim, F. G. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.2.348-354.2000 · Cited by 92
Metadata
- Authors
- Roth-Ben Arie, Z., Altboum, Z., Berdicevsky, I., & Segal, E.
- Affiliations
- Israel Institute for Biological Research (IL)
- Technion – Israel Institute of Technology (IL)
- Tel Aviv University (IL)
- ORCID
- Segal, E.
- Venue
- Mycopathologia
- Published
- 1998-03
- Volume
- 141
- Issue
- 3
- Pages
- 127-135
- ISSN
- 0301-486X (ISSN-L)
- 1573-0832
- OpenAlex
- W1515397945
- Cited by
- 11
- References
- 12
- Citations by year
- 2012: 1
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Mycopathologia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Keywords
- petite mutants, Candida albicans, histidine auxotrophs, N-methyl-N'-nitro-N-nitrosoguanidine mutagenesis, double mutations, mitochondrial ultrastructure, mitochondrial cristae, yeast morphology, yeast physiology, virulence
- MeSH terms
- Candida albicans, Cloning, Molecular, Methylnitronitrosoguanidine, Microscopy, Electron, Mutagens, Mycology, Mutagenesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Isolation of a petite mutant from a histidine auxotroph of Candida albicans and its characterization. https://app.cochat.ai/papers/10.1023/a:1006988119891
- The paper
- Roth-Ben Arie, Z., Altboum, Z., Berdicevsky, I., & Segal, E. (1998). Isolation of a petite mutant from a histidine auxotroph of Candida albicans and its characterization. Mycopathologia. https://doi.org/10.1023/a%3A1006988119891
