Indirect Evidence that Drug Brain Targeting Using Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles Is Related to Toxicity

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

D'AMOUR, F. E., & Smith, D. L. (1941) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)03823-6 · Cited by 3,238

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

DAVISON, A. N. (1989) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.52.8.1021-a · Cited by 949

Brain drug delivery of small molecules using immunoliposomes

Huwyler, J., Wu, D., & Pardridge, W. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.14164 · Cited by 660

An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro

Dehouck, M., Méresse, S., Delorme, P., Fruchart, J., & Cecchelli, R. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb01236.x · Cited by 548

Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)

Kreuter, J., Alyautdin, R. N., Kharkevich, D. A., & Aa, I. (1995) · Brain Research · doi:10.1016/0006-8993(95)00023-j · Cited by 538

Polycyanoacrylate nanocapsules as potential lysosomotropic carriers: preparation, morphological and sorptive properties

Couvreur, P., Kante, B., Roland, M., Guiot, P., Bauduin, P., & Speiser, P. P. (1979) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1979.tb13510.x · Cited by 453

Drug delivery to the central nervous system: A review

Tamargo, R. J., & Brem, H. (1992) · Neurosurgery Quarterly · Cited by 369

Delivery of Loperamide Across the Blood-Brain Barrier with Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles

Alyautdin, R. N., Petrov, V. E., Langer, K., Berthold, A., Kharkevich, D. A., & Kreuter, J. (1997) · Pharmaceutical Research · doi:10.1023/a:1012098005098 · Cited by 352

Pharmacokinetics and distribution of a biodegradable drug-carrier

Grislain, L., Couvreur, P., Lenaerts, V., Roland, M., Campeneere, D. D.-D., & Speiser, P. P. (1983) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(83)90166-7 · Cited by 305

Molecular sieving characteristics of the cultured endothelial monolayer

Siflinger-Birnboim, A., Vecchio, P. J. D., Cooper, J. A., Blumenstock, F. A., Shepard, J. M., & Malik, A. B. (1987) · Journal of Cellular Physiology · doi:10.1002/jcp.1041320115 · Cited by 256

Tissue distribution of borneol-modified ganciclovir-loaded solid lipid nanoparticles in mice after intravenous administration

Ren, J., Zou, M., Gao, P., Wang, Y., & Cheng, G. (2012) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2012.10.018 · Cited by 56

Neuropharmacokinetic evaluation of methotrexate-loaded chitosan nanogels

Azadi, A., Rouini, M. R., & Hamidi, M. (2015) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2015.05.001 · Cited by 55

Aclarubicin‐loaded cationic albumin‐conjugated pegylated nanoparticle for glioma chemotherapy in rats

Lü, W., Wan, J., Zhang, Q., She, Z., & Jiang, X. (2006) · International Journal of Cancer · doi:10.1002/ijc.22296 · Cited by 54

Supramolecular devices to improve the treatment of brain diseases

Paolino, D., Cosco, D., Molinaro, R., Celia, C., & Fresta, M. (2011) · Drug Discovery Today · doi:10.1016/j.drudis.2011.02.006 · Cited by 53

Brain transport of neurotoxin‐I with PLA nanoparticles through intranasal administration in rats: a microdialysis study

Cheng, Q., Feng, J., Chen, J., Zhu, X., & Li, F. (2008) · Biopharmaceutics & Drug Disposition · doi:10.1002/bdd.621 · Cited by 53

Nanoparticles as Blood–Brain Barrier Permeable CNS Targeted Drug Delivery Systems

Grabrucker, A. M., Chhabra, R., Belletti, D., Forni, F., Vandelli, M. A., Ruozi, B., & Tosi, G. (2013) · Topics in Medicinal Chemistry · doi:10.1007/7355_2013_22 · Cited by 53

Comparison of nanosuspensions and hydroxypropyl-β-cyclodextrin complex of melarsoprol: Pharmacokinetics and tissue distribution in mice

Zirar, S. B., Astier, A., Muchow, M., & Gibaud, S. (2008) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2008.05.012 · Cited by 50

Amphiphilic HPMA–LMA copolymers increase the transport of Rhodamine 123 across a BBB model without harming its barrier integrity

Hemmelmann, M., Metz, V. V., Koynov, K., Blank, K. G., Postina, R., & Zentel, R. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.08.034 · Cited by 48

Nanoformulations for Drug Delivery: Safety, Toxicity, and Efficacy

Lopalco, A., & Denora, N. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7899-1_17 · Cited by 45

Bispecific Antibody Conjugated Manganese-Based Magnetic Engineered Iron Oxide for Imaging of HER2/neu- and EGFR-Expressing Tumors

Wu, S.-C., Chen, Y.-J., Wang, H.-C., Chou, M.-Y., Chang, T., Yuan, S. F., Chen, C.-Y., Hou, M., Hsu, J. T.-A., & Wang, Y. (2015) · Theranostics · doi:10.7150/thno.13069 · Cited by 44

Targeted Drug Delivery Across the Blood Brain Barrier in Alzheimer’s Disease

Rocha, S. (2013) · Current Pharmaceutical Design · doi:10.2174/13816128113199990613 · Cited by 42

A Promising Approach: Magnetic Nanosystems for Alzheimer’s Disease Theranostics

Chaparro, C. I. P., Simões, B. T., Borges, J. P., Castanho, M. A. R. B., Soares, P. I. P., & Neves, V. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15092316 · Cited by 40

Solid lipid nanoparticles in cancer therapy.

Mathur, V., Satrawala, Y., Rajput, M. S., Kumar, P., Shrivastava, P., & Vishvkarma, A. (2010) · International Journal of Drug Delivery · doi:10.5138/ijdd.2010.0975.0215.02029 · Cited by 40

Improvement of cationic albumin conjugated pegylated nanoparticles holding NC-1900, a vasopressin fragment analog, in memory deficits induced by scopolamine in mice

XIE, Y., LU, W., & JIANG, X. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.06.001 · Cited by 40

Potential of polymeric nanoparticles in AIDS treatment and prevention

Khalil, N. M., Carraro, E., Cótica, L. F., & Mainardes, R. M. (2010) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2011.543673 · Cited by 40

Double-stranded RNA (dsRNA) technology to control forest insect pests and fungal pathogens: challenges and opportunities

Singewar, K., & Fladung, M. (2023) · Functional & Integrative Genomics · doi:10.1007/s10142-023-01107-y · Cited by 37

Strategies to overcome the barrier: use of nanoparticles as carriers and modulators of barrier properties

Rempe, R. G., Cramer, S., Qiao, R., & Galla, H. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1819-7 · Cited by 38

Colloidal systems for CNS drug delivery

Costantino, L., Tosi, G., Ruozi, B., Bondioli, L., Vandelli, M. A., & Forni, F. (2009) · Progress in brain research · doi:10.1016/s0079-6123(08)80003-9 · Cited by 35

Crossing the Blood-Brain Barrier: A Review on Drug Delivery Strategies for Treatment of the Central Nervous System Diseases

Mansor, N. I., Nordin, N., Mohamed, F., Ling, K., Rosli, R., & Hassan, Z. (2019) · Current Drug Delivery · doi:10.2174/1567201816666190828153017 · Cited by 34

High glycolic poly (DL lactic co glycolic acid) nanoparticles for controlled release of meropenem

Venkatesan, N., Venkatachalam, G., Chittaranjan, S. B., & Doble, M. (2013) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2013.02.004 · Cited by 34

Development of a chitosan‐based nanoparticle formulation for delivery of a hydrophilic hexapeptide, dalargin

Chen, Y., Siddalingappa, B., Chan, P. H. H., & Benson, H. A. (2008) · Biopolymers · doi:10.1002/bip.21055 · Cited by 34

Role of Nanotechnology for Enzyme Replacement Therapy in Lysosomal Diseases. A Focus on Gaucher’s Disease

Martín‐Banderas, L., Holgado, M. A., Durán‐Lobato, M., Infante, J. J., Álvarez‐Fuentes, J., & Arévalo, M. F. (2016) · Current Medicinal Chemistry · doi:10.2174/0929867323666160210130608 · Cited by 33

Effect of formulation factors on incorporation of the hydrophilic peptide dalargin into PLGA and mPEG‐PLGA nanoparticles

Chen, Y., Wang, F., & Benson, H. A. (2008) · Biopolymers · doi:10.1002/bip.21013 · Cited by 32

The role of peptides in blood‐brain barrier nanotechnology

Teixidò, M., & Giralt, E. (2007) · Journal of Peptide Science · doi:10.1002/psc.983 · Cited by 32

Nanotechnology in medical applications: possible risks for human health

de Jong, W., Roszek, B., & Re, G. (2005) · Rivm Repository (Netherlands National Institute for Public Health and the Environment) · Cited by 31

Paclitaxel-loaded cholesterol-conjugated polyoxyethylene sorbitol oleate polymeric micelles for glioblastoma therapy across the blood–brain barrier

Li, C., Li, S., Tu, T., Qi, X., Xiong, Y., Du, S., Shen, Y., Tu, J., & Sun, C. (2015) · Polymer Chemistry · doi:10.1039/c4py01422g · Cited by 30

Entrapment of Bioactive Molecules in Poly (Alkylcyanoacrylate) Nanoparticles

Krauel, K., Pitaksuteepong, T., Davies, N. M., & Rades, T. (2004) · American Journal of Drug Delivery · doi:10.2165/00137696-200402040-00005 · Cited by 30

Nanoparticles influence pathophysiology of spinal cord injury and repair

Sharma, H. S., Muresanu, D. F., Sharma, A., Patnaik, R., & Lafuente, J. V. (2009) · Progress in brain research · doi:10.1016/s0079-6123(08)80009-x · Cited by 29

Optimizing the Design of Blood–Brain Barrier-Penetrating Polymer-Lipid-Hybrid Nanoparticles for Delivering Anticancer Drugs to Glioblastoma

Ahmed, T., Liu, F.-C. F., He, C., Abbasi, A. Z., Cai, P., Rauth, A. M., Henderson, J. T., & Wu, X. Y. (2021) · Pharmaceutical Research · doi:10.1007/s11095-021-03122-9 · Cited by 28

Peptide Pills for Brain diseases? Reality and Future Perspectives

Serrano, D. R., & Lalatsa, A. (2013) · Therapeutic Delivery · doi:10.4155/tde.13.5 · Cited by 27

Physicochemical properties of engineered nanomaterials that influence their nervous system distribution and effects

Yokel, R. A. (2016) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2016.05.007 · Cited by 27

Nanoparticles for neuroimaging

Re, F., Moresco, R. M., & Masserini, M. (2012) · Journal of Physics D Applied Physics · doi:10.1088/0022-3727/45/7/073001 · Cited by 26

Experimental therapies

Hulou, M. M., Cho, C., Chiocca, E. A., & Bjerkvig, R. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-802997-8.00011-6 · Cited by 24

An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood–brain barrier uptake

Bode, G. H., Coué, G. M. J. P. C., Freese, C., Pickl, K. E., Sánchez-Purrà, M., Albaiges, B., Borrós, S., van Winden, E. C. A., Tziveleka, L., Sideratou, Z., et al. (2016) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2016.11.009 · Cited by 24

Targeted nano-drug delivery system for glioblastoma therapy: In vitro and in vivo study

Hassanzadeganroudsari, M., Soltani, M., Heydarinasab, A., Apostolopoulos, V., Akbarzadehkhiyavi, A., & Nurgali, K. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.102039 · Cited by 22

Design of amphiphilic PCL-PEG-PCL block copolymers as vehicles of Ginkgolide B and their brain-targeting studies

Yan, X., Shi, Y., Qing-feng, J., Ping, G.-F., & Deng, Z. (2017) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2017.1332470 · Cited by 22

Preparation and Characterization of Methylene blue Nanoparticles for Alzheimer’s Disease and Other Tauopathies

Jinwal, U. K., Groshev, A., Zhang, J., Grover, A., & Sutariya, V. B. (2013) · Current Drug Delivery · doi:10.2174/1567201810666131113102037 · Cited by 22

Nanotheranostics revolutionizing neurodegenerative diseases: From precision diagnosis to targeted therapies

Joshi, R., Missong, H., Mishra, J., Kaur, S., Saini, S., Kandimalla, R. J. L., Reddy, P. H., Babu, A. M., Bhatti, G. K., & Bhatti, J. S. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.105067 · Cited by 23

Polymer Nanomaterials for Drug Delivery Across the Blood Brain Barrier

Kabanov, A. V., & Batrakova, E. V. (2016) · Springer eBooks · doi:10.1007/978-3-319-44022-4_50 · Cited by 21

Biologically-Derived Nanomaterials for Targeted Therapeutic Delivery to the Brain

Curley, S. M., & Cady, N. C. (2018) · Science Progress · doi:10.3184/003685018x15306123582346 · Cited by 26

Polymer Nanoparticles as Smart Carriers for the Enhanced Release of Therapeutic Agents to the CNS

Gagliardi, M., & Borri, C. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666161027111542 · Cited by 18

Drug Delivery to the CNS and Polymeric Nanoparticulate Carriers

Costantino, L. (2010) · Future Medicinal Chemistry · doi:10.4155/fmc.10.249 · Cited by 18

Nanotechnology and Its Drug Delivery Applications

Bhatia, S. (2016) · Springer eBooks · doi:10.1007/978-3-319-41129-3_1 · Cited by 17

Blood-brain barrier co-culture models to study nanoparticle penetration: focus on co-culture systems

Veszelka, S., Bocsik, A., Walter, F. R., Hantosi, D., & Deli, M. A. (2015) · Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) · Cited by 16

Do Surface Defects and Modification Determine the Observed Toxicity of Carbon Nanotubes?

Senanayake, V. K., Juurlink, B. H. J., Zhang, W., Zhan, E., Wilson, L. D., Kwon, J., Yang, J., Lim, Z. L., Brunet, S. M. K., Schatte, G., et al. (2008) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2008.017 · Cited by 16

Treating brain diseases using systemic parenterally-administered protein therapeutics: Dysfunction of the brain barriers and potential strategies

Zaghmi, A., Drouin‐Ouellet, J., Brambilla, D., & Gauthier, M. A. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120461 · Cited by 17

Drug delivery to the brain using colloidal carriers

Chang, J., Jallouli, Y., Barras, A., Dupont, N., & Betbeder, D. (2009) · Progress in brain research · doi:10.1016/s0079-6123(08)80001-5 · Cited by 15

Recent Advances in Nanodrug Delivery Systems Production, Efficacy, Safety, and Toxicity

Lopalco, A., Iacobazzi, R. M., Lopedota, A., & Denora, N. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-4003-6_15 · Cited by 16

Drug transport to brain with targeted nanoparticles

Olivier, J. (2005) · Neurotherapeutics · doi:10.1007/bf03206647 · Cited by 15

Nanoparticles of alkylglyceryl dextran and poly(ethyl cyanoacrylate) for applications in drug delivery: Preparation and characterization

Ibegbu, M. D., Boussahel, A., Cragg, S. M., Tsibouklis, J., & Barbu, E. (2016) · International Journal of Polymeric Materials · doi:10.1080/00914037.2016.1201827 · Cited by 13

Vectorization of Harungana madagascariensis Lam. ex Poir. (Hypericaceae) ethanolic leaf extract by using PLG‐nanoparticles: antibacterial activity assessment

Moulari, B., Lboutounne, H., Pellequer, Y., Guillaume, Y. C., Millet, J., & Pirot, F. (2005) · Drug Development Research · doi:10.1002/ddr.20004 · Cited by 13

Exploring the Potential of Nasal Drug Delivery for Brain Targeted Therapy: A Detailed Analysis

Ghosh, M., Roy, D., Thakur, S., & Singh, A. (2024) · Biopharmaceutics & Drug Disposition · doi:10.1002/bdd.2400 · Cited by 14

Surface modified Polymeric Nanoparticles for Brain Targeted drug Delivery

Lahkar, S., & Das, M. K. (2013) · Current Trends in Biotechnology and Pharmacy · Cited by 12

How Nanoparticle Physicochemical Parameters Affect Drug Delivery to Cells in the Retina via Systemic Interactions

You, Q., Sokolov, M., Grigartzik, L., Hintz, W., Wachem, B. G. M. V., Henrich‐Noack, P., & Sabel, B. A. (2019) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.9b01046 · Cited by 12

Poly(Alkyl Cyanoacrylate) Nanoparticles for Delivery of Anti-Cancer Drugs

Murthy, R. S. R., & Reddy, L. H. (2006) · CRC Press eBooks · doi:10.1201/9781420006636-15 · Cited by 12

Introduction to Active, Smart, and Intelligent Nanomaterials for Biomedical Application

Ahlawat, J., & Narayan, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817830-0.00001-1 · Cited by 11

Multifunctional Polymeric Nanosystems for Tumor-Targeted Delivery

Magadala, P., van Vlerken, L. E., Shahiwala, A., & Amiji, M. M. (2008) · Fundamental biomedical technologies · doi:10.1007/978-0-387-76554-9_2 · Cited by 11

Poly(Alkyl Cyanoacrylate) Nanoparticles for Delivery of Anti-Cancer Drugs

Murthy, R. S. R., & Reddy, L. H. (2006) · CRC Press eBooks · doi:10.1201/9781420006636.ch15 · Cited by 10

Schleuservermittelter Transport von Wirkstoffen ins Gehirn

Malakoutikhah, M., Teixidò, M., & Giralt, E. (2011) · Angewandte Chemie · doi:10.1002/ange.201006565 · Cited by 9

Does Pharmacodynamics of Drugs Change After Presenting them as Nanoparticles Like their Pharmacokinetics?

Jafari, R. M., Ala, M., Goodarzi, N., & Dehpour, A. R. (2020) · Current Drug Targets · doi:10.2174/1389450121666200128113547 · Cited by 9

RNAi-Based Approaches to Control Mycotoxin Producers: Challenges and Perspectives

Stakheev, A. A., Taliansky, M. E., Kalinina, N. O., & Завриев, С. К. (2024) · Journal of Fungi · doi:10.3390/jof10100682 · Cited by 8

Patents on Brain Permeable Nanoparticles

Gulati, M., Chopra, D., Singh, S. K., Saluja, V., Pathak, P., & Bansal, P. (2014) · Recent Patents on CNS Drug Discovery · doi:10.2174/1574889808666131128105141 · Cited by 7

Biodegradable Polymeric Nanoparticles for Brain-Targeted Drug Delivery

Kempe, K., & Nicolazzo, J. A. (2020) · Neuromethods · doi:10.1007/978-1-0716-0838-8_1 · Cited by 8

Clinical Toxicity of Nanomedicines

Ahamad, N., Bhardwaj, P., Bhatia, E., & Banerjee, R. (2020) · Springer eBooks · doi:10.1007/978-981-15-6255-6_20 · Cited by 8

RNAi biopesticides for precision control of invasive pests and pathogens in 3D forests: Quantum leap towards eco-friendly alternatives

Sarkar, S., Mogilicherla, K., Chakraborty, A., He, P., Smagghe, G. J., & Roy, A. (2025) · Environmental Technology & Innovation · doi:10.1016/j.eti.2025.104404 · Cited by 7

Adverse Effects of Non-Metallic Nanoparticles in the Central Nervous System

Sikorska, K., Sawicki, K., Czajka, M., Kapka‐Skrzypczak, L., Kruszewski, M. K., & Brzóska, K. (2023) · Materials · doi:10.3390/ma16237264 · Cited by 7

Investigating Interactions Between Nanoparticles and Cells: Internalization and Intracellular Trafficking

Hillaireau, H. (2016) · Springer eBooks · doi:10.1007/978-3-319-41421-8_10 · Cited by 9

Cell and organ drug targeting

Ghosh, D., Upmanyu, N., Shukla, T., & Shrivastava, T. P. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816505-8.00015-1 · Cited by 7

A Drug Delivery to Improve Prognosis of Traumatic Brain Injury Mice Through Mouse‐Derived Nerve Growth Factor Coated by a Nanoparticle

Zhao, R., Dong, S., Wu, D., Tian, Y., Yuan, J., Mi, L., Wu, C., Tong, S., & Jiang, R. (2025) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70603 · Cited by 4

The Application of Polybutyl Cyanoacrylate (PBCA) Nanoparticles in Delivering Cancer Drugs

Salehi, V., Izadkhah, M., Salehi, H., Pour, N. S., & Ghanbarikondori, P. (2024) · Asian Pacific Journal of Cancer Biology · doi:10.31557/apjcb.2024.9.2.209-218 · Cited by 4

Poly(Butyl Cyanoacrylate) Nanoparticles Deliver β-Nerve Growth Factor to the Brain After Traumatic Brain Injury

Lin, Y. (2024) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-031-49744-5_6 · Cited by 4

Polymers for Peptide/Protein Drug Delivery

Chevalier, M. T., González, J. S., & Álvarez, V. A. (2015) · Wiley eBooks · doi:10.1002/9781119041375.ch14 · Cited by 4

Formulation of therapeutic synthetic polymers for drug and gene delivery ▾

Pardridge, W. M. (2002) · Drug Discovery Today · doi:10.1016/s1359-6446(02)02505-9 · Cited by 4

From Polymer Chemistry and Physicochemistry to Nanoparticulate Drug Carrier Design and Applications

Vauthier, C., Fattal, E., & Labarre, D. (2003) · doi:10.1201/9780203913338-26 · Cited by 4

A Brief Review on Nanomedicine and the Therapeutic Applications of Gold Nanoparticles

Kamel, B., El-Nabtity, S., AbdelHafeez, M., Mehanna, E. T., & Abo–Elmatty, D. M. (2022) · Records of Pharmaceutical and Biomedical Sciences/Records of Pharmaceutical & Biomedical Sciences · doi:10.21608/rpbs.2022.164899.1175 · Cited by 3

Nanomedicine in Brain Tumors

(2013) · CRC Press eBooks · doi:10.1201/b15403-17 · Cited by 3

Brain Delivery by Nanoparticles

Gelperina, S. E. (2006) · Drugs and the pharmaceutical sciences · doi:10.1201/9780849374555.ch10 · Cited by 3

Nanoparticles for the Treatment of A lzheimer's Disease: Theoretical Rationale, Present Status and Future Perspectives

Liu, G., Men, P., Perry, G. L., & Smith, M. A. (2003) · Wiley eBooks · doi:10.1002/9783527610419.ntls0122 · Cited by 3

Supramolecularassemblies for the active drug targeting to the brain

Béduneau, A., Pellequer, Y., & Lamprecht, A. (2009) · Journal of Drug Delivery Science and Technology · doi:10.1016/s1773-2247(09)50030-5 · Cited by 2

DRUG INDUCED ENDOTHELIAL DYSFUNCTION: FUNCTIONAL ROLE OF OXIDATIVE STRESS

Ajithkumar, S. G. N., Ramachandran, S., & Kartha, C. S. (2011) · Cited by 2

Nanoparticulate Systems for Central Nervous System Drug Delivery

Olivier, J., & de Oliveira, M. P. (2007) · Drugs and the pharmaceutical sciences · doi:10.1201/9781420008449.ch17 · Cited by 2

Nanopolymers and Nanoconjugates for Central Nervous System Diagnostics and Therapies

Suffredini, G., & Lucien Levy, C. (2013) · CRC Press eBooks · doi:10.1201/b15274-4 · Cited by 2

Nanoparticle: Significance as Smart Material in Therapeutic Strategies in Drug Delivery in Biological Systems

Dhungel, K., & Narayan, J. (2019) · Springer eBooks · doi:10.1007/978-981-13-7142-4_16 · Cited by 4

Nanocarriers for Overcoming Multidrug Resistance in Cancers

Banerjee, R. (2006) · Nanomedicine · doi:10.2217/17435889.1.4.481 · Cited by 2

Brain Delivery by Nanoparticles

Gelperina, S. E. (2006) · doi:10.1201/9780849374555-12 · Cited by 2

From Polymer Chemistry and Physicochemistry to Nanoparticulate Drug Carrier Design and Applications

Fattal, E., Labarre, D., & Vauthier, C. (2003) · CRC Press eBooks · doi:10.1201/9780203913338.ch26 · Cited by 2

Targeting Drugs into the Central Nervous System

Prókai, L. (2002) · Springer eBooks · doi:10.1007/978-1-4757-4627-3_19 · Cited by 2

Nanobiotechnology: A new generation of biomedicine - Innovative nanotechnology in key areas of biomedical engineering and cancer therapy

Tosi, G., Ruozi, B., Badiali, L., Bondioli, L., Belletti, D., Forni, F., & Vandelli, M. A. (2012) · IRIS UNIMORE (University of Modena and Reggio Emilia) · doi:10.4032/9789814267359 · Cited by 1

Nanopreparations for Central Nervous System Diseases

Xu, L., & Yang, H. (2014) · Frontiers in nanobiomedical research · doi:10.1142/9789814520652_0023 · Cited by 1

A Review on Poly-Lactic-Co-Glycolic Acid as a Unique Carrier for Controlled and Targeted Delivery Drugs

Prakash Raj, K., Kathiresan, K., & Pandian, P. L. (2021) · Journal of Evolution of Medical and Dental Sciences · doi:10.14260/jemds/2021/416 · Cited by 1

Modification of Nano-sized Materials for Drug Delivery

Xu, T., Nichols, H. L., Zhang, N., & Wen, X. (2009) · Springer eBooks · doi:10.1007/978-3-540-49661-8_15 · Cited by 1

Multifunctional Polymeric Enveloped Nanocarriers: Targeting Extracellular and Intracellular Barriers

Kiani, M. H., Yasinzai, M., & Shahnaz, G. (2018) · InTech eBooks · doi:10.5772/intechopen.74624 · Cited by 1

Nano-engineering Nanoparticles for Clinical Use in the Central Nervous System: Clinically Applicable Nanoparticles and Their Potential Uses in the Diagnosis and Treatment of CNS Aliments

Chen, S., Auriat, A. M., Koudrina, A., DeRosa, M. C., Cao, X., & Tsai, E. C. (2019) · Springer eBooks · doi:10.1007/978-3-030-31261-9_7 · Cited by 1

Polymer Nanoparticles and Their Cellular Interactions

Mailänder, V., & Landfester, K. (2011) · Nanotechnologies for the Life Sciences · doi:10.1002/9783527610419.ntls0255 · Cited by 1

Mechanistic Profiling of Novel Wafer Technology Developed for Rate-Modulated Oramucosal Drug Delivery

Patel, R. (2006) · University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg) · Cited by 1

Immunociblage du cerveau par des nanocapsules lipidiques

Béduneau, A. (2007) · OpenGrey (Institut de l'Information Scientifique et Technique) · Cited by 1

Formulation of novel polymer coated iron oxide nanoparticles

Abushrida, A. (2012) · Nottingham ePrints (University of Nottingham)

Atteindre les neurones

Betdeder, P. D., Cecchelli, R., Dehouck, M., & Fénart, L. (2000) · Biofutur · doi:10.1016/s0294-3506(00)88182-x

Umwelt- und Gesundheitsrisiken nanotechnologischer Applikationen

Peter, P. (2005) · Repository for Publications and Research Data (ETH Zurich) · doi:10.3929/ethz-a-005044667

Research Article A relevant in vitro rat model for the evaluation of blood-brain barrier translocation of nanoparticles

García-García, E., Andrieux, K., Desmaële, D., Nicolas, V., Georgin, D., & Couvreur, P. (2005)

Direct Evidence That Polysorbate-80-Coated Poly(Butylcyanoacrylate) Nanoparticles Deliver Drugs to the CNS via Specific Mechanisms Requiring Prior Binding of Drug to the Nanoparticles

Kreuter, J., Ramge, P., Petrov, V. E., Hamm, S., Gelperina, S. E., Engelhardt, B., Alyautdin, R. N., von Briesen, H., & Begley, D. J. (2003) · Pharmaceutical Research · doi:10.1023/a:1022604120952 · Cited by 469

Analgesic activity of the hexapeptide dalargin adsorbed on the surface of polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles

Alyautdin, R. N., Gothier, D., Петров, Kharkevich, D. A., & Kreuter, J. (1995) · European Journal of Pharmaceutics and Biopharmaceutics · Cited by 148

[Transport of the hexapeptide dalargin across the hemato-encephalic barrier into the brain using polymer nanoparticles].

Аляутдин, Р. Н., Petrov, V. E., Aa, I., Kreuter, J., & Kharkevich, D. A. (1996) · PubMed · Cited by 9

Double-Coated Poly (Butylcynanoacrylate) Nanoparticulate Delivery Systems for Brain Targeting of Dalargin Via Oral Administration

Das, D., & Lin, S. (2005) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.20357 · Cited by 117

Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections

Schröder, U., & Sabel, B. A. (1996) · Brain Research · doi:10.1016/0006-8993(95)01375-x · Cited by 141