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Cited by 118Glycosylation and Glycoproteins ResearchAllergic Rhinitis and SensitizationFood Allergy and Anaphylaxis Research

The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.

N- and O-linked oligosaccharides of allergenic glycoproteins

Fötisch, Kay, Vieths*, Stefan·2001·Glycoconjugate Journal
DOI 10.1023/a:1014860030380
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Abstract

Cross-linking of cell-bound IgE on mast cells or basophils by polyvalent antigens causes the release of histamine and other mediators of the allergic response which then lead to the development of allergic symptoms. In this event not only peptide epitopes, but also carbohydrates can act as cross-linking elements. Since peptide epitopes of allergens are subject of most published studies, this review is focused on glycosidic epitopes. The current knowledge of the structures and possible epitopes of oligosaccharides linked to allergenic glycoproteins is briefly reviewed, showing that complex plant N-glycans containing alpha1,3 fucose and beta1,2 xylose are most frequently involved in the structures of IgE epitopes. In own studies a prevalence of up to 29% anti-glycan IgE was determined among pollen-allergic patients. The clinical relevance of these carbohydrate specific IgE antibodies is still a matter of controversial discussions.

Overview

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Registry

Crossref · 10.1023/a:1014860030380

Cites

130 of 130 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 8

  1. Alisi C, Afferni C, Iacovacci P, Barletta B, Tinghino R, Butteroni C, Puggioni EMR, Wilson IBH, Federico R, Schinina E, Mari A, Di Felice G, Pini C, Rapid isolation, characterisation and glycan analysis of Cup a 1, the major allergen from Arizona cupress (Cupressus arizonica) pollen, Allergy 56, 978–984 (2001).
  2. Wicklein D, Moll H, Kolarich D, Altmann F, Lindner B, Becker W-M, Petersen A, Haben Kohlenhydratstrukturen einen Einflub auf die Allergenität?, Allergo J 10, 42 (2001).
  3. Wan G-H, Li C-S, Guo S-P, Rylander R, Lin R-H, An airbone mold-derived product, b-1,3-D-glucan, potentiates airway allergic responses, Eur J Immunol 29, 2491–7 (1999). · DOI
  4. Barnes C, Pacheco F, Portnoy J, Carbohydrate and protein contribution to Alternaria allergen activity, J Allergy Clin Immunol 85, 169 (1990).
  5. Petersen A, Becker W-M, Schlaak M, Posttranslationelle Modifizierungen und ihr Einfluß auf die Allergenitaet untersucht am Majorallergen PhI p 1 des Lieschgrases, FOCUS MUL 12, 221–8(1995).
  6. Jankiewicz A, Aulepp H, Altmann F, Fötisch K, Vieths S, Serological investigation of 30 celery-allergic patients with particular consideration of the thermal stability of IgE-binding celery allergens, Allergo J 7, 87–95 (1998).
  7. Wensing M, Akkerdaas J, Stapel S, Bast EJE, Bruijnzeel-Koomen CAF, Aalberse RC, van Ree R, Knulst AC, Skin tests and RASTwith rBet v 1, rBet v 2 and crossreactive carbohydrate determinants (CCDs). Is it possible to reveal individual crossreactivity patterns?, Allergy 56 Suppl 68, 86 (2001).
  8. van Ree R, Akkerdaas JH, Villalba M, Rodriguez R, Koppelman S, Aalberse RC, Faye L, Lerouge P, IgE binding N-glycans: structural and immunological characterization, Allergy 43, 30 (1998).

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Metadata

Authors
Fötisch, K., & Vieths*, S.
Affiliations
Paul Ehrlich Institut (DE)
Venue
Glycoconjugate Journal
Publisher
Springer Science and Business Media LLC
Published
2001-05
Volume
18
Issue
5
Pages
373-390
ISSN
  • 0282-0080 (ISSN-L)
  • 1573-4986
DOI
10.1023/a:1014860030380
OpenAlex
W156274875
Cited by
118
References
130
Citations by year
2026: 1 · 2025: 3 · 2024: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 10 · 2014: 7 · 2013: 5 · 2012: 5
FWCI
0.42
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Glycoconjugate Journal (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Glycosylation and Glycoproteins Research
  • Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
  • Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
Keywords
N-glycans, O-linked oligosaccharides, IgE epitopes, allergic rhinitis, allergic reactions
MeSH terms
Allergens, Animals, Epitopes, Carbohydrate Conformation, Carbohydrate Sequence, Glycoproteins, Humans, Immunoglobulin E, Models, Molecular, Molecular Sequence Data, Oligosaccharides, Protein Conformation

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.