The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease
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Citations
Cites
Dauer, W., & Przedborski, S. (2003) · Neuron · doi:10.1016/s0896-6273(03)00568-3 · Cited by 5,469
Self-citationJavitch, J. A., D'Amato, R. J., Strittmatter, S. M., & Snyder, S. H. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.7.2173 · Cited by 1,263
Nicklas, W. J., Vyas, I., & Heikkila, R. E. (1985) · Life Sciences · doi:10.1016/0024-3205(85)90146-8 · Cited by 1,262
Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
Chiba, K., Trevor, A., & Castagnoli, N. (1984) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(84)91293-2 · Cited by 1,097
Heikkila, R. E., Manzino, L., Cabbat, F. S., & Duvoisin, R. C. (1984) · Nature · doi:10.1038/311467a0 · Cited by 1,010
Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism
Markey, S. P., Johannessen, J. N., Chiueh, C. C., Burns, R. S., & Herkenham, M. A. (1984) · Nature · doi:10.1038/311464a0 · Cited by 786
Jackson-Lewis, V., Jakowec, M., Burke, R. E., & Przedborski, S. (1995) · Neurodegeneration · doi:10.1016/1055-8330(95)90015-2 · Cited by 609
Self-citationD-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
Tieu, K., Perier, C., Caspersen, C., Teismann, P., Wu, D.-C., Yan, S.-D., Naini, A., Vila, M., Jackson-Lewis, V., Ramasamy, R., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200318797 · Cited by 497
Self-citationRamsay, R. R., & Singer, T. P. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57434-8 · Cited by 412
Vila, M., Jackson-Lewis, V., Vukosavic, S., Djaldetti, R., Liberatore, G., Offen, D., Korsmeyer, S. J., & Przedborski, S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051633998 · Cited by 372
Self-citation
Cited by
Mitochondrial membrane permeabilization in cell death
Kroemer, G., Galluzzi, L., & Brenner, C. (2007) · Physiological Reviews · doi:10.1152/physrev.00013.2006 · Cited by 3,598
St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J. M., Rhee, J., Jäger, S., Handschin, C., Zheng, K., Lin, J., Yang, W., et al. (2006) · Cell · doi:10.1016/j.cell.2006.09.024 · Cited by 2,233
Microglial Activation and Chronic Neurodegeneration
Lull, M. E., & Block, M. L. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.05.014 · Cited by 1,047
“For example, to damage DA neurons, MPTP is metabolized to 1-methyl-4-phenylpyridinium (MPP ), which is then selectively taken up by the dopamine transporter, resulting in inhibition of the mitochondrial electron transport chain complex I.(160) In addition to this mechanism of direct neurotoxicity, MPTP-induced neuroto…”
BackgroundToxin-induced models of Parkinson’s disease
Bové, J., Prou, D., Perier, C., & Przedborski, S. (2005) · NeuroRX · doi:10.1602/neurorx.2.3.484 · Cited by 739
Self-citationAshrafi, G., Schlehe, J. S., LaVoie, M. J., & Schwarz, T. L. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201401070 · Cited by 502
“…et al., 2006; Navarro et al., 2009) and PDlike symptoms caused by mitochondrial drugs, such as Rotenone and MPTP (1methyl4phenyl1,2,3,6tetrahydro pyridine; Betarbet et al., 2000; Przedborski et al., 2004), were the first lines of evidence linking mitochondrial dysfunction to the pathology of PD.”
Background
Metadata
- Authors
- Przedborski, S., Tieu, K., Perier, C., & Vila, M.
- Venue
- Journal of Bioenergetics and Biomembranes
- Published
- 2004-08
- Volume
- 36
- Issue
- 4
- Pages
- 375-379
- ISSN
- 0145-479X (ISSN-L)
- 1573-6881
- OpenAlex
- W2054415450
- Cited by
- 287
- References
- 43
- FWCI
- 8.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease. https://app.cochat.ai/papers/10.1023/b:jobb.0000041771.66775.d5
- The paper
- Przedborski, S., Tieu, K., Perier, C., & Vila, M. (2004). MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease. Journal of Bioenergetics and Biomembranes. https://doi.org/10.1023/b%3Ajobb.0000041771.66775.d5
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
