The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Stress and Preterm Birth: Neuroendocrine, Immune/Inflammatory, and Vascular Mechanisms
Abstract
A growing literature suggests that maternal psychological and social stress is a significant and independent risk factor for a range of adverse reproductive outcomes including preterm birth. Several issues remain to be addressed about stress and vulnerability to stress during pregnancy. Of these, perhaps one of the most important questions relates to biologic plausibility. Parturition, the process that results in birth, is a biological phenomenon. Very little empirical research to date, however, has examined the role of biological processes, if any, as mediators of the relationship between stress and preterm birth. In this paper we discuss the maternal, placental, and fetal neuroendocrine, immune/inflammatory, and vascular processes that may bridge the experience of social adversity before and during pregnancy and the biological outcome of preterm birth.
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“After the completion of the research reported here, Wadhwa and colleagues (2001) described physiological mechanisms by which hormones released during episodes of acute stress and chronic strain can initiate early labor.”
From Resistance and Resilience: The Sojourner Syndrome and the Social Context of Reproduction in Cenral Harlem (2005) · cites this paper as Wadhwa et al. 2001
Citations
Cites
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Research works printed but not linked: 4
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Cited by
Sorted by citations
Epidemiology and causes of preterm birth
Goldenberg, R. L., Culhane, J. F., Iams, J. D., & Romero, R. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60074-4 · Cited by 7,801
Self-citation“Weathering” and Age Patterns of Allostatic Load Scores Among Blacks and Whites in the United States
Geronimus, A. T., Hicken, M., Keene, D., & Bound, J. (2006) · American Journal of Public Health · doi:10.2105/ajph.2004.060749 · Cited by 2,525
The preterm parturition syndrome
Romero, R., Espinoza, J., Kusanovic, J., Gotsch, F., Hassan, S., Erez, O., Chaiworapongsa, T., & Mazor, M. (2006) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2006.01120.x · Cited by 1,419
Health Disparities Beginning in Childhood: A Life-Course Perspective
Braveman, P., & Barclay, C. (2009) · Pediatrics · doi:10.1542/peds.2009-1100d · Cited by 653
Intergenerational Transmission of Stress in Humans
Bowers, M. E., & Yehuda, R. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.247 · Cited by 596
Metadata
- Authors
- Wadhwa, P. D., Culhane, J. F., Rauh, V., & Barve, S. S.
- Affiliations
- University of California, Irvine (US)
- Thomas Jefferson University (US)
- Columbia University (US)
- University of Louisville (US)
- Corresponding author
- Wadhwa, Pathik D.
- Venue
- Maternal and Child Health Journal
- Published
- 2001-06
- Volume
- 5
- Issue
- 2
- Pages
- 119-125
- ISSN
- 1092-7875 (ISSN-L)
- 1573-6628
- OpenAlex
- W1578099808
- Cited by
- 336
- References
- 59
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 10 · 2023: 8 · 2022: 8 · 2021: 14 · 2020: 62 · 2019: 15 · 2018: 13 · 2017: 11 · 2016: 13 · 2015: 16 · 2014: 13 · 2013: 9 · 2012: 19
- FWCI
- 4.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Maternal and Child Health Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- Centers for Disease Control and Prevention (TS31215/15)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD028413, R29HD033506, HD-28413, HD 33506)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Preterm Birth and Chorioamnionitis
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- maternal stress, preterm birth, neuroendocrine mechanisms, vascular mechanisms, placenta, fetal development, social adversity, childbirth, biological plausibility, adverse reproductive outcomes
- MeSH terms
- Cardiovascular Diseases, Female, Humans, Immune System, Infant, Newborn, Infant, Premature, Inflammation, Obstetric Labor, Premature, Neurosecretory Systems, Pregnancy, Stress, Physiological
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